T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in

AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.

价 格：￥电议型 号：T9041产 地：中国大陆

T6476Dofetilidecardiovascular,potent,specific,class,antiarrhythmic,orally,Inhibitor,UK68789,UK-68789,Dofe

Dofetilide is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter.

价 格：￥电议型 号：T6476产 地：中国大陆

T9177BPAM344Ionotropic glutamate receptors,GluK3a,PAM,iGluR,BPAM344,BPAM 344,Inhibitor,BPAM-344,KAR,GluK1

BPAM344 is a potent positive allosteric modulator (PAM) of the KAR subunits GluK1b, GluK2a, and GluK3a.

价 格：￥电议型 号：T9177产 地：中国大陆

TN1121EvocarpineEvocarpine,Ca2+,HL-60,inhibit,antimycobacterial,Inhibitor,leukaemia,Bacterial,Apoptosis,In

Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.

价 格：￥电议型 号：TN1121产 地：中国大陆

T8003Methotrexate disodiumDNA/RNA Synthesis,WR19039 disodium,DNA,leukemia,immunosuppressant,reductase,ADC

Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor

价 格：￥电议型 号：T8003产 地：中国大陆

TJS0328Nordalberginpromyelocytic,Inhibitor,coumarin,HL-60,cells,leukemia,differentiation,Nordalbergin,inhib

价 格：￥电议型 号：TJS0328产 地：中国大陆

T6588Mitoxantroneleukaemia,NSC301739,PKC,MCF-7,NSC 301739,lymphocytes,Topoisomerase,Mitoxantrone,HL60 cel

Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.

价 格：￥电议型 号：T6588产 地：中国大陆

T7649Tyrphostin A1Tyrphostin A 1,Interleukin Related,AG 9,Tyrphostin1,Tyrphostin A1,inhibit,Tyrphostin A-

Tyrphostin A1 is an inhibitor of EGFR tyrosine kinase .

价 格：￥电议型 号：T7649产 地：中国大陆

T9014SKI-178resistant,SphK,cytotoxic,myeloid,Inhibitor,Apoptosis,leukemia,multi-drug,inhibit,SKI-178,canc

SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during prolonged mitosis, mediated by SKI-178 leads to the simultaneous phosphorylation of the prosurvival Bcl-2 family members, Bcl-2 and Bcl-xl, as well as the phosphorylation and subsequent degradation of Mcl-1.

价 格：￥电议型 号：T9014产 地：中国大陆

T7200TAK-960Polo-like Kinase (PLK),cell,cancer,proliferation,Inhibitor,mitosis,TAK960,TAK 960,leukemia,in

TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.

价 格：￥电议型 号：T7200产 地：中国大陆

TN4379Kansuinine AInterleukin Related,inhibit,Kansuinine A,Inhibitor

Kansuinine A, a 95% ethanol extract from the roots of E. kansui, possesses an inhibitory effect on IL-6-induced Stat3 activation by activating ERK1/2.

价 格：￥电议型 号：TN4379产 地：中国大陆

T8280Deacetylasperulosidic Acidinhibit,Inhibitor,Deacetylasperulosidic Acid,Interleukin Related

Deacetylasperulosidic acid is a natural compound of Morinda citrifolia fruit. It has antioxidant activity by increasing superoxide dismutase activity. It also prevents 4-nitroquinoline 1-oxide (4NQO) induced DNA damage in vitro, suppresses IL-2 production along with the activation of natural killer cells.

价 格：￥电议型 号：T8280产 地：中国大陆

TP1422Interleukin (IL)-6 ReceptorInterleukin (IL) 6 Receptor,Interleukin (IL)6 Receptor

Interleukin (IL)-6 Receptor is a peptide.

价 格：￥电议型 号：TP1422产 地：中国大陆

T7007UNC2025Inhibitor,inhibit,FLT3,leukemia,CD135,Fms like tyrosine kinase 3,acute,Cluster of differentia

UNC-2025（ IC50 of 0.74 nM and 0.8 nM） is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.

价 格：￥电议型 号：T7007产 地：中国大陆

T9715AplidineInhibitor,DNA/RNA Synthesis,MOLT-4,SARS coronavirus,infection,SARS-CoV,Plitidepsin,Leukemia,

Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80?nM).

价 格：￥电议型 号：T9715产 地：中国大陆

T8867RO2959 HydrochlorideIP3,SOCE,Ca2+ release-activated Ca2+ channels,RO2959 Hydrochloride,Interleukin R

RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.

价 格：￥电议型 号：T8867产 地：中国大陆

T91492BActpermeable,primary,inhibit,Eukaryotic Initiation Factor (eIF),2BAct,stress,defects,response,fibr

2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response

价 格：￥电议型 号：T9149产 地：中国大陆

T8308NL-1Inhibitor,viability,Mitochondrial Metabolism,leukemia,NL-1,CISD1,NL1,antileukemic,MitoNEET,lymph

NL-1 is a mitoNEET inhibitor with antileukemic effect.

价 格：￥电议型 号：T8308产 地：中国大陆

TN7148Mukanadin C

Mukanadin C is a marine derived natural products found in Stylissa carteri.

价 格：￥电议型 号：TN7148产 地：中国大陆

T8192Pentacosanoic acidesters,fatty,Endogenous Metabolite,adrenoleukodystrophy,Inhibitor,cholesterol,acid

Pentacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids.

价 格：￥电议型 号：T8192产 地：中国大陆