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T2627Nolatrexed dihydrochlorideNolatrexed dihydrochloride,Thymitaq,AG 337
Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymid
价 格：￥电议型 号：T2627产 地：美洲
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T2627Nolatrexed dihydrochloride；盐酸诺拉曲塞Thymitaq|||AG 337；盐酸诺拉曲塞|||Thymitaq|||AG 337
Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
价 格：￥电议型 号：T2627产 地：中国大陆
