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T8806FluzoparibSHR 3162,homologous recombination repair,Inhibitor,poly ADP ribose polymerase,Fluzoparib,i
fluzoparib is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.
价 格:¥电议型 号:T8806产 地:中国大陆
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T6S0139Neobavaisoflavoneflavonoid,corylifolia,Neobavaisoflavone,anti-oxidation,polymerase,Apoptosis,anti-ca
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p4, IL-12p7, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages.
价 格:¥电议型 号:T6S0139产 地:中国大陆
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T9891PARP1-IN-8?poly ADP ribose polymerase,phthalazinone,PARP,inhibit,HFF cells,Lung adenocarcinoma,Inhib
PARP1-IN-8 is an effective inhibito of PARP1 (IC50 = 97 nM).
价 格:¥电议型 号:T9891产 地:中国大陆
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T9593Senaparibinhibit,poly ADP ribose polymerase,IMP 4297,Inhibitor,breast,pancreatic,IMP-4297,Senaparib,
Senaparib is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.
价 格:¥电议型 号:T9593产 地:中国大陆
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T6446ClevudineOrthopoxvirus,half-life,nucleoside,DNA/RNA Synthesis,analog,Inhibitor,polymerase,Hepatitis
Clevudine is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DN
价 格:¥电议型 号:T6446产 地:中国大陆
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T7896BYK204165BYK-204165,poly ADP ribose polymerase,Inhibitor,PARP,antitumor,inhibit,BYK204165,BYK 204165
BYK204165 is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)
价 格:¥电议型 号:T7896产 地:中国大陆
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T8184Fucosterolpoly ADP ribose polymerase,Fucosterol,Inhibitor,inhibit,Endogenous Metabolite,PARP
Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis via modulation of PPARα and C/EBPα expression.
价 格:¥电议型 号:T8184产 地:中国大陆
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T8647BCH001PARN,dyskeratosis,telomerase,stem,BCH 001,polynucleotide,TERC,rPAPD5,ncRNA,BCH001,polymerases,
BCH001 is a specific small-molecule inhibitor of PAPD5.
价 格:¥电议型 号:T8647产 地:中国大陆
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T6578ME0328ME 0328,inhibit,poly ADP ribose polymerase,ME-0328,ME0328,PARP,Inhibitor
ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.
价 格:¥电议型 号:T6578产 地:中国大陆
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T7212Delavirdine mesylatepolymerase,BHAP-U 90152,U90152,U 90152,Inhibitor,Reverse Transcriptase,Delavirdi
Delavirdine (mesylate) is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
价 格:¥电议型 号:T7212产 地:中国大陆
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T6941PI-1840cell proliferation,Proteasome,Caspase,proteasome substrates,poly ADP ribose polymerase,inhibi
PI-1840( IC50 = 27 nM)is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).
价 格:¥电议型 号:T6941产 地:中国大陆
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T8150NudifloramidePARP,nicotinamide-adenine,poly ADP ribose polymerase,PARP-1,failure,chronic,Nudiflorami
1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
价 格:¥电议型 号:T8150产 地:中国大陆
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T9165AZD5305repair,AZD5305,Inhibitor,poly ADP ribose polymerase,DNA,AZD-5305,PARP,inhibit,pathway,synthet
AZD5305 is a potent, selective and oral active PARP inhibitor.
价 格:¥电议型 号:T9165产 地:中国大陆
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T9024OUL35ARTD10,PARP,inhibit,DNA,OUL 35,NSC 39047,apoptosis,NSC-39047,PARP10,poly ADP ribose polymerase,
OUL35 is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.
价 格:¥电议型 号:T9024产 地:中国大陆
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T6768AZ6102AZ 6102,PARP,AZ-6102,Inhibitor,poly ADP ribose polymerase,inhibit,AZ6102
AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes and shows IC50 of 5 nM for Wnt pathway inhibition in DLD-1 cells.
价 格:¥电议型 号:T6768产 地:中国大陆
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T6780Benzamideneuroprotective,dopamine,Benzenecarboxamide,Inhibitor,PARP,poly ADP ribose polymerase,Pheny
Benzamide, an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.
价 格:¥电议型 号:T6780产 地:中国大陆
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T8964G244-LMInhibitor,G244LM,G244-LM,inhibit,poly ADP ribose polymerase,PARP,G244 LM,G-244-LM
G244-LM is a potent and specific inhibitor of tankyrase 1/2. G244-LM inhibits Wnt signaling.
价 格:¥电议型 号:T8964产 地:中国大陆
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T6842G007-LKG007LK,Inhibitor,poly ADP ribose polymerase,G-007-LK,G007 LK,PARP,inhibit,G007-LK
G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.
价 格:¥电议型 号:T6842产 地:中国大陆
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T82536DNA polymerase-IN-4;化合物 DNA polymerase-IN-4DNA polymerase-IN-4
DNA polymerase-IN-4 (Compd 5c), a coumarin derivative, exhibits antiretroviral activity, achieving an IC50 of 134.22 μM [1].
价 格:¥电议型 号:T82536产 地:中国大陆
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T80644DNA polymerase-IN-1;DNA polymerase 抑制剂1DNA polymerase-IN-1
DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an IC50 of less than 250 μM. DNA polymerase-IN-1 was shown to inhibit Taq DNA polymerase by RT- DNA polymerase-IN-1 showed antiretroviral activity in vitro by RT-PCR assay and can be used to study oxidative damage and colorectal cancer.
价 格:¥电议型 号:T80644产 地:中国大陆