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T26963CBR-2092;化合物 T26963TNP2092|||CBR2092|||TNP-2092|||TNP 2092;TNP2092|||CBR2092|||TNP-2092|||TNP 2092
CBR-2092 is a DNA-directed RNA polymerase and DNA topoisomerase inhibitor. CBR-2092 exhibited rifampin-like potency as an inhibitor of RNA polymerase, was an equipotent (balanced) inhibitor of DNA gyrase and DNA topoisomerase IV, and retained activity against a prevalent quinolone-resistant variant. Studies of mutant strains that exhibited reduced susceptibility to CBR-2092 further substantiated RNA polymerase as the primary cellular target of CBR-2092, with DNA gyrase and DNA topoisomerase IV b
价 格:¥电议型 号:T26963产 地:中国大陆