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T9975GPR183GPR183 antagonist-1,SAE-14,inhibit,SAE 14,SAE14,HL-60,GPR183,Inhibitor,GPR183 antagonist SAE-1
GPR183 is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholesterol (7α,25-OHC). GPR183 can be used in research on inflammatory bowel disease (IBD).
价 格：￥电议型 号：T9975产 地：中国大陆
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T11230ERRα antagonist-1
ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
价 格：￥电议型 号：T11230产 地：中国大陆
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T8649TMBIM6 antagonist-1TMBIM-6 antagonist-1,TMBIM6 antagonist 1,HT1080,SKBR3,TMBIM6 antagonist1,MCF7,Mam
BIA is a bax inhibitor
价 格：￥电议型 号：T8649产 地：中国大陆
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T11077Dopamine D2 receptor antagonist-1Dopamine D-2 receptor antagonist-1,Dopamine D2 receptor antagonist
Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of dopamine D2 receptor (D2R), with sub-mM affinity.
价 格：￥电议型 号：T11077产 地：中国大陆
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T9244σ1 Receptor antagonist-1anti-nociceptive,Sigma Receptor,cycle,σ1 Receptor antagonist1,σ1 Receptor an
σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.
价 格：￥电议型 号：T9244产 地：中国大陆
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T10031EP1-antagonist-1
EP1-antagonist-1 is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
价 格：￥电议型 号：T10031产 地：中国大陆
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T39078CXCR7 antagonist-1CXCR7 antagonist1,CXCR-7 antagonist-1,CXCR7 antagonist 1
CXCR7 antagonist-1 is a specific antagonist of the binding of the SDF-1 chemokine or I-TAC to the chemokine receptor CXCR7. CXCR7 antagonist-1 prevents tumor cell proliferation and tumor formation and can be used in studies about inflammatory diseases.
价 格：￥电议型 号：T39078产 地：中国大陆
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T11230ERRα antagonist-1ERRα antagonist-1
ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.ERRα antagonist-1 ?is a selective and high affinity estrogen-related rec
价 格：￥电议型 号：T11230产 地：美洲
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T8649TMBIM6 antagonist-1；1-（2-氨基苯基）-3-（3-硝基苯基）-2-丙烯-1-酮BAX-inhibitor-1|||BIA；BAX-inhibitor-1|||1-（2-氨基苯基）
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor
价 格：￥电议型 号：T8649产 地：中国大陆
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T81801mGluR5 antagonist-1；化合物 mGluR5 antagonist-1mGluR5 antagonist-1
mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].
价 格：￥电议型 号：T81801产 地：中国大陆
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T79793CRF1 receptor antagonist-1；化合物 CRF1 receptor antagonist-1CRF1 receptor antagonist-1
CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].
价 格：￥电议型 号：T79793产 地：中国大陆
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T79418BLT2 antagonist-1；化合物 BLT2 antagonist-1BLT2 antagonist-1
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not affecting CHO-BLT1 cell chemotaxis. It blocks the interaction between LTB4 and the BLT2 receptor with a K_i of 132 nM and may serve as a research tool for inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease [1].
价 格：￥电议型 号：T79418产 地：中国大陆
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T79071HPK1 antagonist-1；化合物 HPK1 antagonist-1HPK1 antagonist-1
HPK1 antagonist-1 (I-792) is an inhibitor targeting HPK1, with potential applications in cancer and immune disease research [1].
价 格：￥电议型 号：T79071产 地：中国大陆
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T79023CaSR antagonist-1；化合物 CaSR antagonist-1CaSR antagonist-1
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation of diseases related to dysregulated bone or mineral homeostasis, including osteoporosis [1].
价 格：￥电议型 号：T79023产 地：中国大陆
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T74854GluN2B-NMDAR antagonist-1；化合物 GluN2B-NMDAR antagonist-1GluN2B-NMDAR antagonist-1
GluN2B-NMDAR Antagonist-1, an orally active compound, functions as a GluN2B-NMDAR antagonist with neuroprotective properties. It is applicable in the research of ischemic injury [1].
价 格：￥电议型 号：T74854产 地：中国大陆
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T74606A2A/A3u00A0AR antagonist-1；化合物 A2A/A3u00A0AR antagonist-1A2A/A3u00A0AR antagonist-1
Compound 23, designated as A2A/A3 AR antagonist-1, is a dual fluorescent ligand targeting A2A and A3 adenosine receptors (AR), exhibiting dissociation constants (Ki) of 90 nM for hA2A AR and 31.8 nM for hA3 AR, respectively [1].
价 格：￥电议型 号：T74606产 地：中国大陆
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T72626A2AR-antagonist-1；化合物 A2AR-antagonist-1A2AR-antagonist-1
A2AR-antagonist-1 (compound 38), an orally active adenosine A2A receptor antagonist with an IC50 value of 29 nM, demonstrates anti-tumor properties and stability in mouse liver microsomes (t1/2 = 86.1 min). Additionally, it activates T cells by inhibiting immunosuppressive molecules (LAG-3 and TIM-3) and promoting expression of effector molecules (GZMB, IFNG, and IL-2) [1].
价 格：￥电议型 号：T72626产 地：中国大陆
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T72473NOD1/2 antagonist-1；化合物 NOD1/2 antagonist-1NOD1/2 antagonist-1
NOD1/2 Antagonist-1 is a potent dual inhibitor of nucleotide-binding oligomerization domain-like receptors 1 and 2 (NOD1/2), displaying inhibitory concentrations (IC50) of 1.13 μM for NOD1 and 0.77 μM for NOD2. It exhibits an acceptable half-life (T1/2) of 67.6 minutes. Additionally, NOD1/2 Antagonist-1 enhances the antitumor efficiency of Paclitaxel (PTX).
价 格：￥电议型 号：T72473产 地：中国大陆
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T64302XIAP/cIAP1 antagonist-1；化合物 XIAP/cIAP1 antagonist-1XIAP/cIAP1 antagonist-1
XIAP/cIAP1 antagonist-1 is a potent, orally active XIAP/cIAP1 antagonist that acts on XIAP (EC50: 5.1 nM) and cIAP1 (EC50: 0.32 nM). xIAP/cIAP1 antagonist-1 dose-dependently inhibits tumour growth in vivo.
价 格：￥电议型 号：T64302产 地：中国大陆
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T64024Dopamine D3 receptor antagonist-1；化合物 Dopamine D3 receptor antagonist-1Dopamine D3 receptor antagoni
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic potential for central nervous system disorders.
价 格：￥电议型 号：T64024产 地：中国大陆
