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T12721Rho-Kinase-IN-1Rho Kinase IN 1,RhoKinaseIN1
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.
价 格：￥电议型 号：T12721产 地：中国大陆
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T9564IRE1α kinase-IN-1endoribonuclease,Inositol requiring enzyme 1,cells,IRE1,oligomerization,IRE-1α kina
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM. It displays 100-fold selectivity for IRE1α over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, and also inhibits IRE1α RNase activity (IC50=80 nM)
价 格：￥电议型 号：T9564产 地：中国大陆
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T5466Tyrosine kinase-IN-1
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）
价 格：￥电议型 号：T5466产 地：中国大陆
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T12721Rho-Kinase-IN-1Rho-Kinase-IN-1
Rho-Kinase-IN-1 is a inhibitor of Rho kinase (ROCK) with Ki values of 30.5 and 3.9 nM for ROCK1 and ROCK2, respectively
价 格：￥电议型 号：T12721产 地：美洲
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T5466Tyrosine kinase-IN-1Tyrosine kinase-IN-1
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ，respectively）
价 格：￥电议型 号：T5466产 地：美洲
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T8817TIE-2/VEGFR-2 kinase-IN-1；化合物 T8817TIE-2/VEGFR-2 kinase-IN-1
TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1].
价 格：￥电议型 号：T8817产 地：中国大陆
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T79807JAK kinase-IN-1；化合物 JAK kinase-IN-1JAK kinase-IN-1
JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32 nM, 27 nM, and 3473 nM, respectively [1].
价 格：￥电议型 号：T79807产 地：中国大陆
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T72605C-RAF kinase-IN-1；化合物 C-RAF kinase-IN-1C-RAF kinase-IN-1
C-RAF kinase-IN-1 is a potent inhibitor of C-RAF kinase with an IC 50 of 0.193 μM. C-RAF kinase-IN-1 is a quinoline derivative. C-RAF kinase-IN-1 has the potential for the research of cancer diseases [1] .
价 格：￥电议型 号：T72605产 地：中国大陆
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T72604Multi-kinase-IN-1；化合物 Multi-kinase-IN-1Multi-kinase-IN-1
Multi-kinase-IN-1, a powerful kinase inhibitor, exhibits antitumor properties by inducing cell apoptosis. It is under investigation for its potential application in treating colorectal cancer.
价 格：￥电议型 号：T72604产 地：中国大陆
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T72522Aurora kinase-IN-1；化合物 Aurora kinase-IN-1Aurora kinase-IN-1
Aurora kinase-IN-1, a potent aurora kinase inhibitor, modulates cell cycle progression and induces apoptosis by upregulating G1 cell cycle inhibitory proteins (including p21 and p27), elevating G1 progressive cyclin D1, and downregulating G1-to-S progressive cyclins, thereby arresting the cell cycle at the G1/S boundary. It stands as a promising lead compound for the development of chemotherapeutic agents.
价 格：￥电议型 号：T72522产 地：中国大陆
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T61374Pantothenate kinase-IN-1；化合物 Pantothenate kinase-IN-1Pantothenate kinase-IN-1
Pantothenate Kinase-IN-1 (Compound 1) functions as a modulator of Pantothenate Kinase (PANK), exhibiting an inhibition concentration (IC50) value of 0.51 μM against PANK3. It demonstrates notable ligand efficiency with a LipE value of 2.8 [1].
价 格：￥电议型 号：T61374产 地：中国大陆
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T60783Aurora/LIM kinase-IN-1；化合物 Aurora/LIM?kinase-IN-1Aurora/LIM kinase-IN-1
Aurora/LIM kinase-IN-1 (Compound F114) is a potent aurora and lim kinase dual inhibitor. Aurora/LIM kinase-IN-1 inhibits the proliferation and invasion of GBM that may be used in drug development efforts for GBM, furthermore other cancers. Aurora kinases and lim kinases are the kinases which involved in neoplastic cell division and cell motility, respectively [1].
价 格：￥电议型 号：T60783产 地：中国大陆
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T60693Glutamate-5-kinase-IN-1；化合物 Glutamate-5-kinase-IN-1Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 (compound 50) is a potent glutamate-5-kinase (G5K) inhibitor which acts by altering the ATP binding site architecture for enzyme recognition (MIC = 4.1 μM). Glutamate-5-kinase-IN-1 has the potential for anti-TB research [1].
价 格：￥电议型 号：T60693产 地：中国大陆
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T5466Tyrosine kinase-IN-1；化合物Tyrosine kinase-IN-1Tyrosine kinase-IN-1
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）
价 格：￥电议型 号：T5466产 地：中国大陆
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T12721Rho-Kinase-IN-1；化合物Rho-Kinase-IN-1Rho-Kinase-IN-1
Rho-Kinase-IN-1 is an inhibitor of ROCK with Kis of 30.5 nM and 3.9 nM for ROCK1 and ROCK2, respectively. Rho-Kinase-IN-1 can be used in studies about excessive cell proliferation, remodeling, edema and inflammation diseases.
价 格：￥电议型 号：T12721产 地：中国大陆
