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T79258sEH inhibitor-16；化合物 sEH inhibitor-16sEH inhibitor-16
sEH Inhibitor-16, a potent soluble epoxide hydrolase (sEH) inhibitor, exhibits an IC50 of 2 nM. It diminishes inflammatory damage associated with cerulein-induced acute pancreatitis (AP) in mice, making it suitable for inflammation and immunology research [1].
价 格：￥电议型 号：T79258产 地：中国大陆
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T73830BRD4 Inhibitor-16；化合物 BRD4 Inhibitor-16BRD4 Inhibitor-16
BRD4 Inhibitor-16 (Compound 4) is a potent inhibitor of bromodomain 4 (BRD4), whose overexpression is closely correlated with various human cancers through the regulation of histone post-translational modifications. It serves as a valuable tool for explorative studies focused on BRD4 inhibition, facilitating an enhanced comprehension of BRD4 inhibitor release-related information [1].
价 格：￥电议型 号：T73830产 地：中国大陆
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T62752KRAS inhibitor-16；化合物 KRAS inhibitor-16KRAS inhibitor-16
KRAS inhibitor-16 (compound 3-11) is a potent inhibitor of KRAS G12C (IC50: 0.457 μM). KRAS inhibitor-16 exhibits p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 3.06, 11.1 μM respectively. KRAS inhibitor-16 has potential to be studied in pancreatic, colorectal and lung cancers.
价 格：￥电议型 号：T62752产 地：中国大陆
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T62129HIV-1 inhibitor-16；化合物 HIV-1 inhibitor-16HIV-1 inhibitor-16
HIV-1 inhibitor-16 (compound 7a) is a potent HIV-1 inhibitor with an EC50 of 1.3 nM against wild-type HIV-1. HIV-1 inhibitor-16 also showed some inhibitory activity against HIV-1 K103N, E138K, Y181C and L100I strains with EC50s of 5.4 nM, 9.2 nM, 22 nM and 35 nM, respectively. HIV-1 inhibitor-16 showed good solubility and hepatic microsomal stability and did not exhibit significant CYP enzyme inhibitory activity or acute toxicity.
价 格：￥电议型 号：T62129产 地：中国大陆
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T28286P2Y1-IN-16；化合物 T28286P2Y1 inhibitor-16|||P2Y1 inhibitor 16；P2Y1 inhibitor-16|||P2Y1 inhibitor 16
P2Y1-IN-16 is a novel antagonist of P2Y1.
价 格：￥电议型 号：T28286产 地：中国大陆
