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T9246JNJ-63576253TRC-253,mutant,JNJ 63576253,resistant,wild-type,JNJ63576253,TRC 253,prostate,inhibit,And
JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).
价 格:¥电议型 号:T9246产 地:中国大陆
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T9303MRTX1133KRAS,Ras,MRTX 1133,G12D,cells,active,wild-type,phosphorylation,mutant,MRTX1133,inactive,ERK,
MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D. MRTX1133 exhibits an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 inhibits mutant KRAS-dependent signal transduction by preventing SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex. MRTX1133 selectively inhibits KRAS G12D mutant tumor cells with no effect on KRAS wild-type. MRTX1133 exhibits single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor mode
价 格:¥电议型 号:T9303产 地:中国大陆
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T95022-Tridecanonevolatile,tomato,inhibit,insecticide,wild,2 Tridecanone,f. glabratum,Lycopersicon,nonalk
2-Tridecanone is a nonalkaloid insecticide isolated from the wild tomato Lycopersicon hirsutum f. glabratum. 2-Tridecanone is a volatile organic compound.
价 格:¥电议型 号:T9502产 地:中国大陆
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T40379Bax BH3 peptide (55-74), wild type;Bax BH3 peptide (55-74), wild typeBax BH3 peptide (55-74), wild t
Bax BH3 peptide (55-74), wild type is a 20-amino acid peptide (Bax 1) known for its ability to induce apoptosis in various cell line models.
价 格:¥电议型 号:T40379产 地:中国大陆