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T14296Antitumor agent-3Antitumor agent-3
Antitumor agent-3 is a potent compound. It comprises a new imidazopyridine having excellent antitumor activity as an active ingredient.
价 格:¥电议型 号:T14296产 地:美洲
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T83022Antiproliferative agent-33;化合物 Antiproliferative agent-33Antiproliferative agent-33
Antiproliferative Agent-33 (Compound 2g) serves as an anti-proliferative, antifungal, and antibacterial agent, effectively inhibiting the proliferation of MDA-MB-231 cells (IC50: 16.38 μM), impairing the growth of gram-negative bacteria, and restraining S. faecalis with an MIC of 8 μg/mL [1].
价 格:¥电议型 号:T83022产 地:中国大陆
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T83021Antiproliferative agent-36;抗增殖剂36Antiproliferative agent-36
Antiproliferative agent-36 is a broad-spectrum anticancer benzothiazolylhydrazone-derived compound that inhibits cell proliferation.
价 格:¥电议型 号:T83021产 地:中国大陆
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T83020Antiproliferative agent-37;化合物 Antiproliferative agent-37Antiproliferative agent-37
Antiproliferative agent-37 (compound 10J) inhibits cell proliferation by arresting cells at the G2/M phase of the cell cycle [1].
价 格:¥电议型 号:T83020产 地:中国大陆
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T83019Antiproliferative agent-38;化合物 Antiproliferative agent-38Antiproliferative agent-38
Antiproliferative Agent-38 (COM 18), a tetracyclic compound, features a reactive ring nitrogen (likely the quinoline moiety) that resists N-alkylation. Despite its classification, it neither exhibits anti-malarial properties nor inhibits cancer cell proliferation [1].
价 格:¥电议型 号:T83019产 地:中国大陆
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T83018Antiproliferative agent-39;化合物 Antiproliferative agent-39Antiproliferative agent-39
Antiproliferative Agent-39 (Compound 12) effectively inhibits the proliferation of various cancer cell lines, including A549, SNU-638, Col2, HT1080, and MCF-7, with respective IC50 values of 11, 25, 14, 11, and 6.3 μM [1].
价 格:¥电议型 号:T83018产 地:中国大陆
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T83005Antitumor agent-31;化合物 Antitumor agent-31Antitumor agent-31
Antitumor Agent-31 comprises nanosized chelates tethered to a bisazo dye, functioning as both an antioxidant and antitumor agent [1].
价 格:¥电议型 号:T83005产 地:中国大陆
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T83004Antitumor agent-39;化合物 Antitumor agent-39Antitumor agent-39
Antitumor Agent-39 is a peptide-based compound with anticancer properties[1].
价 格:¥电议型 号:T83004产 地:中国大陆
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T79410anti-TNBC agent-3;化合物 anti-TNBC agent-3anti-TNBC agent-3
Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties. It effectively inhibits tumor growth and metastasis in xenograft models of triple-negative breast cancer (TNBC) [1].
价 格:¥电议型 号:T79410产 地:中国大陆
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T79379Antitubercular agent-39;化合物 Antitubercular agent-39Antitubercular agent-39
Antitubercular agent-39 (Compound P1) is a potent agent effective against both drug-resistant strains and drug-susceptible clinical isolates of tuberculosis, exhibiting inhibition of the Mtb strain H37Rv with a minimum inhibitory concentration (MIC) of less than 1 μM [1].
价 格:¥电议型 号:T79379产 地:中国大陆
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T79368Antiproliferative agent-34;化合物 Antiproliferative agent-34Antiproliferative agent-34
Antiproliferative Agent-34 (Compound A14), a multitarget kinase inhibitor, demonstrates IC50 values of 177 nM for EGFR L858R/T790M and 1567 nM for EGFR WT. Additionally, it inhibits JAK2, ROS1, FLT3, FLT4, and PDGFRα with respective IC50s of 30.93 nM, 106.90 nM, 108.00 nM, 226.60 nM, and 42.53 nM. In normoxic conditions, it suppresses the proliferation of H1975 and HCC827 cells with IC50 values below 40 nM, while under hypoxic conditions, its potency increases 4-6 fold, yielding IC50 values less
价 格:¥电议型 号:T79368产 地:中国大陆
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T79332Antiproliferative agent-32;化合物 Antiproliferative agent-32Antiproliferative agent-32
Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells, induces apoptosis, and inflicts mitochondrial damage, rendering it a potential subject for hepatocellular carcinoma research [1].
价 格:¥电议型 号:T79332产 地:中国大陆
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T79322Antiproliferative agent-30;化合物 Antiproliferative agent-30Antiproliferative agent-30
Antiproliferative agent-30 (Compound 8g) demonstrates broad-spectrum antiproliferative activity, with IC50 values of 0.054 nM, 0.008 nM, and 0.144 nM against HCT-116, K562, and MV-4-11 cancer cell lines, respectively. It inhibits tubulin assembly as well as FLT3 and Abl1 kinases and exhibits vascular-disrupting capabilities. Additionally, it exerts an anticancer effect against acute myeloid leukemia (AML) with FLT3-ITD-TKD mutations [1].
价 格:¥电议型 号:T79322产 地:中国大陆
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T79288Antitubercular agent-38;化合物 Antitubercular agent-38Antitubercular agent-38
Antitubercular Agent-38, a derivative of Benzothiazinones (BTZs), demonstrates potent antituberculosis activity while maintaining low cardiac toxicity and minimal cell cytotoxicity [1]. This orally active compound is a promising therapeutic in the treatment of tuberculosis.
价 格:¥电议型 号:T79288产 地:中国大陆
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T78918Antitubercular agent-37;化合物 Antitubercular agent-37Antitubercular agent-37
Antitubercular Agent-37 exhibits antimycobacterial properties and functions as an antibacterial agent with an MIC (minimum inhibitory concentration) value of 0.16 μg/mL, making it suitable for tuberculosis research [1].
价 格:¥电议型 号:T78918产 地:中国大陆
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T75008Antitubercular agent-36;化合物 Antitubercular agent-36Antitubercular agent-36
Antitubercular agent-36 (compound 53) is an effective inhibitor of Mycobacterium tuberculosis H37Rv, displaying a minimum inhibitory concentration (MIC90) of 1.25 μg/mL and is utilized in tuberculosis research [1].
价 格:¥电议型 号:T75008产 地:中国大陆
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T75007Antitubercular agent-35;化合物 Antitubercular agent-35Antitubercular agent-35
Antitubercular Agent-35 (compound 42l) is an antitubercular agent effective against Mtb H37Rv and M. Marinum, exhibiting MIC 90 values of 1.25 and 2 μg/mL, respectively. It demonstrates resistance to metabolic degradation by human liver microsomes, rendering it a potential candidate for tuberculosis research [1].
价 格:¥电议型 号:T75007产 地:中国大陆
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T74393Antitumor agent-36;化合物 Antitumor agent-36Antitumor agent-36
Antitumor agent-36 exhibits strong anti-proliferative and anti-metastasis capabilities, causing significant DNA damage that results in elevated levels of γ-H2AX and p53. It promotes tumor cell apoptosis via the mitochondrial apoptotic pathway involving Bcl-2/Bax/caspase3 and enhances immune response by inhibiting PD-L1 expression, thereby increasing CD3+ and CD8+ T cell infiltration in tumor tissues [1].
价 格:¥电议型 号:T74393产 地:中国大陆
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T64022Antitumor agent-37;化合物 Antitumor agent-37Antitumor agent-37
Antitumor agent-37 exhibits potent anti-proliferative and anti-metastatic effects. antitumor agent-37 induces severe DNA damage, leading to high expression of γ-H2AX and p53. antitumor agent-37 induces apoptosis by exploiting the mitochondrial apoptosis pathway Bcl-2/Bax/caspase3. Antitumor agent-37 inhibits PD-L1 expression, increases CD3+ and CD8+ T-infiltrating cells in tumour tissue and significantly improves the immune response.
价 格:¥电议型 号:T64022产 地:中国大陆
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T63869Anti-Trypanosoma cruzi agent-3;化合物 Anti-Trypanosoma cruzi agent-3Anti-Trypanosoma cruzi agent-3
Anti-Trypanosoma cruzi agent-3 is an antiprotozoal agent.
价 格:¥电议型 号:T63869产 地:中国大陆