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T80742Zelavespib hydrochloride;化合物 Zelavespib hydrochloridePU-H71 hydrochloride;PU-H71 hydrochloride
Zelavespib (PU-H71) hydrochloride is a potent inhibitor of Hsp90, exhibiting an IC50 value of 51 nM in MDA-MB-468 cells.
价 格:¥电议型 号:T80742产 地:中国大陆
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T6960LPU-H71 HCl;PU-H71盐酸盐PU-H71 HCl(873436-91-0 Free base)|||Zelavespib HCl;PU-H71 HCl(873436-91-0 Free b
PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of malignancy. PU-H71 HCL has an inhibitory effect on the protein expression levels of Rad51 and Ku70, which may be associated with the double chain break repair in the homologous recombination pathway and non-homologous end-joining pathway.
价 格:¥电议型 号:T6960L产 地:中国大陆