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产品数:86101
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T6683STF-62247renal,STF-62247,VHL,carcinoma,inhibit,cytotoxic,cell,RCC,Inhibitor,STF62247,intracytoplasmi
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
价 格:¥电议型 号:T6683产 地:中国大陆
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T8320J14cancer,inhibit,damage,Sulfiredoxin,J14,cytotoxicity,Reactive Oxygen Species,J 14,death,adenocarci
J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death
价 格:¥电议型 号:T8320产 地:中国大陆
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T9050AG-270inhibit,Inhibitor,cancer,Low,solid,AG-270,SAM,pancreatic,lymphoma,tumor,AG 270,toxicity,AG270
AG-270 is an allosteric and orally active inhibitor of MAT2A.
价 格:¥电议型 号:T9050产 地:中国大陆
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T9014SKI-178resistant,SphK,cytotoxic,myeloid,Inhibitor,Apoptosis,leukemia,multi-drug,inhibit,SKI-178,canc
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.
价 格:¥电议型 号:T9014产 地:中国大陆
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T8849PF-9601Nexcitotoxicity,neurodegenerative diseases,MAO,PF9601N,Monoamine Oxidase,MAO-B inhibitor,neur
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
价 格:¥电议型 号:T8849产 地:中国大陆
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T7846Aegelineαsyn,Aegeline,yeast,Inhibitor,protein,Sec22p,inhibit,toxicity,Fungal,SNARE
Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.
价 格:¥电议型 号:T7846产 地:中国大陆
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T6566Levobupivacaine hydrochlorideCNS toxicity,gastric cancer,Na channels,Erastin,Inhibitor,analgesic,ana
Levobupivacaine HCl is a reversible neuronal sodium channel inhibitor, which is the pure S(-)-enantiomer of bupivacaine. It was utilized as a long-acting local anesthetic.
价 格:¥电议型 号:T6566产 地:中国大陆
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T8233BRD3308β-cells,glucolipotoxicity,inflammatory,BRD-3308,Human immunodeficiency virus,BRD3308,Histone
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
价 格:¥电议型 号:T8233产 地:中国大陆
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T41277PACMA 31bond,tumor,ovarian,athymic,PACMA31,inhibit,toxicity,colony,PACMA-31,mice,PACMA 31,oral,Inhib
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.
价 格:¥电议型 号:T41277产 地:中国大陆
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T6953Prilocainelocal,anaesthetize,inhibit,Inhibitor,Sodium potassium pump,Na(+),K(+),neurotoxic,Na+/K+ AT
Prilocaine is a local anesthetic of the amino amide type, which acts on the sodium channel on the neuronal membrane and limits the spread of seizures.
价 格:¥电议型 号:T6953产 地:中国大陆
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T8822JNJ-5207852 dihydrochlorideInhibitor,toxicity,JNJ5207852,inhibit,low,JNJ 5207852,sleep,REM,JNJ-52078
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor.
价 格:¥电议型 号:T8822产 地:中国大陆
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TN1739Homodihydrocapsaicin Iphytotoxic,Capsicum annuum,Capsaicinoid,Homodihydrocapsaicin I,Inhibitor,inhib
Homodihydrocapsaicin I is a natural product from Capsicum annuum L.
价 格:¥电议型 号:TN1739产 地:中国大陆
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T8235L-732138cytotoxicity,vagally-induced,NK receptor,Neurokinin Receptor,Inhibitor,ntravenously,lipopoly
L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)
价 格:¥电议型 号:T8235产 地:中国大陆
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TN7043Neolancerincytotoxic,natural,Inhibitor,product,Neolancerin,inhibit
Neolancerin is a natural product isolated from adventitious roots of St. John’s wort (Hypericum perforatum L.).
价 格:¥电议型 号:TN7043产 地:中国大陆
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T6456CRT0044876non-toxic,DNA,Inhibitor,base,exonuclease,inhibit,CRT0044876,endonuclease,DNA/RNA Synthesis
CRT0044876 is a potent and selective APE1 inhibitor with IC50 of ~3 μM.
价 格:¥电议型 号:T6456产 地:中国大陆
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TN1113Vincetoxicoside BInhibitor,Fungal,ativity,inhibit,Vincetoxicoside B,antifungal
Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.
价 格:¥电议型 号:TN1113产 地:中国大陆
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TN6720Acetylalkannininhibit,antimicrobial,Inhibitor,Alkannin,Isohexenylnaphthazarin,cytotoxic,Acetylalkann
Acetyl alkannin is an isohexenylnaphthazarin pigment isolated from Arnebia euchroma, with antimicrobial and cytotoxic activities.
价 格:¥电议型 号:TN6720产 地:中国大陆
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TN6512TectolHL60,Ftase,Inhibitor,cell,anti-malarial,Parasite,cytotoxic,inhibit,leukemia,drug-resistant,Tec
Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of 3.44±0.20μM. It exhibited significant activity against human leukemia cell lines HL60 and CEM. Tectol may cause itchy dermatitis, the dermatitis appeared on the neck, upper legs, underarms, and trunk area.
价 格:¥电议型 号:TN6512产 地:中国大陆
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T6912NU1025repair,anti-cancer,cytotoxicity,PARP,inhibit,NU-1025,DNA,NU1025,Inhibitor,PAR,Neuroprotective,
NU1025 is a potent PARP inhibitor with IC50 of 400 nM.
价 格:¥电议型 号:T6912产 地:中国大陆
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T9491PyraclostrobinInhibitor,Mitochondrial toxicity,Pyraclostrobin,obesity,Fungal,cardiovascular,Bacteria
Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.
价 格:¥电议型 号:T9491产 地:中国大陆