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产品数:86101
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T9758dCeMM3?degradation,dCeMM 3,dCeMM3?,Inhibitor,inhibit,CDK,CDK12,Cyclin dependent kinase,glue degrader
dCeMM3 is a glue degrader. dCeMM3 prompts an interaction of CDK12-cyclin K with a CRL4B ligase complex, result in inducing ubiquitination and degradation of cyclin K.
价 格:¥电议型 号:T9758产 地:中国大陆
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T8710MSABanti-tumor,Wnt,inhibit,MSAB,degradation,β-catenin,Inhibitor,Beta catenin,cancer
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.
价 格:¥电议型 号:T8710产 地:中国大陆
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T8978DD1DD 1,P70S6K degradation,Bax activation,mitochondrial membrane depolarization,S6K,proteasome inhib
DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
价 格:¥电议型 号:T8978产 地:中国大陆
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T8858DTHIBdegradation,HSP27,Inhibitor,inhibit,HSP70,HSF1,HSP,DTHIB,HSP90,cancer,nuclear,anticancer,Heat s
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
价 格:¥电议型 号:T8858产 地:中国大陆
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T6763XevinapantSM 406,SM406,Xevinapant,AT-406,oral,inhibit,Debio 1143,ovarian,IAP,degradation,Smac,AT 406
AT406 (SM-406, ARRY-334543) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
价 格:¥电议型 号:T6763产 地:中国大陆
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T21572Erythromycin A enol etherInhibitor,inhibit,Acidic,Erythromycin A enol ether,degradation
Erythromycin A enol ether is a degradation product of Erythromycin A which is a macrolide antibiotic.
价 格:¥电议型 号:T21572产 地:中国大陆
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T75026PROTAC TYK2 degradation agent1;化合物 PROTAC TYK2 degradation agent1PROTAC TYK2 degradation agent1
PROTAC TYK2 Degradation Agent1 is a potent, subtype-selective degrader of TYK2, exhibiting degradation activity with a DC50 of 14 nM. It is utilized in autoimmune disease research [1].
价 格:¥电议型 号:T75026产 地:中国大陆
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T35788Orlistat Degradation Product (sodium salt);Orlistat Degradation Product (sodium salt)Orlistat Degrad
Orlistat degradation product is a degradation product of the digestive lipase inhibitor orlistat . It is formed via hydrolytic and thermal degradation as well as digestion by human carboxyl ester lipase.
价 格:¥电议型 号:T35788产 地:中国大陆