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TN1493Chrysosplenol Dcancer,Apoptosis,inhibit,ERK1/2,Inhibitor,antitrypanosomal,breast,Chrysosplenol D,ant
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
价 格:¥电议型 号:TN1493产 地:中国大陆
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T10340Antitrypanosomal agent 2Antitrypanosomal agent 2
Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.
价 格:¥电议型 号:T10340产 地:中国大陆
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T10339Antitrypanosomal agent 1
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
价 格:¥电议型 号:T10339产 地:中国大陆
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T10339Antitrypanosomal agent 1Antitrypanosomal agent 1
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
价 格:¥电议型 号:T10339产 地:美洲
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T83014Antitrypanosomal agent 16;化合物 Antitrypanosomal agent 16Antitrypanosomal agent 16
Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T. congolense strain IL3000 [1].
价 格:¥电议型 号:T83014产 地:中国大陆
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T83013Antitrypanosomal agent 17;化合物 Antitrypanosomal agent 17Antitrypanosomal agent 17
Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].
价 格:¥电议型 号:T83013产 地:中国大陆
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T83012Antitrypanosomal agent 18;化合物 Antitrypanosomal agent 18Antitrypanosomal agent 18
Compound 18 (compound 8b), a nitrofuran derivative, exhibits potent in vitro trypanocidal activity, with an IC50 value of 0.03 μM [1].
价 格:¥电议型 号:T83012产 地:中国大陆
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T80929Trypanothione;化合物 TrypanothioneTrypanothione
Trypanothione, a bis-glutathionyl derivative present in trypanosomatids, offers protection against oxidative stress [1] [2] [3].
价 格:¥电议型 号:T80929产 地:中国大陆
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T79316Antitrypanosomal agent 15;化合物 Antitrypanosomal agent 15Antitrypanosomal agent 15
Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4 for T. cruzi and <4 for the human proteasome. It possesses favorable ADME properties, rendering it useful for the study of Chagas disease [1].
价 格:¥电议型 号:T79316产 地:中国大陆
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T79254Antitrypanosomal agent 14;化合物 Antitrypanosomal agent 14Antitrypanosomal agent 14
Antitrypanosomal agent 14 (Compound 1), a potent T. brucei inhibitor with an effective concentration (EC50) of 0.47 μM, also inhibits Tb GSK3 with an inhibitory concentration (IC50) of 12 μM, and is utilized in the research of Human African Trypanosomiasis [1].
价 格:¥电议型 号:T79254产 地:中国大陆
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T78978Antitrypanosomal agent 13;化合物 Antitrypanosomal agent 13Antitrypanosomal agent 13
Compound 4b (antitrypanosomal agent 13) is a potent antitrypanosomal with notable trypanocidal and cytotoxic activities, exhibiting GI50 values of 0.18 μM against T. brucei and 8.4 μM for HL-60 [1].
价 格:¥电议型 号:T78978产 地:中国大陆
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T78977Antitrypanosomal agent 12;化合物 Antitrypanosomal agent 12Antitrypanosomal agent 12
Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.22 μM. It induces faster cell swelling in bloodstream-form trypanosomes compared to Salinomycin [1].
价 格:¥电议型 号:T78977产 地:中国大陆
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T74934Trypanothione synthetase-IN-3;化合物 Trypanothione synthetase-IN-3Trypanothione synthetase-IN-3
Trypanothione Synthetase-IN-3, a mixed noncompetitive inhibitor of Trypanothione Synthetase (TryS) with an inhibition constant (Ki) of 0.8 μM, is useful in researching parasites like L. infantum [1].
价 格:¥电议型 号:T74934产 地:中国大陆
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T74933Trypanothione synthetase-IN-2;化合物 Trypanothione synthetase-IN-2Trypanothione synthetase-IN-2
Trypanothione Synthetase-IN-2 (Compound 3) functions as a competitive inhibitor of Leishmania infantum trypanothione synthetase (TryS), demonstrating an inhibition constant (IC50) of 5.4 μM in the presence of the polyamine S, triamine spermidine [1].
价 格:¥电议型 号:T74933产 地:中国大陆
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T74932Trypanothione synthetase-IN-1;化合物 Trypanothione synthetase-IN-1Trypanothione synthetase-IN-1
Trypanothione Synthetase-IN-1 (Compound 1) serves as a competitive inhibitor of Leishmania infantum trypanothione synthetase (TryS), demonstrating an IC50 value of 14.8 μM in the presence of the polyamine S, triamine spermidine [1].
价 格:¥电议型 号:T74932产 地:中国大陆
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T72267Antitrypanosomal agent 9;化合物 Antitrypanosomal agent 9Antitrypanosomal agent 9
Antitrypanosomal agent 9 is a potent compound with inhibitory activity against T. b. brucei, exhibiting an IC50 of 1.15 μM. It is utilized in research for human African trypanosomiasis (HAT).
价 格:¥电议型 号:T72267产 地:中国大陆
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T72229Antitrypanosomal agent 11;化合物 Antitrypanosomal agent 11Antitrypanosomal agent 11
Antitrypanosomal Agent 11 is a chemical compound effective against Trypanosoma cruzi, exhibiting an inhibition concentration (IC 50) of 0.23 μM.
价 格:¥电议型 号:T72229产 地:中国大陆
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T72228Antitrypanosomal agent 10;化合物 Antitrypanosomal agent 10Antitrypanosomal agent 10
Antitrypanosomal agent 10, an antitrypanosomal compound, effectively inhibits Trypanosoma cruzi with an IC50 of 0.28 μM.
价 格:¥电议型 号:T72228产 地:中国大陆
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T72134Anti-Trypanosoma cruzi agent-4;化合物 Anti-Trypanosoma cruzi agent-4Anti-Trypanosoma cruzi agent-4
Anti-Trypanosoma cruzi Agent-4 is a Trypanosoma cruzi inhibitor utilized for the investigation of infections caused by this parasite.
价 格:¥电议型 号:T72134产 地:中国大陆