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T77579JC2-11；化合物JC2-11JC2-11
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate
价 格：￥电议型 号：T77579产 地：中国大陆
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T77578CHBO4；化合物CHBO4CHBO4
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and the Ki value was 0.010 ± 0.005 μM.CHBO4 reduces cellular damage by scavenging intracellular reactive oxygen species (ROS), and can be used to study Parkinson´s disease (PD).
价 格：￥电议型 号：T77578产 地：中国大陆
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T77577SLU-PP-332；化合物SLU-PP-332SLU-PP-332
SLU-PP-332 is a pan-estrogen receptor-related receptor (ERR) agonist with high affinity for ERRα, ERRβ, and ERRγ with EC50 values of 98, 230, and 430 nM, respectively.SLUPP-332 enhances mitochondrial function and cellular respiration, increases type IIa oxidized skeletal muscle fibers, and enhances exercise tolerance in skeletal muscle cell lines. SLU-PP-332 has the potential to be used in the study of metabolic diseases and improvement of muscle function, and may be used to ameliorate metabolic
价 格：￥电议型 号：T77577产 地：中国大陆
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T7757617β-HSD10-IN-1；17β-HSD10抑制剂117β-HSD10-IN-1
17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of Alzheimer´s disease.
价 格：￥电议型 号：T77576产 地：中国大陆
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T77575P-gb-IN-1；P-gb抑制剂1P-gb-IN-1
P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow. P-gb-IN-1 has been shown to inhibit P-gp by hydrogen bonding with residues Asn 721 and Met 986. P-gb-IN-1 showed low toxicity in MCF-7/ADR cells.
价 格：￥电议型 号：T77575产 地：中国大陆
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T77574ROS inducer 1；ROS诱导剂1ROS inducer 1
ROS inducer 1 is a small molecule compound with bactericidal activity that inhibits the production of ROS in Xanthomonas axonopodis pv. citri (Xac), Xanthomonas oryzae pv. oryzae (Xoo) and Pseudomonas syringae pv. actinidiae (Psa). ROS inducer 1 induces ROS production in Xanthomonas cells and can be used to study bacterial infections in crops.
价 格：￥电议型 号：T77574产 地：中国大陆
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T77571Bcl-B inhibitor 1；Bcl-B 抑制剂1Bcl-B inhibitor 1
Bcl-B inhibitor 1 is a Bcl-B inhibitor with antitumor activity that binds to and inactivates pro-apoptotic proteins in the BH3 structural domain.
价 格：￥电议型 号：T77571产 地：中国大陆
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T77570AP-C2；化合物AP-C2AP-C2
AP-C2 is a potent small molecule guanosine 3´,5´-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII.
价 格：￥电议型 号：T77570产 地：中国大陆
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T7757Cereblon Ligand -Linker Conjugates 2 TFA化合物 T7757Cereblon Ligand -Linker Conjugates 2 TFA|||Cereblon
Cereblon Ligand -Linker Conjugates 2 TFA is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
价 格：￥电议型 号：T7757产 地：中国大陆
