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T60080TMPHneurol disorder,nAChR,Nicotinic acetylcholine receptors,neuronal nicotinic receptors,selective i
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.
价 格:¥电议型 号:T60080产 地:中国大陆
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T88684BP-TQS4BP TQS,allosteric agonist,transmembrane site,Inhibitor,α7 nAChR,inhibit,Nicotinic acetylchol
4BP-TQS is an allosteric agonist of α7 nAChRs.
价 格:¥电议型 号:T8868产 地:中国大陆
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T7853(+)-Sparteineinhibit,Inhibitor,(+) Sparteine,nAChR,(+)-Sparteine,(+)Sparteine,Nicotinic acetylcholin
Pachycarpine is a natural product extracted from scotch broom, is a sodium channel blocker and a class 1a antiarrhythmic agent
价 格:¥电议型 号:T7853产 地:中国大陆
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T9787suvn-911nicotinic,antidepressant,nAChR,acetylcholine,neuronal,Inhibitor,SUVN-911,suvn911,suvn 911,de
suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.
价 格:¥电议型 号:T9787产 地:中国大陆
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T6607Nitenpyraminhibit,nAChR,Inhibitor,Nicotinic acetylcholine receptors,Nitenpyram
Nitenpyram is a nicotinic acetylcholine receptor (AchR) agonist, used as veterinary medicine to treat parasites of livestock and pets.
价 格:¥电议型 号:T6607产 地:中国大陆
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T7124DinotefuranParasite,inhibit,Inhibitor,nAChR,Dinotefuran,Nicotinic acetylcholine receptors,MTI446,MTI
Dinotefuran is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves disruption of the insect´s nervous system by inhibiting nicotinic acetylcholine receptors.
价 格:¥电议型 号:T7124产 地:中国大陆
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T9542NS3861α3β4 nAChR,inhibit,NS 3861,Inhibitor,NS3861,Heteromeric,Patch Clamp,Nicotinic acetylcholine re
NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) and bind with high affinity to heteromeric α3β4 and α4β2 nAChRs. NS3861 displays the β-subunit preference and a complete lack of activation at α4-containing receptors. The maximal efficacy of NS3861 appeared solely dependent on the nature of the ligand-binding domain. Furthermore, a principal subunit serine to threonine substitution may explain the lack of NS3861 activation at α4-containing receptors.
价 格:¥电议型 号:T9542产 地:中国大陆
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T8552PSEM 89S TFAPSEM 89S TFA,GlyR,Ion,inhibit,nAChR,channels,L141F,PSAM,Q79G,PSEM 89S,Nicotinic acetylch
PSEM 89S TFA is a brain-penetrant and selective ion channels agonist, and is orthogonally selective for Q79G and L141F, respectively.
价 格:¥电议型 号:T8552产 地:中国大陆
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TN1643Ferulamideinhibit,Ferulamide,nAChR,Inhibitor,Ferulic,Nicotinic acetylcholine receptors,anticholinest
Ferulamide, a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.
价 格:¥电议型 号:TN1643产 地:中国大陆
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T7422CCMIInhibitor,AVL 3288,inhibit,UCI 4083,Nicotinic acetylcholine receptors,CCMI,nAChR,AVL3288,UCI4083
CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
价 格:¥电议型 号:T7422产 地:中国大陆
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T7884NS 1738NS 1738,Nicotinic acetylcholine receptors,NSC213859,inhibit,Inhibitor,nAChR,NS-1738,NSC-21385
NS 1738 is a positive allosteric modulator of the α7-containing neuronal nicotinic acetylcholine receptors (nAChRs)
价 格:¥电议型 号:T7884产 地:中国大陆
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T7193Enceniclineinhibit,nAChR,Encenicline,EVP 6124,Nicotinic acetylcholine receptors,EVP6124,Inhibitor
Encenicline is a selective α7 nicotinic acetylcholine receptor (nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer´s disease.
价 格:¥电议型 号:T7193产 地:中国大陆
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T8318BNC210GAD,generalised anxiety disorder,Inhibitor,BNC 210,inhibit,BNC-210,nAChR,IW2143,IW 2143,Nicoti
BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
价 格:¥电议型 号:T8318产 地:中国大陆
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TQ0117A-867744A-867744,Autophagy,Inhibitor,inhibit,nAChR,A 867744,Nicotinic acetylcholine receptors,A86774
A-867744 is an effective and selective type II positive allosteric modulator of the α7 nAChR (EC50: 1.0 μM).
价 格:¥电议型 号:TQ0117产 地:中国大陆
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T12165nAChR agonist 1DUN71755
nAChR agonist 1 is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
价 格:¥电议型 号:T12165产 地:中国大陆
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T74397nAChR modulator-2;化合物 nAChR modulator-2nAChR modulator-2
nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .
价 格:¥电议型 号:T74397产 地:中国大陆
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T74396nAChR modulator-1;化合物 nAChR modulator-1nAChR modulator-1
nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .
价 格:¥电议型 号:T74396产 地:中国大陆
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T62317α7 nAchR-JAK2-STAT3 agonist 1;化合物 α7 nAchR-JAK2-STAT3 agonist 1α7 nAchR-JAK2-STAT3 agonist 1
α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM). α7 nAchR-JAK2-STAT3 agonist 1 has been shown to have a positive effect on iNOS, IL-1β and IL-1β in murine macrophages RAW264.7. α7 nAchR-JAK2-STAT3 agonist 1 was effective in inhibiting the expression of iNOS, IL-1β and IL-6 in mouse macrophages. α7 nAchR-JAK2-STAT3 agonist 1 inhibited LPS-induced NO release, NF-κB activation and cytokine production. α7 nAchR-JAK
价 格:¥电议型 号:T62317产 地:中国大陆
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T61064nAChR antagonist 1;化合物 nAChR antagonist 1nAChR antagonist 1
nAChR antagonist 1 (compound B15) is a highly effective antagonist of α7 nAChR, demonstrating an IC50 value of 3.3 μM. Its versatility makes it an ideal candidate for investigating the pathogenesis of schizophrenia, Alzheimer´s disease, and inflammatory disorders [1].
价 格:¥电议型 号:T61064产 地:中国大陆
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T40177nAChR agonist 2;nAChR agonist 2nAChR agonist 2
Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM, indicating high affinity for this receptor subtype.
价 格:¥电议型 号:T40177产 地:中国大陆