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T6446ClevudineOrthopoxvirus,half-life,nucleoside,DNA/RNA Synthesis,analog,Inhibitor,polymerase,Hepatitis
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DN
价 格：￥电议型 号：T6446产 地：中国大陆
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T7142Cephalosporin C zinc saltInhibitor,Orthopoxvirus,Cephalosporin C zinc salt,Bacterial,inhibit,Cephalo
Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM), and this inhibition was largely attributable to the presence of zinc.
价 格：￥电议型 号：T7142产 地：中国大陆
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T7655FialuridineFialuridine,NSC678514,DRG 0098,Orthopoxvirus,DNA/RNA Synthesis,DRG0098,inhibit,NSC 678514
Fialuridine is a DNA-directed DNA polymerase inhibitor potentially for the treatment of HBV infection with potent activity against hepatitis B virus in vitro and in vivo.
价 格：￥电议型 号：T7655产 地：中国大陆
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T6567LevofloxacinOrthopoxvirus,Levofloxacin,BK Viremia,Topoisomerase,inhibit,Inhibitor,Antibiotic,DNA gyr
Levofloxacin is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
价 格：￥电议型 号：T6567产 地：中国大陆
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T3385Gypenoside XVII七叶胆苷XVII；Gynosaponin S；GP-17
Gypenoside XVII confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3β pathways.
价 格：￥电议型 号：T3385产 地：中国大陆
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T2668JNK-IN-8JNK Inhibitor XVI
JNK-IN-8 is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.
价 格：￥电议型 号：T2668产 地：中国大陆
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T2668JNK-IN-8JNK-IN-8,JNK Inhibitor XVI,
JNK-IN-8 is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.
价 格：￥电议型 号：T2668产 地：美洲
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T80661Antihypertensive sulfonanilide XVII；抗高血压剂XVIIAntihypertensive sulfonanilide XVII
Antihypertensive sulfonanilide XVII is an orally available antihypertensive sulfonanilide small molecule compound for the study of hypertension.
价 格：￥电议型 号：T80661产 地：中国大陆
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T75792Huwentoxin XVI TFA；化合物 Huwentoxin XVI TFAHuwentoxin XVI TFA
Huwentoxin XVI TFA, a potent analgesic derived from the Chinese tarantula Ornithoctonus huwena, acts as a highly reversible and selective antagonist of mammalian N-type calcium channels (IC 50 of ~60 nM), with no impact on voltage-gated T-type calcium channels, potassium channels, or sodium channels [1].
价 格：￥电议型 号：T75792产 地：中国大陆
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T63050JH-XVII-10；化合物 JH-XVII-10JH-XVII-10
JH-XVII-10 is a selective, orally active and potent inhibitor of DYRK1A (IC50: 3 nM) and DYRK1B (IC50: 5 nM).JH-XVII-10 exhibits antitumor effects in squamous cell carcinoma of the neck (HNSCC) cell lines.
价 格：￥电议型 号：T63050产 地：中国大陆
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T40280JH-XVI-178；JH-XVI-178JH-XVI-178
JH-XVI-178 is a highly potent and selective CDK8/19 inhibitor with favorable pharmacokinetic attributes, including low clearance and moderate oral bioavailability.
价 格：￥电议型 号：T40280产 地：中国大陆
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T35556GSK-3β inhibitor 8；GSK-3β抑制剂8GSK3β Inhibitor XVIII；GSK3β Inhibitor XVIII
GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine derivative that negatively regulates the Wnt signaling pathway and stimulates β-cell proliferation.
价 格：￥电议型 号：T35556产 地：中国大陆
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T3385Gypenoside XVII；七叶胆苷XVIIGP-17|||Gynosaponin S；GP-17|||Gynosaponin S|||七叶胆苷XVII
Gypenoside XVII (Gynosaponin S) confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3β pathways.
价 格：￥电议型 号：T3385产 地：中国大陆
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T2668JNK-IN-8；化合物JNK-IN-8JNK Inhibitor XVI；JNK Inhibitor XVI
JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM). The selectivity is higher 10-fold than MNK2, Fms and no inhibition of Met, c-Kit, PDGFRβ in A375 cell line.
价 格：￥电议型 号：T2668产 地：中国大陆
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T124360Grayanotoxin XVIII；化合物 Grayanotoxin XVIIIGrayanotoxin XVIII
Grayanotoxin XVIII is a useful organic compound for research related to life sciences. The catalog number is T124360 and the CAS number is 70474-76-9.
价 格：￥电议型 号：T124360产 地：中国大陆
