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T1402120-HETE20-HETE,20-hydroxy Arachidonic Acid,
20-HETE (20-hydroxy Arachidonic Acid) is a CYP450 metabolite and a potent vasoconstrictor and it is an endogenous inhibitor of the large-conductance Ca2+-activated K+ channel in renal arterioles. 20-HETE increases NADPH oxidase, ROS, and NF-κB activity, a
价 格:¥电议型 号:T14021产 地:美洲
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T1402120-HETE;化合物 T1402120-hydroxy Arachidonic Acid;20-hydroxy Arachidonic Acid
20-HETE (20-hydroxy Arachidonic Acid) is a CYP450 metabolite and a potent vasoconstrictor and it is an endogenous inhibitor of the large-conductance Ca2+-activated K+ channel in renal arterioles. 20-HETE increases NADPH oxidase, ROS, and NF-κB activity, and it also inhibits endothelial NO synthase and inhibits apoptosis of pulmonary artery smooth muscle cells[1][2]. 20-HETE constricts smooth muscles, stimulates smooth muscle proliferation and migration.
价 格:¥电议型 号:T14021产 地:中国大陆