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产品数:86101
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TN1118Tormentic aciddiabetes,transporter,glucose,Tormentic acid,phosphorylation,RAW 264.7,inhibit,Inhibito
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,
价 格:¥电议型 号:TN1118产 地:中国大陆
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T8976PD-089828EGFR,ATP,nonselective,PD 089828,PDGFR,autophosphorylation,PD089828,HER1,Epidermal growth fa
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
价 格:¥电议型 号:T8976产 地:中国大陆
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TP1015NFAT Inhibitorinhibit,NFAT Inhibitor 1,dephosphorylation,cell-permeable,NFAT-Luc,NFAT Inhibitor-1,In
NFAT inhibitor is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.
价 格:¥电议型 号:TP1015产 地:中国大陆
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T8423ML417neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 4
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
价 格:¥电议型 号:T8423产 地:中国大陆
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T7779Nelfinavirproduction,Human immunodeficiency virus,protease,myeloma,inhibit,AG-1341,phosphorylation,c
Nelfinavir is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
价 格:¥电议型 号:T7779产 地:中国大陆
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T6878LJI308viability,Ribosomal S6 Kinase (RSK),LJI-308,stimulation,phosphorylation,LJI308,inhibit,mutatio
LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
价 格:¥电议型 号:T6878产 地:中国大陆
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T2085PQ401MCF-7,PQ401,IGF-1R,cells,breast,PQ-401,PQ 401,inhibit,caspase,Apoptosis,autophosphorylation,can
PQ401 suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
价 格:¥电议型 号:T2085产 地:中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格:¥电议型 号:T9303产 地:中国大陆
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T6712Tyrphostin AG 879tyrosine,EGFR,phosphorylation,Tyrphostin AG-879,antiproliferation,Tyrphostin AG879,
Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.
价 格:¥电议型 号:T6712产 地:中国大陆
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T8719SC99orally,ERK,c-Src,SC 99,ATP-binding,phosphorylation,platelet,AKT,Janus kinase,activation,anti-mye
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activities
价 格:¥电议型 号:T8719产 地:中国大陆
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T8496MAZ51EGFR,Apoptosis,growth,phosphorylation,Inhibitor,inhibit,PDGFRβ,MAZ51,MAZ 51,tumor,VEGF-D,indoli
MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.
价 格:¥电议型 号:T8496产 地:中国大陆
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T12871Talmapimodcytotoxicity,multiple,inhibit,tumor,SCIO 469,SCIO469,cells,Hsp27,Inhibitor,phosphorylation
Talmapimod is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 kinases, including other MAPKs.
价 格:¥电议型 号:T12871产 地:中国大陆
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T8574SPHINXphosphorylation,mice,Inhibitor,AMD,SRPK,Serine-arginine protein kinases,small molecule,SPHINX,
SPHINX is a new generation inhibitor of SPRK1
价 格:¥电议型 号:T8574产 地:中国大陆
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T6734WZ8040HER1,WZ 8040,mutated,WZ8040,Inhibitor,phosphorylation,EGFR,NSCLC,Epidermal growth factor recep
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).
价 格:¥电议型 号:T6734产 地:中国大陆
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T79174’-Hydroxychalcone4’Hydroxychalcone,inhibit,phosphorylation,hepatoprotective,chalcone,mitochondrial,
4´-Hydroxychalcone is a chalcone metabolite with hepatoprotective activity
价 格:¥电议型 号:T7917产 地:中国大陆
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T14980CLK-IN-T3CDC-like,Dual specificity tyrosine phosphorylation regulated kinase,inhibit,Dual specificit
CLK-IN-T3 is an inhibitor of CLK1, CLK2, and CLK3 with IC50s of 0.67, 15, and 110 nM. CLK-IN-T3 exhibits anti-cancer activity.
价 格:¥电议型 号:T14980产 地:中国大陆
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TN6739Angolinephosphorylation,proliferation,STAT3,anticancer,inhibit,Angoline,Inhibitor,STAT,IL-6
Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation.
价 格:¥电议型 号:TN6739产 地:中国大陆
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T76381H1-7 (histone H1 phosphorylation site), PKA Substrate;化合物 H1-7 (histone H1 phosphorylation site), PK
H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].
价 格:¥电议型 号:T76381产 地:中国大陆
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T62554PPARγ phosphorylation inhibitor 1;化合物 PPARγ phosphorylation inhibitor 1PPARγ phosphorylation inhibit
PPARγ phosphorylation inhibitor 1 (Compound 10) is a potent PPARγ binding agent (IC50: 24 nM) with antidiabetic effects. PPARγ phosphorylation inhibitor 1 exhibited inhibition of CDK5-mediated PPARγ Ser273 phosphorylation (IC50: 160 nM) and little PPARγ agonism.
价 格:¥电议型 号:T62554产 地:中国大陆
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T39185pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;pp60 (v-SRC) Autophosphorylation Site, Phospho
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors.
价 格:¥电议型 号:T39185产 地:中国大陆