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T6816DASA-58DASA58,inhibit,Inhibitor,DASA 58,DASA-58,glycolysis,TXNIP,cancer metabolism,Pyruvate Kinase,p
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.
价 格:¥电议型 号:T6816产 地:中国大陆
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T13230TXNIP-IN-1
TXNIP-IN-1 is an inhibitor of the TXNIP-TRX complex and used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease.
价 格:¥电议型 号:T13230产 地:中国大陆
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T11174(R)-ElagolixNBI-56418;恶拉戈利
(R)-Elagolix is a short-acting, nonpeptide, GnRH antagonist with an IC50 and Ki of 0.25 and 3.7 nM, respectively. administered orally, that unlike injectable depot GnRH agonists and antagonists, produces a dose-dependent suppression of ovarian estrogen pr
价 格:¥电议型 号:T11174产 地:中国大陆
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T12189NBDHEXNBDHEX
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
价 格:¥电议型 号:T12189产 地:美洲
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T13294Veledimex (S entiomer)Veledimex (S entiomer),Veledimex (S enantiomer),INXN-1001 S enantiome
Veledimex S enantiomer is the S enantiomer of veledimex. Veledimex is an oral activator ligand for a proprietary gene therapy promoter system and CYP3A4/5 inhibitor .
价 格:¥电议型 号:T13294产 地:美洲
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T2101NavitoclaxNavitoclax,ABT-263,
Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2, Bcl-xL, and Bcl-W (Ki < 1 nM for all three proteins).
价 格:¥电议型 号:T2101产 地:美洲
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T5325NifurtimoxNifurtimox,BAY-2502,BAY-A-2502
Nifurtimox is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi epimastigotes, respectively).
价 格:¥电议型 号:T5325产 地:美洲
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T5678N-(2-Aminoethyl)-5-chlor-2-pyridincarboxN-(2-Aminoethyl)-5-chlor-2-pyridincarbox,Lazabemide hydrochl
N-(2-Aminoethyl)-5-chlor-2-pyridincarbox is a reversible and selective mao-b inhibitor(Ki:7.9nM).
价 格:¥电议型 号:T5678产 地:美洲
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T82409Fepixnebart;化合物 FepixnebartFepixnebart
Fepixnebart is a humanized IgG4κ antibody that targets TGF-alpha (TGFA).
价 格:¥电议型 号:T82409产 地:中国大陆
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T78295Samalizumab;沙马组单抗ALXN 6000;ALXN 6000
Samalizumab (ALXN 6000), a humanized monoclonal antibody, selectively targets and inhibits the interaction between CD200 and its receptor (CD200R). This compound is utilized in the research of multiple myeloma and B-cell chronic lymphocytic leukemia [1].
价 格:¥电议型 号:T78295产 地:中国大陆
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T76867Ravulizumab;雷夫利珠单抗ALXN1210;ALXN1210
Ravulizumab (ALXN1210) is a humanized monoclonal antibody targeting complement factor 5 that specifically binds to human complement protein C5 with high affinity to block complement activation. Ravulizumab can be used for the prevention and treatment of paroxysmal sleep hemoglobinuria, atypical hemolytic uremic syndrome and myasthenia gravis.
价 格:¥电议型 号:T76867产 地:中国大陆
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T75401D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP);化合物 D-galactosyl-β1-3-N-acetyl-
D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP), belonging to the CAZy glycoside hydrolase family GH112, plays a pivotal role in biochemical research. This enzyme catalyzes the phosphorolysis of lacto-n-biose and galacto-n-biose, yielding Gal-1-P and the corresponding N-acetyl-D-hexosamine [1].
价 格:¥电议型 号:T75401产 地:中国大陆
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T71164CXN37378;化合物 CXN37378CXN37378
CXN37378, also known as NAP, is a potent and selective antagonist for the μ-opioid receptor (MOR). This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).
价 格:¥电议型 号:T71164产 地:中国大陆
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T71155NP-1815-PX;化合物 NP-1815-PXNP-1815-PX
NP-1815-PX is a selective P2X4R antagonist with demonstrated anti-inflammatory effects and the capability to alleviate pain in chronic pain models. Additionally, it impedes contractions of guinea pig tracheal and bronchial smooth muscle (TSM and BSM)[1][2][3].
价 格:¥电议型 号:T71155产 地:中国大陆
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T68327Dexnafenodone Free Base;化合物 Dexnafenodone Free BaseDexnafenodone Free Base
Dexnafenodone Free Base is a potent inhibitor of noradrenaline, and to a lesser degree of serotonin reuptake, induced changes in the pattern of sleep which are comparable to those of non‐sedating tricyclic antidepressants.
价 格:¥电议型 号:T68327产 地:中国大陆
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T68110Moxnidazole;吗硝唑Moxnidazole
Moxnidazole, a 5-nitroimidazole, is mutagenic in microbial assays and in Drosophila, inducing genetic alterations in mouse somatic cells.
价 格:¥电议型 号:T68110产 地:中国大陆
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T61619XN methyl pyrazole;化合物 XN methyl pyrazoleXN methyl pyrazole
XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1].
价 格:¥电议型 号:T61619产 地:中国大陆
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T41281N-Methylprotoporphyrin IX;化合物 N-Methylprotoporphyrin IXN-Methylprotoporphyrin IX
N-Methylprotoporphyrin IX is a potent ferrochelatase enzyme inhibitor[1].
价 格:¥电议型 号:T41281产 地:中国大陆
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T39740Acoramidis hydrochloride;盐酸橡酰胺AG10 hydrochloride|||Alxn2060 hydrochloride;AG10 hydrochloride|||Alxn2
Acoramidis hydrochloride (Alxn2060 hydrochloride) is an orally active and selective kinetic stabilizer of WT and V122I- TTR (transthyretin) . Acoramidis hydrochloride is used in the study for transthyretin amyloidosis.
价 格:¥电议型 号:T39740产 地:中国大陆
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T39493VemircopanVemircopanACH0145228|||ACH-5228|||ALXN2050
Vemircopan is a complement factor D inhibitor.
价 格:¥电议型 号:T39493产 地:中国大陆