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T39071Thailanstatin D;Thailanstatin DThailanstatin D
Thailanstatin D, an analogue of Thailanstatin A, inhibits AR-V7 gene splicing by disrupting the interaction between U2AF65 and SAP155, hindering their binding to the polypyrimidine tract situated between the branch point and the 3´ splice site. This compound displays potent tumor inhibitory properties in human castration-resistant prostate cancer (CRPC) xenografts, resulting in cellular apoptosis.
价 格:¥电议型 号:T39071产 地:中国大陆
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T38539Luseogliflozin hydrate鲁格列净水合物鲁格列净水合物|||TS 071 hydrate
Luseogliflozin (TS 071) hydrate, a second-generation sodium-glucose co-transporter 2 (SGLT2) inhibitor, exhibits selective potency and oral activity, with an IC50 of 2.26 nM. This compound is utilized in research for the treatment of type 2 diabetes mellitus (T2DM).
价 格:¥电议型 号:T38539产 地:中国大陆
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T38071HPF;HPFHPF
The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). [2] HPF is a cell-permeable aroma
价 格:¥电议型 号:T38071产 地:中国大陆
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T37685CAY10719;CAY10719CAY10719;CAY10719
CAY10719 is a selective inhibitor of the breast cancer resistance protein ABCG2 (IC50 = 0.23 μM) with little activity at ABCG1. It has been shown to reverse the ABCG2-mediated resistance toward SN 38 and to inhibit ATPase activity.
价 格:¥电议型 号:T37685产 地:中国大陆
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T37464CAY10711CAY10711CAY-10711|||CAY10711
CAY10711 is a substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria, including methicillin-resistant S. aureus (MRSA) and stationary-phase bacteria. It displays MIC99 values of 2.9, 11.5, 2.9, and 2.9 μM against S. aureus RN4220, P. aeruginosa PAO1, E. coli ANS1, and MRSA 10082B, respectively. CAY10711 reduces biofilm formation and promotes biofilm dispersal in P. aeruginosa. It is synergistic with kanamycin and has limited adverse ef
价 格:¥电议型 号:T37464产 地:中国大陆
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T37071Pyrimethanil;嘧霉胺Pyrimethanil
Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class. Pyrimethanil is a broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops. Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea.
价 格:¥电议型 号:T37071产 地:中国大陆
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T36501CYPMPO;CYPMPORR 071;RR 071
CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C),
价 格:¥电议型 号:T36501产 地:中国大陆
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T36193CAY10717CAY10717CAY10717|||CAY-10717
CAY10717 is a multi-targeted kinase inhibitor that exhibits greater than 40% inhibition of 34 of 104 kinases in an enzymatic assay at a concentration of 100 nM. It has activity at multiple oncogenic kinases, with IC50 values less than 50 nM against wild-type EGFR and ABL and mutant ABLG250E, ABLY253F, ABLE255K, and B-RafV600E. CAY10717 is highly cytotoxic against a cancer cell panel that includes chemotherapy-sensitive and -resistant cell lines (EC50s = 0.4-158 nM). It also inhibits the growth o
价 格:¥电议型 号:T36193产 地:中国大陆
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T3619VU0357017 hydrochloride;盐酸 VU 0357017ML071 hydrochloride|||CID-25010775|||VU 0357017 hydrochloride;M
VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.37 ± 0.15).
价 格:¥电议型 号:T3619产 地:中国大陆
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T36071Silodosin Glucuronide (sodium salt);Silodosin Glucuronide (sodium salt)Silodosin Glucuronide (sodium
Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.
价 格:¥电议型 号:T36071产 地:中国大陆
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T35071VPC32179;化合物 T35071VPC 32179|||VPC-32179;VPC 32179|||VPC-32179
VPC32179 is a bioactive chemical.
价 格:¥电议型 号:T35071产 地:中国大陆
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T34653SK1071;化合物 T34653SK1071
SK1071 is a novel migrastatin analogs, which demonstrated improved performance over migrastatin, with nanomolar IC50 values in chamber cell migration assays with tumor cells and human umbilical vein endothelial cells (HUVECs), and in wound healing assays.
价 格:¥电议型 号:T34653产 地:中国大陆
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T34071Piperphentonamine HCl;化合物 T34071PPTA;PPTA
Piperphentonamine HCL is a potential calcium sensitizer for the treatment of heart failure.
价 格:¥电议型 号:T34071产 地:中国大陆
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T33827Oseltamivir carboxylate HCl;化合物 T33827Oseltamivir carboxylate(HCI)|||GS4071 HC|||Oseltamivir carboxy
Oseltamivir carboxylate is an active metabolite of oseltamivir phosphate (Tamiflu).
价 格:¥电议型 号:T33827产 地:中国大陆
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T33636Neospiran;化合物 T33636NSC16071|||NSC 16071|||NSC-16071;NSC16071|||NSC 16071|||NSC-16071
Neospiran can be used in intracardial injections.
价 格:¥电议型 号:T33636产 地:中国大陆
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T33071Lysinoalanine;化合物 T33071LAL|||CCRIS-5632|||CCRIS 5632|||CCRIS5632;LAL|||CCRIS-5632|||CCRIS 5632|||CC
Lysinoalanine is an unusual amino acid, not a dipeptide, which exists in proteins of cooked foods. It is formed in food that is heated or treated with alkali.
价 格:¥电议型 号:T33071产 地:中国大陆
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T32453L 650719;化合物 T324536-HTS|||L650719|||L-650719;6-HTS|||L650719|||L-650719
L 650719 is a bioactive chemical.
价 格:¥电议型 号:T32453产 地:中国大陆
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T32071Hexopyrronium bromide;化合物 T32071Hexopyrronii bromidum;Hexopyrronii bromidum
Hexopyrronium bromide is a biochemical.
价 格:¥电议型 号:T32071产 地:中国大陆
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T32000GSK-1071306;化合物 T32000Pazopanib metabolite M27;Pazopanib metabolite M27
GSK-1071306 is a bio-active chemical.
价 格:¥电议型 号:T32000产 地:中国大陆
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T31932GJ071 oxalate;GJ071草酸盐GJ 071|||GJ-071|||GJ071;GJ 071|||GJ-071|||GJ071
GJ071 oxalate is a Nonsense suppressor. Nonsense suppressors (NonSups) induce “readthrough”, i.e., the selection of near cognate tRNAs at premature termination codons and insertion of the corresponding amino acid into nascent polypeptide.
价 格:¥电议型 号:T31932产 地:中国大陆