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  • T0782BenzthiazideAquatag;Dihydrex;Lemazide;苄噻嗪

    Benzthiazide is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause l

    价 格:¥电议型 号:T0782产 地:中国大陆

  • T35475aTAG 4531;aTAG 4531aTAG 4531

    Degrader of MTH1 fusion proteins for use within the aTAG system. Comprises a ligand selective for MTH1, a linker and the cereblon-binding ligand Thalidomide . Induces highly potent and selective degradation of fusion proteins after a 4 h incubation (DC50 = 0.34 nM; Dmax = 93.14%). Cell-permeable. Suitable for in vitro and in vivo applications. Mouse DMPK properties are provided in the supplementary file (see below). (MTH1 can be expressed as a fusion with a target protein of interest using genom

    价 格:¥电议型 号:T35475产 地:中国大陆

  • T35474aTAG 2139;aTAG 2139aTAG 2139

    Degrader of MTH1 fusion proteins for use within the aTAG system. Comprises a ligand selective for MTH1, a linker and the cereblon-binding ligand Thalidomide . Induces highly potent and selective degradation of fusion proteins after a 4 h incubation (DC50 = 0.27 nM; Dmax = 92.1%). Cell-permeable. Suitable for in vitro and in vivo applications. Mouse DMPK properties are provided in the supplementary file (see below). (MTH1 can be expressed as a fusion with a target protein of interest using genome

    价 格:¥电议型 号:T35474产 地:中国大陆

  • T30188L1(Iso)-Atagabalin HCl;异构体Atagabalin盐酸盐(Iso)-Atagabalin HCl((Iso)-223445-75-8);(Iso)-Atagabalin HCl((I

    (Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.

    价 格:¥电议型 号:T30188L1产 地:中国大陆

  • T30188LAtagabalin HCl;Atagabalin盐酸盐PD-0200390 HCl|||Atagabalin HCl(223445-75-8 Free base);PD-0200390 HCl|||

    Atagabalin HCl is a novel voltage-dependent calcium channel (VDCC) α2δ subunit (1 and 2) ligand that affects slow-wave sleep and can be used to treat insomnia.

    价 格:¥电议型 号:T30188L产 地:中国大陆

  • T30188Atagabalin;化合物 T30188PD 0200390|||PD-0200390|||PD0200390;PD 0200390|||PD-0200390|||PD0200390

    Atagabalin, also known as PD 0200390, is a gabamimetic agent under development for the treatment for insomnia. Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2). It was discontinued following unsatisfactory trial results.

    价 格:¥电议型 号:T30188产 地:中国大陆

  • T0782Benzthiazide;苄噻嗪Aquatag|||Lemazide|||Dihydrex;Aquatag|||苄噻嗪|||Lemazide|||Dihydrex

    Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-r

    价 格:¥电议型 号:T0782产 地:中国大陆

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