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T9999Benzamide, N-(3-imidazo[2,1-b]thiazol-6-ylphenyl)-2-methoxySirtuin modulator-2,cardiovascular diseas
Benzamide, N-(3-imidazo[2,1-b]thiazol-6-ylphenyl)-2-methoxy exhibits antidiabetic, anti-inflammatory and antitumor activities.
价 格:¥电议型 号:T9999产 地:中国大陆
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T67745CB2R/FAAH?modulator-2CB2R/FAAH?modulator2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67745产 地:中国大陆
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T37734AMPA receptor modulator-2
AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.
价 格:¥电议型 号:T37734产 地:中国大陆
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T79101β-Catenin modulator-2;化合物 β-Catenin modulator-2β-Catenin modulator-2
β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].
价 格:¥电议型 号:T79101产 地:中国大陆
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T74397nAChR modulator-2;化合物 nAChR modulator-2nAChR modulator-2
nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .
价 格:¥电议型 号:T74397产 地:中国大陆
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T67745CB2R/FAAHu00A0modulator-2;化合物CB2R/FAAHu00A0modulator-2CB2R/FAAHu00A0modulator-2
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.
价 格:¥电议型 号:T67745产 地:中国大陆
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T62885GABAA receptor modulator-2;化合物 GABAA?receptor?modulator-2GABAA receptor modulator-2
GABAA receptor modulator-2 (Compound 20) is a selective, orally active α5-GABAAR negative conformation modulator (Ki: 4.1 nM). gABAA receptor modulator-2 exhibits high metabolic stability and a good central nervous system safety profile.
价 格:¥电议型 号:T62885产 地:中国大陆
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T62352CXCR4 modulator-2;化合物 CXCR4 modulator-2CXCR4 modulator-2
CXCR4 modulator-2 (compound Z7R) is a potent modulator of CXCR4 (IC50: 1.25 nM). CXCR4 modulator-2 exhibits good stability in mouse serum (t1/2= 77.1 min) and has anti-inflammatory effects in a mouse oedema model.
价 格:¥电议型 号:T62352产 地:中国大陆
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T61183MRGPRX4 modulator-2;化合物 MRGPRX4 modulator-2MRGPRX4 modulator-2
MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune diseases such as psoriasis, multiple sclerosis, Steven Johnson´s Syndrome, and various chronic itch conditions is notable [1].
价 格:¥电议型 号:T61183产 地:中国大陆
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T60541PCSK9 modulator-2;化合物 PCSK9 modulator-2PCSK9 modulator-2
PCSK9 modulator-2 (Compound 1) is a potent PCSK9 modulator (EC 50 = 202 nM) that has the potential to be used in hyperlipidemia research. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a recently validated therapeutic target for lowering low-density lipoprotein cholesterol (LDL-C) [1].
价 格:¥电议型 号:T60541产 地:中国大陆
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T37734AMPA receptor modulator-2;化合物AMPA receptor modulator-2AMPA receptor modulator-2
AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.
价 格:¥电议型 号:T37734产 地:中国大陆