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T9343N-Cbz-DL-tryptophanNCbzDLtryptophan,N Cbz DL tryptophan
N-Cbz-DL-tryptophan is a cholecystokinin receptor antagonist, abolished the response of the isolated heart to CCK-8.
价 格:¥电议型 号:T9343产 地:中国大陆
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TP1263Fz7-21lipid-binding groove,FZD7,Wnt,Fz7 21,Wnt–β-catenin,Fz-7-21,conformation,FZD7 CRD,intestinal or
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
价 格:¥电议型 号:TP1263产 地:中国大陆
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T9023AtuliflaponInhibitor,inhibit,FLAP,AZD-5718,AZD 5718,artery,Atuliflapon,disease,Coronary,5-LO activat
AZD5718 is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease.
价 格:¥电议型 号:T9023产 地:中国大陆
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T10436AZD4573AZD 4573,inhibit,CDK,AZD4573,AZD-4573,Inhibitor,Cyclin dependent kinase
AZD4573 is an effective and selective CDK9 inhibitor (IC50: <4 nM). It enables transient target engagement for the treatment of hematologic malignancies.
价 格:¥电议型 号:T10436产 地:中国大陆
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T9756AZD-9574PPAR,Peroxisome proliferator-activated receptors,breast cancer,inhibit,AZD-9574,HRR,HRR-defi
AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs. AZD-9574 exhibits anti-cancer activities and can be used in studies about HRD+ breast cancer and advanced solid malignancies.
价 格:¥电议型 号:T9756产 地:中国大陆
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T6771AZD3264inhibit,I kappa B kinase,IκB kinase,AZD 3264,AZD-3264,AZD3264,IKK,Inhibitor
AZD3264 is a new type IKK2 inhibitor.
价 格:¥电议型 号:T6771产 地:中国大陆
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T64378AZD0095AZD0095
AZD0095 is a selective inhibitor of MCT4?with an IC50 of 1.3 nM.
价 格:¥电议型 号:T64378产 地:中国大陆
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T14387AZD9898AZD-9898,AZD9898
AZD9898 is an inhibitor of leukotriene-C4 synthetase with an IC50 of 0.28 nM. AZD9898 can be used in studies about asthma. AZD9898 mitigates the GABA binding and hepatic toxicity signal.
价 格:¥电议型 号:T14387产 地:中国大陆
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T36200AZD 3147AZD 3147
AZD 3147 is an inhibitor of mTORC with IC50s of 40.7 and 5.75 nM for mTORC1 and mTORC2. AZD 3147 shows IC50s of 912, 5495, 9333, and 6310 nM for PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively.
价 格:¥电议型 号:T36200产 地:中国大陆
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T7122AZD-7648DNA-dependent protein kinase,inhibit,Apoptosis,AZD7648,A549,OAW42,PI3K,Inhibitor,Phosphoinos
AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.
价 格:¥电议型 号:T7122产 地:中国大陆
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TQ0038BrensocatibDipeptidyl Peptidase,DPP,AZD 7986,inhibit,INS-1007,AZD-7986,Brensocatib,INS1007,Inhibitor
AZD7986 is a Dipeptidyl peptidase 1 (DPP1) inhibitor (pIC50s: 6.85, 7.7, 7.6, 7.8, and 7.8 in human, rat, mouse, rabbit, and dog, respectively).
价 格:¥电议型 号:TQ0038产 地:中国大陆
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TQ0225VelsecoratAZD 7594,Inhibitor,AZD-7594,Velsecorat,Glucocorticoid Receptor,AZ-13189620,AZ 13189620,inh
AZD7594 is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM).
价 格:¥电议型 号:TQ0225产 地:中国大陆
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T8751AZD8931 diFuMaric acidAZD8931 diFuMaric acid,AZD-8931 diFuMaric acid
AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).
价 格:¥电议型 号:T8751产 地:中国大陆
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T7516ZD7288inhibit,ICI D-7288,Hyperpolarization activated cyclic nucleotide gated channels,ICI D 7288,ZD
ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity.
价 格:¥电议型 号:T7516产 地:中国大陆
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T6632RaltitrexedRaltitrexed,Thymidylate Synthase,D 1694,inhibit,Nucleoside Antimetabolite/Analog,ZD-1694,
Raltitrexed(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.
价 格:¥电议型 号:T6632产 地:中国大陆
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T30260AZD-5672
AZD-5672 is an antagonist of CCR5 with an IC50 of 0.32 nM. AZD-5672 inhibits hERG cardiac ion channel binding and P-gp-mediated digoxin transport with IC50s of 7.3 μM and 32 μM. AZD-5672 can be used in studies about rheumatoid arthritis.
价 格:¥电议型 号:T30260产 地:中国大陆
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T6399AZD1981Prostaglandin Receptor,AZD 1981,AZD1981,Inhibitor,AZD-1981,inhibit
AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. AZD1981 has been used in trials studying the treatment and basic science of Asthma, Postmenopausal, Pharmakokinetic, Asthma Patients, and Drug Interaction, among others.
价 格:¥电议型 号:T6399产 地:中国大陆
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T6773AZD8186Phosphoinositide 3-kinase,inhibit,AZD-8186,AZD8186,PI3K,Inhibitor,AZD 8186
AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).
价 格:¥电议型 号:T6773产 地:中国大陆
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T7136AZD-6280γ-Aminobutyric acid Receptor,GABA Receptor,inhibit,Gamma-aminobutyric acid Receptor,AZD6280,
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
价 格:¥电议型 号:T7136产 地:中国大陆
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T9022AZD9977AZD9977,Inhibitor,T2DM,AZD-9977,Mineralocorticoid Receptor,Chronic Kidney Disease,?type 2 dia
AZD 9977 is a novel, selective modulator of mineralocorticoid receptor .
价 格:¥电议型 号:T9022产 地:中国大陆