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  • T37585Ensartinib；Ensartinib (X-396)Ensartinib

    Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively.

    价 格：￥电议型 号：T37585产 地：中国大陆

  • T37584Tryptoquivaline D；Tryptoquivaline DTryptoquivaline D

    Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 μM.1Tryptoquivaline D (1-100 μM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.2

    价 格：￥电议型 号：T37584产 地：中国大陆

  • T37583XTT (sodium salt hydrate)；XTT (sodium salt hydrate)XTT (sodium salt hydrate)

    XTT is a cell-impermeable, negatively charged tetrazolium dye that produces a water-soluble formazan when reduced at the cell surface by cellular-derived NADH and an electron mediator.1,2It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.3

    价 格：￥电议型 号：T37583产 地：中国大陆

  • T37582Ganglioside GM1 Mixture (ovine) (ammonium salt)；Ganglioside GM1 Mixture (ovine) (ammonium salt)Gangl

    Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i

    价 格：￥电议型 号：T37582产 地：中国大陆

  • T37581SCIO 469 hydrochloride；SCIO 469 hydrochlorideSCIO 469 hydrochloride

    Selective, ATP-competitive p38 inhibitor (IC50 = 9 nM for p38α in vitro). Displays approximately 10-fold selectivity for p38α over p38β and 2000-fold selectivity for p38α over 20 other kinases. Reduces p38α phosphorylation in multiple myeloma cells in vitro and in vivo; activity results in decreased tumor burden and angiogenesis in murine models of multiple myeloma. Also enhances bortezomib-induced cytotoxicity against multiple myeloma cells.

    价 格：￥电议型 号：T37581产 地：中国大陆

  • T37580Arachidonoyl thio-PC；Arachidonoyl thio-PCArachidonoyl thio-PC

    Arachidonoyl Thio-PC is a substrate for many phospholipase A2s (PLA2s) including sPLA2, cPLA2, and iPLA2. Cleavage of the sn-2 fatty acid by PLA2 results in generation of a free thiol which reacts with chromogenic reagents such as DTNB (Ellman´s reagent) and DTP to allow quantitation of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by excluding or inhibiting sPLA2 and iPLA2 activities in the assay.

    价 格：￥电议型 号：T37580产 地：中国大陆

  • T37582,6-Dimethoxybenzoic acid；2,6-二甲氧基苯甲酸2,6-Dimethoxybenzoic acid

    2, 6-Dimethoxybenzoic acid is an active biochemical.

    价 格：￥电议型 号：T3758产 地：中国大陆

  • T37558Necrostatin-5坏死抑制素5|Nec-5

    Necrostatin-5 (Nec-5) is a selective inhibitor of RIP1 kinase and a cell necrosis inhibitor that prevents the death of Fadd-deficient Jurkat cells treated with TNF-α with an EC50 value of 240 nM.

    价 格：￥电议型 号：T37558产 地：中国大陆

  • T37477L-858,051 (hydrochloride)；L-858,051 (hydrochloride)L-858,051 (hydrochloride)

    L-858,051 is a water-soluble analog of forskolin , a cell-permeant activator of adenylate cyclase. L-858,051 activates adenylate cyclase (EC50 = 3 μM), inhibits glucose transport, and blocks cytochalasin B binding in rat adipocyte membranes. L-858,051 is used to activate adenylate cyclase and initiate signaling through elevated cAMP synthesis in a variety of cell types in culture.

    价 格：￥电议型 号：T37477产 地：中国大陆

  • T37458C18 Phytoceramide (t18:0/18:0)；C18 Phytoceramide (t18:0/18:0)C18 Phytoceramide (t18:0/18:0)

    C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in S. cerevisiae, wheat grains, and the stratum corneum layer of mammalian epidermis. Cer(t18:0/18:0) is composed of a phytosphingosine backbone amine-linked to a C18 fatty acid chain. Cer(t18:0/18:0) has a role in regulation of apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain. It also inhibits expression of the allergic cytokines IL-4, TN

    价 格：￥电议型 号：T37458产 地：中国大陆

  • T37358Myristelaidic AcidMyristelaidic AcidMyristelaidic Acid

    Myristelaidic Acid is a natural product for research related to life sciences. The catalog number is T37358 and the CAS number is 50286-30-1.

    价 格：￥电议型 号：T37358产 地：中国大陆

  • T3725813-methyl Myristic Acid methyl ester；13-methyl Myristic Acid methyl ester13-methyl Myristic Acid met

    13-methyl Myristic acid methyl ester is a methylated bacterial fatty acid methyl ester. It has been used as a marker of bacteria in sewage sludges and of bacterial contaminants in pharmaceutical manufacturing by GC-MS.

    价 格：￥电议型 号：T37258产 地：中国大陆

  • T371588(S)-HETE；8(S)-HETE8(S)-HETE

    8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

    价 格：￥电议型 号：T37158产 地：中国大陆

  • T37089Iclepertin；化合物 IclepertinBI-425809；BI-425809

    Iclepertin (BI-425809) is an orally active and selective inhibitor of glycine transporter protein 1 (GlyT1).Iclepertin is used for the treatment of central nervous system disorders such as Alzheimer;s disease. Iclepertin is used for central nervous system disorders such as Alzheimer;s disease, schizophrenia and cognitive disorders.

    价 格：￥电议型 号：T37089产 地：中国大陆

  • T37058D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)；D-myo-Inositol-1,3,4,5-tetraphosphate (sodium sa

    D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell.

    价 格：￥电议型 号：T37058产 地：中国大陆

  • T37048LMMP-3 Inhibitor acetate；化合物MMP-3 Inhibitor acetateMMP-3 Inhibitor acetate(158841-76-0 Free base)；MMP

    MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.

    价 格：￥电议型 号：T37048L产 地：中国大陆

  • T36959BODIPY 558/568 C12；BODIPY 558/568 C12Red C12；Red C12

    BODIPY 558/568 C12 is a fatty acid-conjugated fluorescent probe for lipid droplets. [1] [2] It displays excitation/emission maxima of 558/568 nm, respectively, and has been used to monitor the localization and dynamics of lipid droplets in live cells.

    价 格：￥电议型 号：T36959产 地：中国大陆

  • T36958BODIPY 505/515；化合物 BODIPY 505/515BODIPY 505/515

    BODIPY 505/515 is a lipophilic fluorescent probe that localises to intracellular liposomes and has been used to label lipid droplets.BODIPY 505/515 has been used in electron microscopy, epifluorescence microscopy, confocal microscopy, and flow cytometry applications for various algal species.

    价 格：￥电议型 号：T36958产 地：中国大陆

  • T36924CYM 50358 hydrochloride；CYM 50358 hydrochlorideCYM 50358 hydrochloride

    CYM 50358 hydrochloride is a potent and selective S1PR4 antagonist with an IC50 of 25 nM. CYM 50358 hydrochloride can be used in the study of influenza infection.

    价 格：￥电议型 号：T36924产 地：中国大陆

  • T36858C12 Galactosylceramide (d18:1/12:0)；C12 Galactosylceramide (d18:1/12:0)C12 Galactosylceramide (d18:1

    C12 Galactosylceramide is a bioactive sphingolipid. It inhibits IL-4 production by 53.84% in EL4 T cells when used at a concentration of 10 μM. C12 Galactosylceramide reduces the growth of human papillomavirus type 16-associated tumors in mice and reduces tumor recurrence following surgical removal or chemotherapy. It also reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus.

    价 格：￥电议型 号：T36858产 地：中国大陆

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