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T79859TIE-2/VEGFR-2 kinase-IN-4；化合物 TIE-2/VEGFR-2 kinase-IN-4TIE-2/VEGFR-2 kinase-IN-4
TIE-2/VEGFR-2 kinase-IN-4, a benzimidazole derivative, serves as a potent inhibitor of the tyrosine kinase receptors TIE-2 and VEGFR-2, exhibiting inhibitory concentration (IC50) values of 5.2 nM and 5.1 nM, respectively. This compound is utilized in angiogenesis research [1].
价 格：￥电议型 号：T79859产 地：中国大陆
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T78792Multi-kinase-IN-4；化合物 Multi-kinase-IN-4Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.18, and 2.09 μM. It exhibits broad-spectrum anti-cancer properties in HepG2, MCF-7, MDA-231, and HeLa cell lines, with IC50 values ranging from 1.94 to 7.1 ?M, and demonstrates lower toxicity in WI-38 cells (IC50 = 40.85 ?M). Additionally, it induces apoptosis and causes S-phase cell cycle arrest in HepG2 cells, and holds potential for can
价 格：￥电议型 号：T78792产 地：中国大陆
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T63511IRE1α kinase-IN-4；化合物 IRE1α kinase-IN-4IRE1α kinase-IN-4
IRE1α kinase-IN-4 (compound 6) is a potent inhibitor of IRE1α, exhibiting a Ki value of 140 nM. It acts as an ATP-competitive ligand for IRE1α [1].
价 格：￥电议型 号：T63511产 地：中国大陆
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T61730Tyrosine kinase-IN-4；化合物 Tyrosine kinase-IN-4Tyrosine kinase-IN-4
Tyrosine kinase-IN-4 (EXAMPLE 107) is a protein tyrosine kinase inhibitor [1].
价 格：￥电议型 号：T61730产 地：中国大陆
