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T79151TLR8 agonist 6;化合物 TLR8 agonist 6TLR8 agonist 6
Compound A, a potent TLR8 agonist, exhibits an EC50 of 0.052 ?M and promotes the production of IL-12p40 in human PBMCs with an EC50 of 0.031 ?M. This compound is applicable for research in virus resistance, infection resistance, autoimmunity, and tumor studies [1].
价 格:¥电议型 号:T79151产 地:中国大陆
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T7347CU-CPT-8m;化合物CU-CPT-8mTLR8-specific antagonist;TLR8-specific antagonist
CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)
价 格:¥电议型 号:T7347产 地:中国大陆
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T7302CU-CPT9b;化合物CU-CPT9bCU-CPT-9b|||TLR8-specific antagonist 1;CU-CPT-9b|||TLR8-specific antagonist 1
CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits activation of NF- B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
价 格:¥电议型 号:T7302产 地:中国大陆
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T72830TLR8 agonist 5;化合物 TLR8 agonist 5TLR8 agonist 5
TLR8 Agonist 5, exhibiting potent efficacy as a TLR8 agonist, demonstrates an EC50 of 20 nM in HEK-Blue hTLR8, effectively activating the immune response.
价 格:¥电议型 号:T72830产 地:中国大陆
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T63848TLR8 agonist 4;化合物 TLR8 agonist 4TLR8 agonist 4
TLR8 agonist 4 was effective in inhibiting both wild-type and drug-resistant (lamivudine and entecavir) HBV strains with their IC50 values of 0.15 and 0.10 μM, respectively.
价 格:¥电议型 号:T63848产 地:中国大陆
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T40040TLR8 agonist 2 hydrochloride;TLR8 agonist 2 hydrochlorideTLR8 agonist 2 hydrochloride
TLR8 agonist 2 hydrochloride is a highly potent and selective agonist for human TLR8, exhibiting an EC50 of 3 nM. However, its activity towards human TLR7 is considerably weaker, with an EC50 of 33.33 μM.
价 格:¥电议型 号:T40040产 地:中国大陆
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T40039TLR8 agonist 2TLR8 agonist 2TLR8 agonist 2
TLR8 agonist 2 is a highly effective and specific compound that activates TLR8, possessing an EC 50 of 3 nM in human TLR8. Notably, TLR8 agonist 2 demonstrates lower activity towards human TLR7, with an EC 50 of 33.33 μM.
价 格:¥电议型 号:T40039产 地:中国大陆