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T29114VRT-532
VRT-532 is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag) in cystic fibrosis, and modification of CFTR by small molecule modulator VRT-532 can increase ARSB and reduce the accumulation of 4-chondroitin sulfate.
价 格：￥电议型 号：T29114产 地：中国大陆
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T7005UlixertinibERK,VRT 752271,Ulixertinib,inhibit,VRT-752271,BVD 523,BVD523,Inhibitor,Extracellular sign
Ulixertinib (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.
价 格：￥电议型 号：T7005产 地：中国大陆
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T4084SibofimlocAntibiotic-202；VRT-1353385；Antibiotic 202
Antibiotic-202, an antibiotic compound, is used in treating bacterial infections.
价 格：￥电议型 号：T4084产 地：中国大陆
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T2636DecernotinibVRT-831509；VX-509
Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
价 格：￥电议型 号：T2636产 地：中国大陆
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T2595Lumacaftor鲁玛卡托；VRT 826809；VX-809
VX-809 is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
价 格：￥电议型 号：T2595产 地：中国大陆
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T2595LumacaftorLumacaftor,VRT 826809,VX-809
VX-809 is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
价 格：￥电议型 号：T2595产 地：美洲
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T2636DecernotinibDecernotinib,VRT-831509,VX-509
Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
价 格：￥电议型 号：T2636产 地：美洲
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T80852VRT-534；化合物 VRT-534VRT-534
VRT-534 is a compound that selectively targets connexin 26 (Cx26), demonstrating dose-responsive binding to both wild-type (WT) Cx26 and the mutant Cx26 K188N, with EC50 values of 19 μM and 5 μM, respectively. It has potential applications in research concerning hearing impairment [1].
价 格：￥电议型 号：T80852产 地：中国大陆
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T72907Ac-SVVVRT-NH2；化合物 Ac-SVVVRT-NH2Ac-SVVVRT-NH2
Ac-SVVVRT-NH2, a PGC-1α modulator, enhances the activity of the human PGC-1α promoter (114%), elevates PGC-1α mRNA levels (125%), and promotes intracellular lipid accumulation (128%) in subcutaneous human adipocytes. This compound has potential applications in research related to diseases influenced by PGC-1α.
价 格：￥电议型 号：T72907产 地：中国大陆
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T7005LUlixertinib hydrochloride化合物 T7005LUlixertinib HCl|||BVD-523|||VRT752271|||BVD 523|||BVD523|||VRT 75
Ulixertinib is an inhibitor of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival.
价 格：￥电议型 号：T7005L产 地：中国大陆
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T7005Ulixertinib；优立替尼BVD-523|||VRT752271；BVD-523|||VRT752271|||优立替尼
Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2.
价 格：￥电议型 号：T7005产 地：中国大陆
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T69632VRT-043198；化合物 VRT-043198VRT-043198
VRT-043198, the drug metabolite of VX-765 (Belnacasan), is a potent, selective, and blood-brain barrier permeable inhibitor of the interleukin-converting enzyme/caspase-1 subfamily caspases, displaying Ki values of 0.8 nM for ICE/caspase-1 and 0.6 nM for caspase-4, respectively.
价 格：￥电议型 号：T69632产 地：中国大陆
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T4084Sibofimloc；化合物Antibiotic-202VRT-1353385|||Antibiotic-202|||Antibiotic 202；VRT-1353385|||Antibiotic-2
Sibofimloc (Antibiotic-202), an antibiotic compound, is used in treating bacterial infections.
价 格：￥电议型 号：T4084产 地：中国大陆
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T35074VRT-325；化合物VRT-325CFcor 325|||VRT-534|||CFcor325|||VRT 325|||VRT325|||CF-106951|||CFcor-325；CFcor 32
VRT-325 can repair folding defects by promoting dimerization of the two NBDs or by promoting folding of the TMD.VRT-325 accelerates the healing rate of CF cell monolayers.
价 格：￥电议型 号：T35074产 地：中国大陆
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T35073VRT-18858；化合物 T35073VRT 18858；VRT 18858
VRT-18858 is a metabolite of VX-740.
价 格：￥电议型 号：T35073产 地：中国大陆
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T29114VRT-532；化合物VRT-532CFpot-532|||CFpot-532)；CFpot-532|||CFpot-532)
VRT-532 (CFpot-532) is an effective modulator of CFTR and is commonly used in studies of cystic fibrosis (CF) caused by CFTR defects. Arylsulfatase B (ARSB), which is necessary to reduce the accumulation of sulphate glycosaminosaccharide (gag) in cystic fibrosis, and modification of CFTR by small molecule modulator VRT-532 can increase ARSB and reduce the accumulation of 4-chondroitin sulfate.
价 格：￥电议型 号：T29114产 地：中国大陆
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T2636Decernotinib；化合物DecernotinibVX-509|||VRT-831509；VX-509|||VRT-831509
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
价 格：￥电议型 号：T2636产 地：中国大陆
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T2595Lumacaftor；鲁玛卡托VX-809|||VRT 826809；鲁玛卡托|||VX-809|||VRT 826809
Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM).
价 格：￥电议型 号：T2595产 地：中国大陆
