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产品数：86101
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T6588Mitoxantroneleukaemia,NSC301739,PKC,MCF-7,NSC 301739,lymphocytes,Topoisomerase,Mitoxantrone,HL60 cel
Mitoxantrone is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone intercalates into and crosslinks DNA, thereby disrupting DNA and RNA replication. This agent also binds to topoisomerase II, resulting in DNA strand breaks and inhibition of DNA repair. Mitoxantrone is less cardiotoxic compared to doxorubicin.
价 格：￥电议型 号：T6588产 地：中国大陆
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TN1037GroenlandicineTopoisomerase,Groenlandicine,inhibit,Inhibitor
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage;Groenlandicine may be a promising anti-Alzheimer´s disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities.
价 格：￥电议型 号：TN1037产 地：中国大陆
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T6800CCF642calcium,Inhibitor,PDI,CCF642,apoptosis,isomerases,disulfide,myeloma,CCF-642,protein,multiple,r
CCF642 is a novel PDI-inhibiting compound with antimyeloma activity.
价 格：￥电议型 号：T6800产 地：中国大陆
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TQ0088Exatecan MesylateExatecan,Exatecan Mesylate,Topoisomerase,Inhibitor,inhibit
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).
价 格：￥电议型 号：TQ0088产 地：中国大陆
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T7309TAS-103 dihydrochlorideBMS247615,Topoisomerase,TAS-103,TAS103,inhibit,TAS 103 dihydrochloride,BMS-24
TAS-103 (dihydrochloride) is a novel anticancer agent targeting both topoisomerase (Topo) I and Topo II.
价 格：￥电议型 号：T7309产 地：中国大陆
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T7187Genz-644282Genz 644282,Inhibitor,inhibit,Genz-644282,Topoisomerase
Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.
价 格：￥电议型 号：T7187产 地：中国大陆
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T7804Garenoxacin mesylate hydrateGarenoxacin mesylate hydrate,DNA/RNA Synthesis,Topoisomerase,S. pneumoni
Garenoxacin mesylate hydrate with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.
价 格：￥电议型 号：T7804产 地：中国大陆
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TN4660NiranthinNiranthin,inhibit,anti-leishmanial agent,leishmaniasis,Topoisomerase,Parasite,drug-resistan
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. Niranthin also exhibits anti-hepatitis B virus, antiinflammatory and antiallodynic actions.
价 格：￥电议型 号：TN4660产 地：中国大陆
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T7551Belotecan hydrochlorideBelotecan,Topoisomerase,CKD 602,Inhibitor,Belotecan hydrochloride,CKD602,inhi
Belotecan hydrochloride is a synthetic water-soluble camptothecin derivative and topoisomerase I inhibitor with potential antitumor activity
价 格：￥电议型 号：T7551产 地：中国大陆
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T6628PirarubicinTopoisomerase,Bacterial,inhibit,Autophagy,Inhibitor,Antibiotic,Pirarubicin
Pirarubicin is an anthracycline antibiotic. It is also a DNA/RNA synthesis inhibitor that intercalates into DNA and interacts with topoisomerase II, utilized as an antineoplastic agent.
价 格：￥电议型 号：T6628产 地：中国大陆
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T6407β-LapachoneARQ 501,ARQ501,Topoisomerase,Inhibitor,NSC26326,β-Lapachone,Apoptosis,NSC 26326,Autophagy
Beta-Lapachone is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.
价 格：￥电议型 号：T6407产 地：中国大陆
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T6567LevofloxacinOrthopoxvirus,Levofloxacin,BK Viremia,Topoisomerase,inhibit,Inhibitor,Antibiotic,DNA gyr
Levofloxacin is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections.
价 格：￥电议型 号：T6567产 地：中国大陆
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T8333Aurintricarboxylic acidTopoisomerase,Apoptosis,receptor,P2XRs,Influenza Virus,glioblastoma,anti-infl
Aurintricarboxylic acid is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
价 格：￥电议型 号：T8333产 地：中国大陆
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T70481,4-Naphthoquinoneoxidase,monoamine,1,4-Naphthoquinone,inhibit,naphthoquinone,MAO,topoisomerase,Inhi
1, 4-Naphthoquinone was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase activity[1].
价 格：￥电议型 号：T7048产 地：中国大陆
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T83885DXR Inhibitor 11a sodium；化合物 DXR Inhibitor 11a sodium1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase
DXR inhibitor 11a, with an IC50 value of 0.11 ?M, effectively inhibits P. falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR). It also demonstrates significant activity against P. falciparum´s growth in isolated human erythrocytes, with an IC50 of 0.37 ?M.
价 格：￥电议型 号：T83885产 地：中国大陆
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T80968Topoisomerase I inhibitor 10；化合物 Topoisomerase I inhibitor 10Topoisomerase I inhibitor 10
Compound 13, a topoisomerase I inhibitor 10, selectively inhibits leishmanial topoisomerase IB and exhibits antileishmanial activity. Specifically, it demonstrates efficacy against L. donovani promastigotes with an IC50 value of 27.91 μM [1].
价 格：￥电议型 号：T80968产 地：中国大陆
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T80967Topoisomerase I inhibitor 9；化合物 Topoisomerase I inhibitor 9Topoisomerase I inhibitor 9
Topoisomerase I Inhibitor 9 (compound 3d), a specific inhibitor of leishmanial topoisomerase IB, exhibits antileishmanial activity, demonstrating an IC50 value of 34.81μM against L. donovani promastigotes [1].
价 格：￥电议型 号：T80967产 地：中国大陆
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T79928Phosphomannose isomerase；化合物 Phosphomannose isomerasePhosphomannose isomerase
Phosphomannose isomerase, the initial enzyme in GDP-Man biosynthesis, catalytically facilitates the interconversion of fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P), playing a crucial role in cell wall synthesis and protein glycosylation. It is also recognized as a significant antifungal target against threats from A. flavus [1].
价 格：￥电议型 号：T79928产 地：中国大陆
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T79539Topoisomerase II inhibitor 16；化合物 Topoisomerase II inhibitor 16Topoisomerase II inhibitor 16
Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the ability to penetrate the brain and stabilize double-stranded DNA-enzyme cleavage complexes. It shows promise for research into Chagas disease [1].
价 格：￥电议型 号：T79539产 地：中国大陆
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T79506Topoisomerase II inhibitor 15；化合物 Topoisomerase II inhibitor 15Topoisomerase II inhibitor 15
Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity for head and neck tumors [1].
价 格：￥电议型 号：T79506产 地：中国大陆
