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T10623BSH-IN-1；化合物BSH-IN-1BSH-IN-1
BSH-IN-1 is a potent and covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM and 427 nM for B. longum BSH and B. theta BSH).
价 格：￥电议型 号：T10623产 地：中国大陆
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T10557BLM-IN-1；化合物 T10557BLM-IN-1
BLM-IN-1 is an effective Bloom syndrome protein (BLM) inhibitor (KD: 1.81 μM; IC50: 0.95 μM). It induces DNA damage response, apoptosis and proliferation arrest in cancer cells
价 格：￥电议型 号：T10557产 地：中国大陆
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T10512Prenyl-IN-1；Prenyl抑制剂1Prenyl-IN-1
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson´s model. Prenyl-IN-1 showed anti-oxidative stress in a Parkinson´s model.
价 格：￥电议型 号：T10512产 地：中国大陆
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T10509Xanthine oxidase-IN-1；黄嘌呤氧化酶IN14-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid；4-(3-Cyano-5
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.
价 格：￥电议型 号：T10509产 地：中国大陆
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T10503ACAT-IN-1 cis isomer；ACAT抑制剂1(顺式异构体)ACAT-IN-1 cis isomer
ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases.
价 格：￥电议型 号：T10503产 地：中国大陆
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T10488BCR-ABL-IN-1；化合物 T10488BCR-ABL-IN-1
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.
价 格：￥电议型 号：T10488产 地：中国大陆
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T10484BCL2-IN-1；化合物 T10484BCL2-IN-1
BCL2-IN-1 is a potent Bcl-2 inhibitor (Ki <0.01 nM).
价 格：￥电议型 号：T10484产 地：中国大陆
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T10450BACE1-IN-1；化合物 T10450BACE1-IN-1
BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).
价 格：￥电议型 号：T10450产 地：中国大陆
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T10443Aβ42-IN-1 free base；化合物 T10443Aβ42-IN-1 free base
Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091 μM, and significantly diminishes brain Aβ42 levels in mice. Given these properties, Aβ42-IN-1 free base represents a potential disease-modifying agent for Alzheimer’s disease [1].
价 格：￥电议型 号：T10443产 地：中国大陆
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T10303Aminoacyl tRNA synthetase-IN-1化合物 T10303Aminoacyl tRNA synthetase IN 1|||Aminoacyl tRNA synthetaseIN
Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS).
价 格：￥电议型 号：T10303产 地：中国大陆
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T10286ALK/ROS1-IN-1；化合物 T10286ALK/ROS1-IN-1
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
价 格：￥电议型 号：T10286产 地：中国大陆
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T10211Aβ42-IN-1；化合物 T10211Aβ42-IN-1
Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM). Aβ42-IN-1 potently reduced Aβ42 levels with an IC 50 value of 0.091 μM in cultured cells without inhibiting CYP3A4. Aβ42-IN-1 shows a sustained pharmacokinetic profile.
价 格：￥电议型 号：T10211产 地：中国大陆
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T10201PDE IV-IN-1；化合物PDE IV-IN-1PDE IV-IN-1
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.
价 格：￥电议型 号：T10201产 地：中国大陆
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T1016011β-HSD1-IN-1；化合物11β-HSD1-IN-111β-HSD1-IN-1
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
价 格：￥电议型 号：T10160产 地：中国大陆
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T10154MAO-B-IN-1；化合物 T10154MAO-B-IN-1
MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.
价 格：￥电议型 号：T10154产 地：中国大陆
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T101515-Lipoxygenase-In-1；化合物 T101515-Lipoxygenase-In-1
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.
价 格：￥电议型 号：T10151产 地：中国大陆
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T10098PGS-IN-1；化合物PGS-IN-1KME-4；KME-4
PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).
价 格：￥电议型 号：T10098产 地：中国大陆
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T10082DPP-IV-IN-1；化合物 T10082DPP-IV-IN-1
DPP-IV-IN-1 is an effective inhibitor of dipeptidyl peptidase IV (DPP-IV), a serine protease (IC50: 4.6 nM).
价 格：￥电议型 号：T10082产 地：中国大陆
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T10079MAO-IN-1；MAO抑制剂1MAO-IN-1
MAO-IN-1 is a potent monoamine oxidase B (MAO B) inhibitor (IC50: 20 nM) for the study of neurologically related diseases.
价 格：￥电议型 号：T10079产 地：中国大陆
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T10033COX-2-IN-1；化合物COX-2-IN-1COX-2-IN-1
COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).
价 格：￥电议型 号：T10033产 地：中国大陆
