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产品数:86101
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已选条件
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T7703PK11007PK11007,inhibit,MDM-2/p53,Reactive Oxygen Species,Inhibitor,PK 11007,PK-11007
PK11007 is an anti-p53 drug.
价 格:¥电议型 号:T7703产 地:中国大陆
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T7697BIX-01294PRMT1,recurrent,Autophagy,H3K9me3,Inhibitor,Cdkn1a,inhibit,p53,Gadd45a,MLKL,Histone Methylt
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
价 格:¥电议型 号:T7697产 地:中国大陆
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TQ0133Amifostine thiol dihydrochlorideWR1065,Amifostine thiol dihydrochloride,Inhibitor,MDM-2/p53,WR-1065,
WR-1065 dihydrochloride can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs.
价 格:¥电议型 号:TQ0133产 地:中国大陆
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T6879LLY-507protein,inhibit,methyltransferase,methylation,breast,cancer,SMYD2,LLY-507,p53,Inhibitor,Histo
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
价 格:¥电议型 号:T6879产 地:中国大陆
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TQ0127NavtemadlinNavtemadlin,MDM-2/p53,inhibit,Ubiquitin ligase,Ubiquitin activating enzyme,E3 ligating en
AMG 232 is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM). It binds to MDM2 with a Kd of 0.045 nM.
价 格:¥电议型 号:TQ0127产 地:中国大陆
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T9320YK-3-237YK3237,inhibit,Sirtuin,p53,breast,cancer,triple-negative,mtp53,Mutant,TNBC,Inhibitor,deacety
YK-3-237 reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53.
价 格:¥电议型 号:T9320产 地:中国大陆
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TP1427LReACp53 acetateReACp53 acetate
ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.
价 格:¥电议型 号:TP1427L产 地:中国大陆
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T6954PRIMA-1NSC 281668,PRIMA1,Autophagy,Apoptosis,PRIMA-1,inhibit,NSC281668,MDM-2/p53,Ferroptosis,Inhibit
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
价 格:¥电议型 号:T6954产 地:中国大陆
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TQ0231NVP-CGM097NVP-CGM097,Ubiquitin ligase,inhibit,MDM-2/p53,E3 ligating enzyme,NVP-CGM-097,CGM 097,Ubiqu
NVP-CGM097 is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).
价 格:¥电议型 号:TQ0231产 地:中国大陆
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T6610NSC-207895XI006,MDMX,p53,LPS,Inhibitor,XI 006,MDM2,inhibit,MDM-2/p53,NSC-207895,NSC207895
NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase.
价 格:¥电议型 号:T6610产 地:中国大陆
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T6614Nutlin-3bNutlin 3b,Inhibitor,MDM-2/p53,Ubiquitin activating enzyme,Ubiquitin conjugating enzyme,inhi
Nutlin-3b is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 μM), 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
价 格:¥电议型 号:T6614产 地:中国大陆
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T41068P53R3P53R3,P-53R3
P53R3 is a potent p53 reactivator and restores sequence-specific DNA binding of p53 hot spot mutants, including p53 R175H , p53 R248W and p53 R273H . P53R3 induces p53-dependent antiproliferative effects with much higher specificity than PRIMA-1. P53R3 enhances the recruitment of wild-type p53 and p53 M237I to several target gene promoters. P53R3 strongly enhances the mRNA, total protein and cell surface expression of the death receptor death receptor 5 (DR5) . P53R3 is used for cancer research.
价 格:¥电议型 号:T41068产 地:中国大陆
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T8774MS7972inhibit,Inhibitor,MDM-2/p53,MS-7972,MS7972,MS 7972
MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM
价 格:¥电议型 号:T8774产 地:中国大陆
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T9698UC2288Attenuator,786-O,Inhibitor,UC-2288,MDM-2/p53,inhibit,UC2288,ovarian,RCC,HK2,UC 2288,p21,sorafe
UC2288 is a relatively selective p21 attenuator which is synthesized based Sorafenib. UC2288 attenuates p21 protein levels with minimal effect on p21 protein stability.
价 格:¥电议型 号:T9698产 地:中国大陆
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T8554KCC-07KCC07,BAI1,p53,inhibit,ADGRB1,anticancer,Inhibitor,DNA Alkylator/Crosslinker,MBD2,KCC-07,anti-
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling.
价 格:¥电议型 号:T8554产 地:中国大陆
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T8657KYP-2047eNOS,inhibit,POP,Neurotensin,Angiopoietins,MDM-2/p53,KYP 2047,prolyl oligopeptidase,Glioblas
KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.
价 格:¥电议型 号:T8657产 地:中国大陆
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T7539O6-Benzylguaninepancreatic,DNA/RNA Synthesis,transcriptional,PARP1,p53,inhibit,cyclin,O-6-Benzylguan
O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
价 格:¥电议型 号:T7539产 地:中国大陆
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T6911NSC-87877 disodiumApoptosis,Neuroblastoma,inhibit,Inhibitor,NSC 87877 disodium,PPAR,p53,Phosphatase,
NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.
价 格:¥电议型 号:T6911产 地:中国大陆
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T36964BML-259BML-259,protein,p53,CDK,death,disease,neurotoxicity,cell,Inhibitor,inhibit,Cyclin dependent k
BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.
价 格:¥电议型 号:T36964产 地:中国大陆
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T6910NSC59984NSC-59984,inhibit,Inhibitor,NSC59984,MDM-2/p53,NSC 59984
NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.
价 格:¥电议型 号:T6910产 地:中国大陆