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T4074GSK-872translocation,GSK-872,neurological,HMGB1,Receptor-interacting protein kinases,brain,GSK 872,c
GSK872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
价 格:¥电议型 号:T4074产 地:中国大陆
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T8423ML417neuroprotection,dopaminergic,β-arrestin,ML417,ML-417,translocation,phosphorylation,neurons,ML 4
ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).
价 格:¥电议型 号:T8423产 地:中国大陆
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T16040Mepazinediffuse,B cell,inhibit,large,mucosa associated lymphoid tissue lymphoma translocation gene 1
Mepazine is a potent and selective inhibitor of MALT1. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM. Mepazine enhances apoptosis and affects the cell viability.
价 格:¥电议型 号:T16040产 地:中国大陆
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T8730BMS986260nuclear translocation,TGFβR1,BMS-986260,FOXP3 expression,MINK,Transforming growth factor be
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
价 格:¥电议型 号:T8730产 地:中国大陆
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T83727Tat-NTS Peptide TFA;化合物 Tat-NTS Peptide TFATat-Nuclear Translocation Signal Peptide;Tat-Nuclear Tran
Tat-NTS peptide, a cell-penetrating compound, comprises the HIV-1 Tat protein transduction domain fused with a 10-amino acid sequence (residues 228-237) from the repeat III domain of annexin A1, serving as a nuclear translocation signal (NTS). This peptide hinders the interaction between annexin A1 and importin β, obstructing annexin A1´s nuclear entry in primary mouse hippocampal neurons. Tat-NTS effectively prevents apoptosis triggered by glucose-oxygen deprivation and reperfusion in the
价 格:¥电议型 号:T83727产 地:中国大陆
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T81449PKC-ε translocation inhibitor peptide;化合物 PKC-ε translocation inhibitor peptidePKC-ε translocation i
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαR trafficking [1].
价 格:¥电议型 号:T81449产 地:中国大陆