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T12912Sigma-1 receptor antagonist 3
Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)
价 格:¥电议型 号:T12912产 地:中国大陆
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T12911Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
价 格:¥电议型 号:T12911产 地:中国大陆
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T12910Sigma-1 receptor antagonist 1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies.
价 格:¥电议型 号:T12910产 地:中国大陆
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T12910Sigma-1 receptor antagonist 1Sigma-1 receptor antagonist 1
Sigma-1 receptor antagonist 1 is a potent and selective antagonist of sigma-1 receptor (σ1R) with Ki of 1.06 nM, has antineuropathic pain activity.
价 格:¥电议型 号:T12910产 地:美洲
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T12911Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
价 格:¥电议型 号:T12911产 地:美洲
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T12912Sigma-1 receptor antagonist 3Sigma-1 receptor antagonist 3
Sigma-1 receptor antagonist 3 is a potent and selective antagonist of Sigma-1 (σ1) receptor(Ki : 1.14 nM), has the potential for the neuropathic pain.
价 格:¥电议型 号:T12912产 地:美洲
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T78734Sigma-1 receptor antagonist 5;化合物 Sigma-1 receptor antagonist 5Sigma-1 receptor antagonist 5
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors (Ki=4.5 nM (σ1R), 10 nM (σ2R)) and the histamine H3 receptor (hH3R, Ki=7.7 nM, IC50=215 nM). It effectively attenuates Capsaicin-induced nociception and demonstrates significant antinociceptive effects in both nociceptive and neuropathic pain models [1].
价 格:¥电议型 号:T78734产 地:中国大陆
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T74813Sigma-1 receptor antagonist 4;化合物 Sigma-1 receptor antagonist 4Sigma-1 receptor antagonist 4
Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine´s analgesic effects and reverses morphine-induced analgesic tolerance, potentially preventing morphine tolerance [1].
价 格:¥电议型 号:T74813产 地:中国大陆
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T12912Sigma-1 receptor antagonist 3;化合物Sigma-1 receptor antagonist 3Sigma-1 receptor antagonist 3
Sigma-1 receptor antagonist 3 is a more potent and selective antagonist of Sigma-1 (σ1) receptor (Ki = 1.14 nM) than σ2 receptor(Ki = 1239 nM). Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG, IC50 = 1.54 μM)
价 格:¥电议型 号:T12912产 地:中国大陆
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T12911Sigma-1 receptor antagonist 2;化合物Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
价 格:¥电议型 号:T12911产 地:中国大陆
-
T12910Sigma-1 receptor antagonist 1;化合物Sigma-1 receptor antagonist 1Sigma-1 receptor antagonist 1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies.
价 格:¥电议型 号:T12910产 地:中国大陆