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产品数：86101
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T8485THIQmutant,MC Receptor,inhibit,THIQ,melanocortin,affinity,activity,erectile,selective,eliciting,Mela
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).
价 格：￥电议型 号：T8485产 地：中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格：￥电议型 号：T9072产 地：中国大陆
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T9320YK-3-237YK3237,inhibit,Sirtuin,p53,breast,cancer,triple-negative,mtp53,Mutant,TNBC,Inhibitor,deacety
YK-3-237 reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53.
价 格：￥电议型 号：T9320产 地：中国大陆
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T9521CHR-6494 TFACHR-6494,inhibit,apoptosis,Haspin Kinase,NRAS mutant melanoma cells,CHR 6494,mitotic cat
CHR-6494 TFA is a potent haspin inhibitor, with an?IC50?of 2 nM. It inhibits histone H3T3 phosphorylation. CHR-6494 TFA induces the?apoptosis?of cancer cells, including melanoma and breast cancer. CHR-6494 TFA can be used in the research of cancer
价 格：￥电议型 号：T9521产 地：中国大陆
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T7414ARS-853ARS 853,ARS-853,KRAS,Apoptosis,cancer,mutant,state,inhibit,Inhibitor,inactive,Ras,selective,c
ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells
价 格：￥电议型 号：T7414产 地：中国大陆
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T9246JNJ-63576253TRC-253,mutant,JNJ 63576253,resistant,wild-type,JNJ63576253,TRC 253,prostate,inhibit,And
JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).
价 格：￥电议型 号：T9246产 地：中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格：￥电议型 号：T9303产 地：中国大陆
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T8369Adagrasibinhibit,GDP-bound,mutant,MIA PaCa-2,MRTX-849,Adagrasib,selective,Inhibitor,MRTX 849,inactiv
MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. It selectively modifies mutant cysteine 12 in GDP-bound KRASG12C, and inhibits KRAS-dependent signaling.
价 格：￥电议型 号：T8369产 地：中国大陆
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T60076Oritinibpharmacodynamics,non-small cell lung cancer,EGFR-T790M,EGFR TKI,SH1028,Irreversible,mutant-s
Oritinib is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can be used in studies about the treatment of non-small cell lung cancer.
价 格：￥电议型 号：T60076产 地：中国大陆
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T9304(S)-SunvozertinibHER1,Her2,(S)Sunvozertinib,mutant forms of ErbB,Epidermal growth factor receptor,(S
DZD9008 is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
价 格：￥电议型 号：T9304产 地：中国大陆
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T2705Mutant EGFR inhibitor
Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.
价 格：￥电议型 号：T2705产 地：中国大陆
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T16161Mutant IDH1 inhibitor
Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
价 格：￥电议型 号：T16161产 地：中国大陆
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T12128Mutant IDH1-IN-2
Mutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of 16.6 nM in Fluorescence biochemical assay, IC50 of ＜22 nM in LS-MS biochemical assay.
价 格：￥电议型 号：T12128产 地：中国大陆
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T16161Mutant IDH1 inhibitorMutant IDH1 inhibitor
Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
价 格：￥电议型 号：T16161产 地：美洲
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T2705Mutant EGFR inhibitorMutant EGFR inhibitor
Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.
价 格：￥电议型 号：T2705产 地：美洲
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T77805KRAS G12C mutant protein inhibitor A-1；化合物 KRAS G12C mutant protein inhibitor A-1KRAS G12C mutant pr
KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.
价 格：￥电议型 号：T77805产 地：中国大陆
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T64079Mutant p53 modulator-1；化合物 Mutant p53 modulator-1Mutant p53 modulator-1
Mutant p53 modulator-1 is a mutant p53 modulator. mutant p53 modulator-1 is able to hinder the progression of cancers containing p53 mutations.
价 格：￥电议型 号：T64079产 地：中国大陆
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T40272KRAS mutant protein inhibitor 1；KRAS mutant protein inhibitor 1KRAS mutant protein inhibitor 1
KRAS mutant protein inhibitor 1 is a KRAS mutant protein inhibitor for potential treatment in cancer.
价 格：￥电议型 号：T40272产 地：中国大陆
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T39716Mutant IDH1-IN-6Mutant IDH1-IN-6Mutant IDH1-IN-6
Mutant IDH1-IN-6 is an orally active compound that effectively inhibits mutant isocitrate dehydrogenase (IDH) enzymes. It demonstrates potency and selectivity, with IC50 values of 6.27, 3.71, 36.9, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutants, respectively. Notably, Mutant IDH1-IN-6 exhibits lower activity in inhibiting wild-type IDH enzymes.
价 格：￥电议型 号：T39716产 地：中国大陆
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T2705Mutant EGFR inhibitor；化合物Mutant EGFR inhibitorMutant EGFR inhibitor
Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.
价 格：￥电议型 号：T2705产 地：中国大陆
