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产品数：86101
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T8722iKIX1antifungal,Inhibitor,drug-resistant,Fungal,CgGal11A,CgPdr1,infection,C. glabrata,iKIX1,inhibit,
iKIX1 is an Pdr1-dependent gene activation. It re-sensitizes drug-resistant C. glabrata to azole antifungals in vitro and in animal models for disseminated and urinary tract C. glabrata infection.
价 格：￥电议型 号：T8722产 地：中国大陆
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T9683VX-150Na+ channels,VX-150,indications,Inhibitor,Na channels,orally,inhibit,pain,VX 150,VX150,Sodium
VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).
价 格：￥电议型 号：T9683产 地：中国大陆
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T7882Indomethacin farnesilAutophagy,inhibit,flux,Inhibitor,Indomethacin farnesil,cox1,COX,pain,Cyclooxyge
Infree is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
价 格：￥电议型 号：T7882产 地：中国大陆
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TP1970LProsaptide TX14(A) acetateProsaptide TX14(A) acetate,Prosaptide TX-14(A) acetate
Prosaptide TX14(A) acetate is a potent GPR37L1 and GPR37 agonist. Prosaptide Tx14(A) TFA increases both ERK1 and ERK2 phosphorylation in Schwann cells.
价 格：￥电议型 号：TP1970L产 地：中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格：￥电议型 号：T9072产 地：中国大陆
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T7768RGX-104RGX 104,inhibit,LXR,RGX-104,Liver X receptor,RGX104,Inhibitor
RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR)
价 格：￥电议型 号：T7768产 地：中国大陆
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T9430Venadaparibinhibit,PARP,Venadaparib,IDX1197,Inhibitor,solid,IDX 1197,tumors,anticancer,poly ADP ribo
Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib is insensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSBs) and can be used in solid tumor research.
价 格：￥电议型 号：T9430产 地：中国大陆
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T9567Samatasvirinhibit,IDX18719,HCV,Samatasvir,IDX-719,infectious,IDX 719,IDX 18719,replication,antiviral
Samatasvir is a pan-genotypic inhibitor of the HCV non-structural protein 5A.
价 格：￥电议型 号：T9567产 地：中国大陆
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T24182ISX-1ISX1
ISX-1 inhibits adipogenesis and promotes osteoblastogenesis. ISX-1 can be used in studies about osteoporosis and osteopenia.
价 格：￥电议型 号：T24182产 地：中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格：￥电议型 号：T9303产 地：中国大陆
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TQ0237LemborexantLemborexant,OX1R,Orexin Receptor (OX Receptor),CNS,competitive,inhibit,CYP3A4,E2006,Hypoc
Lemborexant is a reversible and orally active dual antagonist of the orexin OX1 and OX2 receptors (IC50s: 6.1 nM and 2.6 nM).
价 格：￥电议型 号：TQ0237产 地：中国大陆
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T6545IOX1Inhibitor,inhibit,IOX 1,IOX-1,Histone Demethylase,IOX1
IOX1 is the most effective broad-spectrum 2OG oxygenases(including the JmjC demethylases) inhibitor. The IC50 of IOX1 for KDM4A, KDM3A, is 0.6 and 0.1 uM, respectively.
价 格：￥电议型 号：T6545产 地：中国大陆
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T6574LumiracoxibCyclooxygenase,Inhibitor,bone cancer,osteoarthritis,inflammatory,COX189,inhibit,hyperalge
Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
价 格：￥电议型 号：T6574产 地：中国大陆
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T60031NRX-1933inhibit,NRX-1933,NRX1933,Inhibitor,NRX 1933
NRX-1933 is a molecular glue and enhances the interaction between an oncogenic transcription factor, β-Catenin, and its cognate E3 ligase, SCFβ-TrCP.
价 格：￥电议型 号：T60031产 地：中国大陆
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T7281F-15599NLX-101,inhibit,5-HT Receptor,Serotonin Receptor,NLX 101,F-15599,NLX101,F15599,F 15599,5-hydr
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).
价 格：￥电议型 号：T7281产 地：中国大陆
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T6839FRAX1036FRAX 1036,Inhibitor,p21 activated kinases,PAK,FRAX1036,inhibit,FRAX-1036
FRAX-1036 is a effective and selective PAK1 inhibitor.
价 格：￥电议型 号：T6839产 地：中国大陆
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T8408GKT136901peroxynitrite,scavenger,neurodegeneration,NOX1/4,NADPH,oxidase,inhibit,NOX,NADPH Oxidase,GK
GKT136901 is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
价 格：￥电议型 号：T8408产 地：中国大陆
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TQ0032RosiptorAQX1125,Rosiptor,Phosphatase,AQX 1125,Inhibitor,inhibit
Rosiptor (AQX-1125) is an orally-active and specific phosphatase SHIP1 activator with anti-inflammatory effects.
价 格：￥电议型 号：TQ0032产 地：中国大陆
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T8984FLTX1cancer,Estrogen Receptor/ERR,FLTX1,FLTX 1,Inhibitor,fluorescent,Tamoxifen,antiestrogenic,inhibi
FLTX1, a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus.
价 格：￥电议型 号：T8984产 地：中国大陆
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T6275Obatoclax MesylateObatoclax；GX15-070；奥巴克拉盐酸盐
Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.
价 格：￥电议型 号：T6275产 地：中国大陆
