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T8439Clobenpropit dihydrobromideApoptosis,inhibit,Clobenpropit dihydrobromide,histamine H3R,antagonist,in
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
价 格:¥电议型 号:T8439产 地:中国大陆
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T10889CRTh2 antagonist 2CRTh2 antagonist 2,CRTh-2 antagonist 2
CRTh2 antagonist 2 is a selective and potent CRTH2 antagonist, IC50≤10 nM. CRTh2 antagonist 2 can be used to study the direction of androgenic alopecia.
价 格:¥电议型 号:T10889产 地:中国大陆
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T9975GPR183GPR183 antagonist-1,SAE-14,inhibit,SAE 14,SAE14,HL-60,GPR183,Inhibitor,GPR183 antagonist SAE-1
GPR183 is a chemotactic receptor known for its role in the maturation of B cells, and the endogenous ligand is the oxysterol 7α,25-dihydroxycholesterol (7α,25-OHC). GPR183 can be used in research on inflammatory bowel disease (IBD).
价 格:¥电议型 号:T9975产 地:中国大陆
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T10269AHR antagonist 2AHR antagonist 2
AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.
价 格:¥电议型 号:T10269产 地:中国大陆
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T63812MrgprX2 antagonist-8
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.
价 格:¥电议型 号:T63812产 地:中国大陆
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T101625-HT3 antagonist 35 HT3 antagonist 3,5-HT-3 antagonist 3,5HT3 antagonist 3
5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).
价 格:¥电议型 号:T10162产 地:中国大陆
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T11230ERRα antagonist-1
ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
价 格:¥电议型 号:T11230产 地:中国大陆
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T8649TMBIM6 antagonist-1TMBIM-6 antagonist-1,TMBIM6 antagonist 1,HT1080,SKBR3,TMBIM6 antagonist1,MCF7,Mam
BIA is a bax inhibitor
价 格:¥电议型 号:T8649产 地:中国大陆
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T15387GLP-1R Antagonist 1GLP 1R Antagonist 1,GLP1R Antagonist 1
GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).
价 格:¥电议型 号:T15387产 地:中国大陆
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T60145CCR6 antagonist 1CCR6antagonist1
CCR6 antagonist 1 is a CCR6 antagonist. CCR6 antagonist 1 inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).
价 格:¥电议型 号:T60145产 地:中国大陆
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T38622Bcl-xL antagonist 2Bcl xL antagonist 2,BclxL antagonist 2
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
价 格:¥电议型 号:T38622产 地:中国大陆
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T61813AMPA receptor antagonist-3
AMPA receptor antagonist-3 is an AMPA receptor antagonist (patent US20070027143A1).
价 格:¥电议型 号:T61813产 地:中国大陆
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T62420P2Y2R/GPR17 antagonist 1
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist. P2Y2R/GPR17 antagonist 1 shows IC50 values of 3.17 ?M and 1.67 ?M against P2Y2R and GPR17, respectively. P2Y2R/GPR17 antagonist 1 shows excellent metabolic stability in human liver microsomes.
价 格:¥电议型 号:T62420产 地:中国大陆
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T11137(E)-GABAB receptor antagonist 1(E) GABAB receptor antagonist 1,(E)GABAB receptor antagonist 1
(E)-GABAB receptor antagonist 1 is a trans-GABAB receptor antagonist 1. (E)-GABAB receptor antagonist 1 decreases GABA-induced IP3 (inositol trisphosphate) production with IC50 of 37.9 μM. GABAB receptor antagonist 1 is a selective and negative allosteric modulator of GABAB (γ-Aminobutyric acid) receptors.
价 格:¥电议型 号:T11137产 地:中国大陆
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T12320ORL1 antagonist 1ORL-1 antagonist 1,ORL1 antagonist 1
ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 nM).
价 格:¥电议型 号:T12320产 地:中国大陆
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T11077Dopamine D2 receptor antagonist-1Dopamine D-2 receptor antagonist-1,Dopamine D2 receptor antagonist
Dopamine D2 receptor antagonist-1 is a negative allosteric modulator (NAM) of dopamine D2 receptor (D2R), with sub-mM affinity.
价 格:¥电议型 号:T11077产 地:中国大陆
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T9983CCR8 antagonist 1
CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.
价 格:¥电议型 号:T9983产 地:中国大陆
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T125975-HT2 antagonist 15HT2 antagonist 1,5 HT2 antagonist 1,5-HT-2 antagonist 1
5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.
价 格:¥电议型 号:T12597产 地:中国大陆
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T39762AHR antagonist 5 free baseAHR antagonist 5 free base
AHR antagonist 5 free base is an orally active antagonist of AHR with IC50s of ~35-150 nM in human and rodent cell lines.
价 格:¥电议型 号:T39762产 地:中国大陆