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CAY10717CAY10717CAY10717|||CAY-10717
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品牌名称:$brandModel.Title(进口品牌)型号:T36193 原产地:中国大陆 发布时间:2024/9/7 7:24:09更新时间:
产品摘要:CAY10717 is a multi-targeted kinase inhibitor that exhibits greater than 40% inhibition of 34 of 104 kinases in an enzymatic assay at a concentration of 100 nM. It has activity at multiple oncogenic kinases, with IC50 values less than 50 nM against wild-type EGFR and ABL and mutant ABLG250E, ABLY253F, ABLE255K, and B-RafV600E. CAY10717 is highly cytotoxic against a cancer cell panel that includes chemotherapy-sensitive and -resistant cell lines (EC50s = 0.4-158 nM). It also inhibits the growth o
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