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T7132(Rac)-BrassinazoleCytochrome P450,brassinosteroid,(Rac)Brassinazole,triazole-type,CYP90B,CYPs,biosyn
Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. Brassinazole is a triazole-type brassinosteroid biosynthesis inhibitor.
价 格:¥电议型 号:T7132产 地:中国大陆
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T9098DMG-PEG 2000Inhibitor,therapy,T2D,lPEI/DNA nanoparticle,type II diabete,A549,HepG2,inhibit,HeLa,DMG-
DMG-PEG2000 is a lipid excipient that has been used in combination with other lipids in the formation of lipid nanoparticles. Formulations containing DMG-PEG2000 have been used in the development of lipid nanoparticles for the delivery of mRNA-based vaccines.
价 格:¥电议型 号:T9098产 地:中国大陆
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T7626Budipinemonoamine oxidase type B (MAO-B),inhibit,CNS disorders,Parkinson disease,Budipine,Inhibitor,
Budipine is a low affinity, N-methyl-D-aspartate receptor antagonist,is an antiparkinsonian agent.
价 格:¥电议型 号:T7626产 地:中国大陆
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TQ0155Miglustat hydrochlorideN-Butyldeoxynojirimycin,OGT-918,type I gaucher disease,Miglustat,Miglustat hy
Miglustat hydrochloride is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease.
价 格:¥电议型 号:TQ0155产 地:中国大陆
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TN1403Arjunolic acidhepatocyte injury,hyperglycemia,Inhibitor,type 1 diabetes,antimicrobial,antioxidant,Re
Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheimer desease treatment.
价 格:¥电议型 号:TN1403产 地:中国大陆
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T9020GSK620Inhibitor,oral,GSK 620,phenotype,selectivity,GSK-620,whole,anti-inflammatory,GSK620,Epigenetic
GSK620 is a pan-BD2 inhibitor, which shows an anti-inflammatory phenotype in human whole blood with excellent broad selectivity, developability, and in vivo oral pharmacokinetics.GSK620 is highly selective for the BET-BD2 family of proteins, with >200-fold selectivity over all other bromodomains. GSK620 shows an anti-inflammatory phenotype in human whole blood.
价 格:¥电议型 号:T9020产 地:中国大陆
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T13867RH01386RH 01386,βTC6 cells,RH01386,RH-01386,inhibit,Apoptosis,Inhibitor,type 2 diabetes,β cell
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.
价 格:¥电议型 号:T13867产 地:中国大陆
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TP1658LType A Allatostatin I acetateType A Allatostatin I acetate
Type A Allatostatin I acetate is a tridecapeptide. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.
价 格:¥电议型 号:TP1658L产 地:中国大陆
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T6777Bay K 8644Bay K8644,influx,L-type,inhibit,sarcolemmal,Ca2+ channels,(±)-Bay K 8644,Bay K-8644,Bay K
Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM.
价 格:¥电议型 号:T6777产 地:中国大陆
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T8362Benzamidine hydrochlorideurokinase-type ,plasminogen,Threonine proteases,activator,inhibit,factor Xa
Benzamidine HCl is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin (Ki of 35, 350, and 220 μM, respectively).
价 格:¥电议型 号:T8362产 地:中国大陆
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T9246JNJ-63576253TRC-253,mutant,JNJ 63576253,resistant,wild-type,JNJ63576253,TRC 253,prostate,inhibit,And
JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).
价 格:¥电议型 号:T9246产 地:中国大陆
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T9924ObinutuzumabInhibitor,GA 101,Anti-Human CD20 type II, Humanized Antibody,inhibit,GA101,Obinutuzumab,
Obinutuzumab GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.
价 格:¥电议型 号:T9924产 地:中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格:¥电议型 号:T9303产 地:中国大陆
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T6587Mitiglinide CalciumS 21403,Potassium Channel,type,KAD 1229,Mitiglinide Calcium,diabetes,hypoglycaemi
Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.
价 格:¥电议型 号:T6587产 地:中国大陆
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TN7054N-FormylcytisineInhibitor,N-Formylcytisine,inhibit,N Formylcytisine,NFormylcytisine,cytisine-type,al
N-Formylcytisine is a natural product isolated from the stem bark of Maackia amurensis.
价 格:¥电议型 号:TN7054产 地:中国大陆
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TP1187C-Type Natriuretic Peptide (CNP) (1-22), humanseizure syndrome,hypertrophied kidney,C Type Natriuret
C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.
价 格:¥电议型 号:TP1187产 地:中国大陆
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T9022AZD9977AZD9977,Inhibitor,T2DM,AZD-9977,Mineralocorticoid Receptor,Chronic Kidney Disease,?type 2 dia
AZD 9977 is a novel, selective modulator of mineralocorticoid receptor .
价 格:¥电议型 号:T9022产 地:中国大陆
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T8944TTA-A2Pregnane X receptor,TTA-A2,neurological diseases,T-type calcium channel,Inhibitor,Ca2+ channel
TTA-A2 is a selective T-type calcium channel antagonist as a potent anticonvulsant that the Cav3.1 isoform plays a prominent role in mediating. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy.
价 格:¥电议型 号:T8944产 地:中国大陆
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T13173TMPAinhibit,hepatic LO2,AMPKα,TMPA,type II diabetes,AMPK,T cells,Inhibitor,AMP-activated protein kin
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.
价 格:¥电议型 号:T13173产 地:中国大陆
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T8674SR33805Ca channels,channel,failing,Ca2+ channels,Ca2+,SR 33805,Calcium Channel,acute,L-type,SR-33805
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)
价 格:¥电议型 号:T8674产 地:中国大陆