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T79699anti-TNBC agent-2;化合物 anti-TNBC agent-2anti-TNBC agent-2
Anti-TNBC agent-2 (3j), a purine derivative, acts as an anti-triple negative breast cancer (TNBC) therapeutic. It promotes apoptosis in MDA-MB-231 cells, while also inhibiting their migration and angiogenesis. Moreover, anti-TNBC agent-2 suppresses tumor growth and metastasis, and downregulates Ki67 and CD31 protein expression in TNBC xenograft models. It may be utilized for TNBC research [1].
价 格:¥电议型 号:T79699产 地:中国大陆
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T79410anti-TNBC agent-3;化合物 anti-TNBC agent-3anti-TNBC agent-3
Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties. It effectively inhibits tumor growth and metastasis in xenograft models of triple-negative breast cancer (TNBC) [1].
价 格:¥电议型 号:T79410产 地:中国大陆
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T39815anti-TNBC agent-1;anti-TNBC agent-1anti-TNBC agent-1
anti-TNBC agent-1 is a highly effective compound specifically designed to target and combat triple-negative breast cancer (TNBC). It demonstrates remarkable potency against various breast cancer cell types, with IC50 values spanning from 0.20 μM to 0.27 μM. The mechanism of action of anti-TNBC agent-1 involves inducing apoptosis in SUM-159 cells through the mitochondria pathway, as well as causing G1 phase arrest in these cells.
价 格:¥电议型 号:T39815产 地:中国大陆