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T11402GKI-1GKI1,GKI 1
GKI-1 is a Greatwall (GWL) kinase inhibitor with IC 50 s of 4.9 and 2.5 μM against hGWL FL and hGWL-KinDom, respectively. Greatwall (GWL) has been proposed as a novel cancer therapy target. GKI-1 robustly inhibits ROCK1 with an IC 50 of 11 μM, but only weakly affected PKA [1].
价 格:¥电议型 号:T11402产 地:中国大陆
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T11402LGKI-1 HCl;GKI-1盐酸盐GKI-1 HCl( 2444764-03-6 Free base);GKI-1 HCl( 2444764-03-6 Free base)
GKI-1 HCl is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL and hGWL-KinDom.The inhibitory effect of GKI-1 HCl on ROCK1 is more significant.
价 格:¥电议型 号:T11402L产 地:中国大陆
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T11402GKI-1;化合物GKI-1GKI-1
GKI-1 is a Greatwall (GWL) kinase inhibitor that inhibits hGWLFL with an IC50 of 4.9. GKI-1 also inhibited hGWL-KinDom, and its IC50 was 2.5 ?M. The inhibitory effect of GKI-1 on ROCK1 was better than that of hGWLFL and hGWL-KinDom, and its IC50 was 11 ?M, which only weakly inhibited PKA.
价 格:¥电议型 号:T11402产 地:中国大陆