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  • T8535GAK inhibitor 49NAK,selective,GAK inhibitor-49,GAK inhibitor49,GAK inhibitor 49,Inhibitor,inhibit,AT

    GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).

    价 格：￥电议型 号：T8535产 地：中国大陆

  • T10525SCD1 inhibitor-4

    SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.

    价 格：￥电议型 号：T10525产 地：中国大陆

  • T82734ChoKα inhibitor-4；化合物 ChoKα inhibitor-4ChoKα inhibitor-4

    ChoKα Inhibitor-4 is a bioisosteric agent that effectively inhibits human choline kinase α1 (HChoK α1) with an IC50 of 0.66 μM. It demonstrates both inhibitory and antiproliferative effects on cancer cells, induces apoptosis through the mitochondrial pathway, and diminishes the expression of anti-apoptotic proteins [1].

    价 格：￥电议型 号：T82734产 地：中国大陆

  • T72715JNK3 inhibitor-4；化合物 JNK3 inhibitor-4JNK3 inhibitor-4

    JNK3 Inhibitor-4, a potent 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile derivative, demonstrates a strong inhibitory effect on JNK3 with an IC 50 value of 1.0 nM. It exhibits exceptional selectivity against JNK3 when compared to other protein kinases, including isoforms JNK1 (IC 50 = 143.9 nM) and JNK2 (IC 50 = 298.2 nM). Additionally, JNK3 Inhibitor-4 benefits from neuroprotective properties and is predicted to permeate the blood-brain barrier effectively.

    价 格：￥电议型 号：T72715产 地：中国大陆

  • T72679GLS1 Inhibitor-4；化合物 GLS1 Inhibitor-4GLS1 Inhibitor-4

    GLS1 Inhibitor-4 (compound 41e) is a powerful GLS1 inhibitor, demonstrating an IC50 of 11.86 nM. It exhibits antiproliferative effects, substantial metabolic stability, and strong GLS1 binding affinity. Furthermore, it interrupts glutamine metabolism, induces ROS production, and triggers apoptosis, culminating in notable antitumor activity [1].

    价 格：￥电议型 号：T72679产 地：中国大陆

  • T72582HIV-1 inhibitor-48；化合物 HIV-1 inhibitor-48HIV-1 inhibitor-48

    HIV-1 inhibitor-48 is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity [1] .

    价 格：￥电议型 号：T72582产 地：中国大陆

  • T72563HIV-1 inhibitor-49；化合物 HIV-1 inhibitor-49HIV-1 inhibitor-49

    HIV-1 Inhibitor-49, a HEPT analog, is an orally active non-nucleoside reverse transcriptase inhibitor with potent activity against HIV-1, demonstrating an IC 50 of 30 nM. It features an excellent pharmacokinetic profile and has shown to be potentially safe without acute toxicity in mouse models.

    价 格：￥电议型 号：T72563产 地：中国大陆

  • T72258BRM/BRG1 ATP Inhibitor-4；化合物 BRM/BRG1 ATP Inhibitor-4BRM/BRG1 ATP Inhibitor-4

    BRM/BRG1 ATP Inhibitor-4, a potent inhibitor of BRG1/BRM, is utilized in the research of cancers and BAF complex-related disorders.

    价 格：￥电议型 号：T72258产 地：中国大陆

  • T67767HIF-1 inhibitor-4；化合物 HIF-1 inhibitor-4HIF-1 inhibitor-4；HIF-1 inhibitor-4

    HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.

    价 格：￥电议型 号：T67767产 地：中国大陆

  • T63770PI3K/mTOR Inhibitor-4；化合物 PI3K/mTOR Inhibitor-4PI3K/mTOR Inhibitor-4

    PI3K/mTOR Inhibitor-4 is an orally active pan-I PI3K/mTOR inhibitor. PI3K/mTOR Inhibitor-4 is an enzyme inhibitor that acts on PI3Kα (IC50: 0.63 nM), PI3Kγ (IC50: 22 nM), PI3Kδ (IC50: 9.2 nM) and mTOR (IC50: 13.85 nM). PI3K/mTOR Inhibitor-4 can be used to study cancer.

    价 格：￥电议型 号：T63770产 地：中国大陆

  • T63700sEH inhibitor-4；化合物 sEH inhibitor-4sEH inhibitor-4

    sEH inhibitor-4 (compound B15) has been identified as a potent soluble epoxide hydrolase (SEH) inhibitor with a remarkable inhibitory potency of 0.03 ± 0.01 nm. Intensive structural modification efforts led to the discovery of this compound for its ability to decrease inflammation and alleviate pain in the presence of SEH.

    价 格：￥电议型 号：T63700产 地：中国大陆

  • T63591HIV-1 inhibitor-45；化合物 HIV-1 inhibitor-45HIV-1 inhibitor-45

    HIV-1 inhibitor-45 is a potent inhibitor of HIV-1 RNase H (IC50: 0.067 μM) and has antiviral effects.

    价 格：￥电议型 号：T63591产 地：中国大陆

  • T63317ATM Inhibitor-4；化合物 ATM Inhibitor-4ATM Inhibitor-4

    ATM Inhibitor -4 is a selective and potent ATM inhibitor (IC50: 0.32 nM) that strongly inhibits the activity of the PI3K kinase family and exhibits good metabolic stability. ATM Inhibitor -4 completely inhibits mTOR at 1 μM.

    价 格：￥电议型 号：T63317产 地：中国大陆

  • T63018HIV-1 inhibitor-43；化合物 HIV-1 inhibitor-43HIV-1 inhibitor-43

    HIV-1 inhibitor-43 is a potent inhibitor of HIV-1, acting on HIV-1 Y188L (EC50: 21.3 nM), K103N-Y181C (EC50: 6.2 nM), K103N (EC50< 0.7 nM) and Y181C (EC50< 0.7 nM). HIV-1 inhibitor-43 reduces the expression of HIV-1 RNA and protein p24.

    价 格：￥电议型 号：T63018产 地：中国大陆

  • T62690HIV-1 inhibitor-46；化合物 HIV-1 inhibitor-46HIV-1 inhibitor-46

    HIV-1 inhibitor-46 (compound 13d) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (EC50: 1.425 μM). HIV-1 inhibitor-46 can be used in the study of AIDS.

    价 格：￥电议型 号：T62690产 地：中国大陆

  • T62452HIV-1 inhibitor-40；化合物 HIV-1 inhibitor-40HIV-1 inhibitor-40

    HIV-1 inhibitor-40 (Compound 4ab) is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) (EC50: 1.9 nM) with no significant acute toxicity in vivo. Orexin receptor antagonist is a highly sensitive inhibitor of CYP.

    价 格：￥电议型 号：T62452产 地：中国大陆

  • T62319HIV-1 inhibitor-44；化合物 HIV-1 inhibitor-44HIV-1 inhibitor-44

    HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).

    价 格：￥电议型 号：T62319产 地：中国大陆

  • T62287HIV-1 inhibitor-42；化合物 HIV-1 inhibitor-42HIV-1 inhibitor-42

    HIV-1 inhibitor-42 (compound 5b) is a potent inhibitor of HIV-1 (IC50: 0.06 μM). HIV-1 inhibitor-42 inhibits HIV-1 RT RNA-dependent DNA polymerase (IC50: 0.518 μM) and DNA-dependent DNA polymerase (IC50. 0.072 μM).

    价 格：￥电议型 号：T62287产 地：中国大陆

  • T61031HIV-1 inhibitor-41；化合物 HIV-1 inhibitor-41HIV-1 inhibitor-41

    HIV-1 inhibitor-41 (Compound B23) is an orally active inhibitor of non-nucleoside HIV-1 reverse transcriptase with EC 50 values of 50 nM and 20.8 nM against mutant E138K strain and HIV-1 WT, respectively. HIV-1 inhibitor-41 exhibits low hERG inhibition, no apparent CYP enzymatic inhibition as well as no acute toxicity [1].

    价 格：￥电议型 号：T61031产 地：中国大陆

  • T60342HIV-1 inhibitor-47；化合物 HIV-1 inhibitor-47HIV-1 inhibitor-47

    HIV-1 inhibitor-47 is a compound that effectively inhibits HIV-1 by preventing the vif-dependent degradation of human APOBEC3G. It has a notable inhibition effect, with an IC50 value of 14.33 μM. Additionally, HIV-1 inhibitor-47 is involved in the synthesis of derivatives of 1-(2-pyrimidinyl)piperazine, which have the potential to exhibit antianxiety, antidepressant, and antipsychotic effects [1] [2] [3].

    价 格：￥电议型 号：T60342产 地：中国大陆

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