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T9543Syk Inhibitor II hydrochlorideSyk Inhibitor II hydrochloride
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of these factors are detectable in the serum of Fc gamma receptor IIb-deficient (FcgRIIb-/-) mice with sepsis. Syk inhibition downregulated several inflammatory pathways in FcgRIIb-/- macrophages activated with BG + LPS suggesting the potential anti-inflammatory impact of Syk inhib
价 格：￥电议型 号：T9543产 地：中国大陆
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T6776BAY 61-3606 dihydrochlorideBAY 613606 dihydrochloride,Spleen tyrosine kinase,inhibit,Syk,Inhibitor,A
BAY-61-3606 is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).
价 格：￥电议型 号：T6776产 地：中国大陆
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T4391Syk Inhibitor II (hydrochloride)
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibit
价 格：￥电议型 号：T4391产 地：中国大陆
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T4348Syk Inhibitor II
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
价 格：￥电议型 号：T4348产 地：中国大陆
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T4263BAY 61-36062-[[7-(3,4-二甲氧基苯基)咪唑并[1,2-C]嘧啶-5-基]氨基]-3-吡啶甲酰胺；Syk inhibitor IV
BAY 61-3606 is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.
价 格：￥电议型 号：T4263产 地：中国大陆
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T79443Syk-IN-8；化合物 Syk-IN-8Syk-IN-8
Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells. It specifically inhibits PLCγ2 phosphorylation and is applicable for blood cancer research [1].
价 格：￥电议型 号：T79443产 地：中国大陆
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T78943Syk-IN-7；化合物 Syk-IN-7Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].
价 格：￥电议型 号：T78943产 地：中国大陆
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T76083Syk Kinase Peptide Substrate, Biotin labeled；化合物 Syk Kinase Peptide Substrate, Biotin labeledSyk Kin
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.
价 格：￥电议型 号：T76083产 地：中国大陆
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T70931SYK-IN-II；化合物 SYK-IN-IISYK-IN-II
SYK-IN-II is an inhibitor of the spleen tyrosine kinase (STK).
价 格：￥电议型 号：T70931产 地：中国大陆
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T70930GSK SYK inhibitor；化合物 GSK SYK inhibitorGSK SYK inhibitor
The immunoregulator spleen tyrosine kinase (SYK) is upregulated in cutaneous lupus erythematosus (CLE). This double-blind, multicentre, Phase Ib study evaluated the safety, tolerability, pharmacokinetics, pharmacodynamics and clinical efficacy of the selective SYK inhibitor GSK2646264 in active CLE lesions
价 格：￥电议型 号：T70930产 地：中国大陆
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T63086SYK/JAK-IN-1；化合物 SYK/JAK-IN-1SYK/JAK-IN-1
SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.
价 格：￥电议型 号：T63086产 地：中国大陆
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T62691Syk Inhibitor II dihydrochloride dihydrate；化合物 Syk Inhibitor II dihydrochloride dihydrateSyk Inhibit
Syk Inhibitor II dihydrochloride dihydrate is a highly selective, potent, ATP-competitive Syk inhibitor (IC50: 41 nM). Syk Inhibitor II dihydrochloride dihydrate exhibits anti-allergic effects.
价 格：￥电议型 号：T62691产 地：中国大陆
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T4391Syk Inhibitor II dihydrochloride；化合物Syk Inhibitor II (hydrochloride)Syk Inhibitor II (hydrochloride)
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that, upon phosphorylation, binds to immunoreceptor tyrosine-based activation motifs of FcRγ chains and mediates downstream signaling related to platelet function and inflammation. Syk inhibitor II is a cell-permeable, pyrimidine-carboxamide compound that selectively and reversibly blocks Syk (IC50 = 41 nM) in an ATP-competitive manner. It is much less potent against PKCε, PKCβII, ZAP-70, Btk, and Itk (IC50s = 5.1, 11, 11.2, 15.5, an
价 格：￥电议型 号：T4391产 地：中国大陆
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T4348Syk Inhibitor II；化合物Syk Inhibitor IISyk Inhibitor II
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
价 格：￥电议型 号：T4348产 地：中国大陆
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T4263BAY 61-3606；化合物BAY 61-3606Syk inhibitor IV；2-[[7-(3,4-二甲氧基苯基)咪唑并[1,2-C]嘧啶-5-基]氨基]-3-吡啶甲酰胺|||Syk inhi
BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src.
价 格：￥电议型 号：T4263产 地：中国大陆
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T40976Syk Kinase Peptide Substrate；Syk Kinase Peptide SubstrateSyk Kinase Peptide Substrate
Syk Kinase Peptide Substrate is a Syk kinase peptide substrate.
价 格：￥电议型 号：T40976产 地：中国大陆
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T37077Syk-IN-4；Syk-IN-4Syk-IN-4
Syk-IN-4 is a potent, selective, and orally bioavailable inhibitor of SYK, demonstrating an IC50 of 0.31 nM. It targets SYK, which has been identified as a potential therapeutic target for autoimmunity and hematological cancers[1].
价 格：￥电议型 号：T37077产 地：中国大陆
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T28281OXSI-2；化合物OXSI-2OXSI 2|||Syk Inhibitor；OXSI 2|||Syk Inhibitor
OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated events in platelets.
价 格：￥电议型 号：T28281产 地：中国大陆
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T24843Syk-IN-1化合物 T24843SykIN11|||Syk-IN-11|||Syk IN 11|||Syk inhibitor-11|||Syk inhibitor 11|||Syk-inhibi
Syk-IN-11 is a selective Syk inhibitor.
价 格：￥电议型 号：T24843产 地：中国大陆
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T13045Syk-IN-3；Syk 抑制剂 3Syk-IN-3
Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.
价 格：￥电议型 号：T13045产 地：中国大陆
