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T7007UNC2025Inhibitor,inhibit,FLT3,leukemia,CD135,Fms like tyrosine kinase 3,acute,Cluster of differentia
UNC-2025( IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
价 格:¥电议型 号:T7007产 地:中国大陆
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T4419UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
价 格:¥电议型 号:T4419产 地:中国大陆
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T7007UNC2025化合物UNC2025mrx-6313|||UNC-2025|||UNC 2025
UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
价 格:¥电议型 号:T7007产 地:中国大陆
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T4419UNC2025 2HCl (1429881-91-3(free base));化合物UNC2025 2HClUNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.
价 格:¥电议型 号:T4419产 地:中国大陆
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T39474UNC2025 hydrochlorideUNC2025 hydrochlorideUNC2025 hydrochloride
UNC2025 hydrochloride is a potent, ATP-competitive, highly orally active Mer/Flt3 inhibitor. It has IC50 values of 0.74 nM and 0.8 nM, respectively, for Mer and Flt3. UNC2025 hydrochloride demonstrates over 45-fold selectivity for MERTK compared to Axl (IC50 = 122 nM; Ki = 13.3 nM). Additionally, UNC2025 hydrochloride exhibits excellent PK properties, making it suitable for investigating acute leukemia.
价 格:¥电议型 号:T39474产 地:中国大陆