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T79633Antileishmanial agent-22;化合物 Antileishmanial agent-22Antileishmanial agent-22
Antileishmanial agent-22 (compound 15b) serves as an antiparasitic and antibacterial, exhibiting activities against Leishmania (IC50 = 0.408 μM), malaria, and tuberculosis. It operates on an antifolate mechanism, suppressing both folic and folinic acids with 88% and 94% efficacy at 100 μM, respectively. This compound also demonstrates a 96.67% inhibitory effect on P. berghei in vivo/in vitro at 48.4 μM/kg/day and 0.038 μM (IC50), and it inhibits M. tuberculosis with an MIC of 28.44 μM [1].
价 格:¥电议型 号:T79633产 地:中国大陆
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T79468Antimicrobial agent-22;化合物 Antimicrobial agent-22Antimicrobial agent-22
Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties [1].
价 格:¥电议型 号:T79468产 地:中国大陆
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T63755Antitubercular agent-22;化合物 Antitubercular agent-22Antitubercular agent-22
Antitubercular agent-22 (Compound 2) is an effective anti-Candida and anti-tuberculosis agent against Candida albicans MTCC 3017 (MIC: 2.34 μg/ml) and M. tuberculosis (H37Rv) (MIC: 2 μg/ml).
价 格:¥电议型 号:T63755产 地:中国大陆