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T8412(S,R,S)-AHPCInhibitor,inhibit,(S,R,S)AHPC,E3 ligase-recruiting Moiety,Ligands for E3 Ligase,(S,R,S)-
MDK7526 is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC is potential useful for the targeted degradation of the androgen receptor.
价 格:¥电议型 号:T8412产 地:中国大陆
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T7763Thalidomide-4-OHE3 ligase-recruiting Moiety,inhibit,Inhibitor,Thalidomide4OH,Cereblon ligand2,Ligand
Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs
价 格:¥电议型 号:T7763产 地:中国大陆
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TQ0121VH-298E3 ligase-recruiting Moiety,VH-298,Inhibitor,VH298,Ligands for E3 Ligase,VH 298,inhibit
VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by PHD enzymes.
价 格:¥电议型 号:TQ0121产 地:中国大陆
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T9381Thalidomide 5-fluorideIRAK4 protein,E3 ligase-recruiting Moiety,protac,Ligand for E3 Ligase,Thalidom
Thalidomide 5-fluoride is a chemical compound.
价 格:¥电议型 号:T9381产 地:中国大陆
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T12557PROTAC BET-binding moiety 1PROTAC BET-binding moiety 1
PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors
价 格:¥电议型 号:T12557产 地:美洲
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T12558PROTAC BET-binding moiety 2PROTAC BET-binding moiety 2
PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor.
价 格:¥电议型 号:T12558产 地:美洲
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T74256PROTAC BRD9-binding moiety 5;化合物 PROTAC BRD9-binding moiety 5PROTAC BRD9-binding moiety 5
PROTAC BRD9-binding moiety 5, a selective binder of BRD9 with an IC50 value of 4.20 μM, is utilized in PROTAC synthesis and exhibits antiproliferative activity against cancer cells [1].
价 格:¥电议型 号:T74256产 地:中国大陆
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T5821BC-1215化合物BC-1215Ligands for E3 Ligase|||E3 ligase-recruiting Moiety|||F-box protein 3 (Fbxo3)|||Inh
BC-1215 is an inhibitor of F-box protein 3 (FBXO3, a ubiquitin E3 ligase component, IC50=0.9 μg/mL for IL-1β release).
价 格:¥电议型 号:T5821产 地:中国大陆
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T40016Thalidomide-NH-CH2-COOH;化合物T40016inhibit|||Ligands for E3 Ligase|||E3 ligase-recruiting Moiety|||Inh
Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
价 格:¥电议型 号:T40016产 地:中国大陆
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T19172A-1210477-piperazinyl;化合物 T19172PROTAC Mcl1-binding moiety 1;PROTAC Mcl1-binding moiety 1
A-1210477-piperazinyl is a compound that specifically targets and binds to the protein myeloid cell leukemia 1 (MCL1). This compound is utilized in PROTAC technology, which harnesses the ability to selectively degrade target proteins.
价 格:¥电议型 号:T19172产 地:中国大陆
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T18641SirReal1-O-propargyl;化合物 T18641PROTAC Sirt2-binding moiety 1;PROTAC Sirt2-binding moiety 1
SirReal1-O-propargyl, a moiety based on SirReal1, is a selective and highly potent inhibitor of Sirtuin 2 (Sirt2), demonstrating an IC50 of 2.4 μM. It operates by binding to the cereblon ligand through a linker, facilitating the formation of PROTAC for the degradation of Sirt2[1].
价 格:¥电议型 号:T18641产 地:中国大陆
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T18613MV-1-NH-Me;化合物 T18613PROTAC IAP binding moiety 2;PROTAC IAP binding moiety 2
MV-1-NH-Me, an MV-1-derived IAP ligand, connects to an ABL inhibitor through a linker, resulting in the formation of SNIPER[1].
价 格:¥电议型 号:T18613产 地:中国大陆
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T18612Bestatin-amido-Me;化合物 T18612PROTAC IAP binding moiety 1;PROTAC IAP binding moiety 1
Bestatin-amido-Me, a derivative of Bestatin, acts as an IAP ligand and interacts with ABL inhibitor through a linker to produce SNIPER[1].
价 格:¥电议型 号:T18612产 地:中国大陆
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T18611AP1867-2-(carboxymethoxy);化合物 T18611PROTAC FKBP12-binding moiety 2;PROTAC FKBP12-binding moiety 2
AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molecules[1].
价 格:¥电议型 号:T18611产 地:中国大陆
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T18601Desmethyl-QCA276;化合物 T18601PROTAC BRD4-binding moiety 4;PROTAC BRD4-binding moiety 4
Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].
价 格:¥电议型 号:T18601产 地:中国大陆
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T18599PROTAC BRD4-binding moiety 1;化合物 T18599PROTAC BRD4-binding moiety 1
PROTAC BRD4-binding moiety 1 is a BRD4 ligand that binds to the cereblon ligand through a linker, enabling the formation of a PROTAC complex. This complex efficiently degrades BRD4[1].
价 格:¥电议型 号:T18599产 地:中国大陆
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T18595Dasatinib carbaldehyde;化合物Dasatinib carbaldehydePROTAC ABL binding moiety 4|||BMS-354825 carbaldehyd
Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].
价 格:¥电议型 号:T18595产 地:中国大陆
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T18594HG-7-85-01-Decyclopropane;化合物 T18594PROTAC ABL binding moiety 3;PROTAC ABL binding moiety 3
Decyclopropane, also known as HG-7-85-01, is a chemical compound with ABL inhibitor properties. It binds to the IAP ligand through a linker, resulting in the formation of SNIPER [1].
价 格:¥电议型 号:T18594产 地:中国大陆
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T18593GNF5-amido-Me;化合物 T18593PROTAC ABL binding moiety 2;PROTAC ABL binding moiety 2
GNF5-amido-Me, the moiety based on GNF5 (ABL inhibitor),binds through a linker to the IAP ligand forming SNIPER[1].
价 格:¥电议型 号:T18593产 地:中国大陆
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T13915LPROTAC BRD9-binding moiety 1 hydrochloride;化合物 T13915LPROTAC BRD9-binding moiety 1 hydrochloride (20
PROTAC BRD9-binding moiety 1 hydrochloride binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.
价 格:¥电议型 号:T13915L产 地:中国大陆