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T74412dTAGV-1-NEG TFA；化合物 dTAGV-1-NEG TFAdTAGV-1-NEG TFA
dTAGV-1-NEG TFA, a diastereomer, serves as the heterobifunctional negative control for dTAGV-1. It acts specifically as an FKBP12 F36V-selective degrader [1].
价 格：￥电议型 号：T74412产 地：中国大陆
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T40251dTAGV-1 TFA；dTAGV-1 TFAdTAGV-1 TFA
dTAGV-1 TFA is a highly effective and specific compound that targets mutant FKBP12 F36V fusion proteins for degradation. It possesses potent activity in inducing the degradation of the FKBP12 F36V -Nluc protein in living organisms.
价 格：￥电议型 号：T40251产 地：中国大陆
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T36255dTAGV-1-NEGdTAGV-1-NEGdTAGV 1 NEG|||dTAGV1NEG
Negative control for dTAGV-1.
价 格：￥电议型 号：T36255产 地：中国大陆
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T36254dTAGV-1 hydrochloride；dTAGV-1 hydrochloridedTAGV-1 hydrochloride
Hydrochloride salt of dTAGV-1. Suitable for use in vivo. Following ip administration of 10 mg/kg in mice: T = 4.43 h; Cmax = 2123 ng mL-1; AUCinf = 18517 hr*ng mL-1 and CL = 9.05 mL min-1 kg-1 Negative control dTAGV-1-NEG also available. Important: It is recommended that DMSO stock solutions of this compound are made and used on the same day and are not subjected to freeze/thaw.
价 格：￥电议型 号：T36254产 地：中国大陆
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T36253dTAGV-1；dTAGV-1dTAGV-1
Degrader targeting mutant FKBP12F36V fusion proteins. Comprises a ligand selective for F36V single-point mutated FKBP12, a linker and a von Hippel-Lindau (VHL)-binding ligand. Induces potent and selective degradation of FKBP12F36V fusion proteins in vitro and in vivo. Selectively degrades FKBP12F36V-EWS/FLI fusion proteins and inhibits cell proliferation in FKBP12F36V-EWS/FLI-expressing Ewing sarcoma cells. Hydrochloride salt available; suitable for in vivo use. Negative control dTAGV-1-NEG al
价 格：￥电议型 号：T36253产 地：中国大陆
