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T81133Sofituzumab vedotin；化合物 Sofituzumab vedotinDMUC5754A；DMUC5754A
Sofituzumab vedotin (DMUC5754A) is an antibody-drug conjugate (ADC) comprising an anti-MUC16 antibody linked to monomethyl auristatin E (MMAE) via a protease-cleavable linker, utilized for cancer research [1].
价 格：￥电议型 号：T81133产 地：中国大陆
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T78065Enfortumab vedotin-ejfv；化合物 Enfortumab vedotin-ejfvEnfortumab vedotin-ejfv
Enfortumab vedotin-ejfv is an antibody-drug conjugate targeting Nectin-4, employed in the treatment of urothelial carcinoma [1].
价 格：￥电议型 号：T78065产 地：中国大陆
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T77881Tisotumab vedotin；化合物 Tisotumab vedotinTisotumab vedotin
Tisotumab vedotin is an antibody-drug conjugate (ADC) that specifically targets tissue factor (TF). This compound combines a fully human monoclonal antibody directed against TF (TF-011) with the cytotoxic agent Monomethyl Auristatin E (MMAE), exhibiting potent antitumor activity in the investigation of advanced or metastatic solid tumors [1].
价 格：￥电议型 号：T77881产 地：中国大陆
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T77838Telisotuzumab vedotin；化合物 Telisotuzumab vedotinABBV-399；ABBV-399
Telisotuzumab vedotin (ABBV-399), an antibody-drug conjugate (ADCs), targets c-Met and comprises the cytotoxic agent Monomethyl Auristatin E (MMAE), the Telisotuzumab antibody, and a cleavable mc-val-cit-PABC linker. This compound is utilized in cancer research [1].
价 格：￥电议型 号：T77838产 地：中国大陆
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T77823Polatuzumab vedotin；化合物 Polatuzumab vedotinPolatuzumab vedotin
Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows promise for research into Large B-cell lymphomas (LBCL) [1].
价 格：￥电议型 号：T77823产 地：中国大陆
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T77186Zilovertamab vedotin；化合物 Zilovertamab vedotinZilovertamab vedotin
Zilovertamab vedotin (VLS-101) is a novel antibody-drug conjugate consisting of the humanized monoclonal antibody zilovertamab linked to the anti-microtubule cytotoxin monomethyl auristatin E (MMAE). Upon binding to ROR1 on tumor cells, zilovertamab vedotin is rapidly internalized and directed to lysosomes where the conjugate undergoes cleavage, releasing MMAE. This process induces apoptosis in the targeted cells. Zilovertamab vedotin has potential applications in cancer research [1].
价 格：￥电议型 号：T77186产 地：中国大陆
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T76707Brentuximab vedotin；维布妥昔单抗SGN-35；SGN-35
Brentuximab vedotin (SGN-35) is an antibody-activated molecule coupling (ADC) targeting CD30 with antitumor activity for the study of lymphomas.
价 格：￥电议型 号：T76707产 地：中国大陆
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T74178Glembatumumab vedotin；维汀-格仑妥木单抗CR011-vcMMAE|||CR 011 ADC|||CDX-011；CR011-vcMMAE|||CR 011 ADC|||CDX-0
Glembatumumab vedotin (CDX-011) is an antibody-activated small molecule coupling, Glembatumumab vedotin has potent anticancer effects and can be used in the study of triple negative breast cancer (TNBC).
价 格：￥电议型 号：T74178产 地：中国大陆
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T6897Monomethyl auristatin E；一甲基澳瑞他汀EVedotin|||MMAE；一甲基澳瑞他汀E|||Vedotin|||MMAE
Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
价 格：￥电议型 号：T6897产 地：中国大陆
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T39595Disitamab vedotin；维迪西妥单抗RC 48|||RC-48|||RC48；RC 48|||RC-48|||RC48
Disitamab vedotin (RC-48) is an antibo-active molecular conjugate (ADC) containing a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) that binds to the cytotoxic agent MMAE via a degradable linker. Disitamab vedotin showed anti-tumor and anti-proliferation activities in gastric cancer cells with different HER-2 expression levels, and inhibited the expression of HER-2 protein in gastric cancer cells.
价 格：￥电议型 号：T39595产 地：中国大陆
