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T11495LGSK 4027GSK 4027
GSK 4027 is a PCAF/GCN5 bromodomain chemical probe. In a time-resolved fluorescence resonance energy transfer (TR-FRET) assay, it has a pIC50 of 7.4±0.11 for PCAF.
价 格:¥电议型 号:T11495L产 地:美洲
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T11496GSK598809GSK598809
GSK598809 is a selective and potent dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9.
价 格:¥电议型 号:T11496产 地:美洲
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T11497GSK656GSK656
GSK656 acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS),?is a potent antitubercular agent, with an IC50 of 0.2 μM.?
价 格:¥电议型 号:T11497产 地:美洲
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T11498GSK682753AGSK682753A
GSK682753A is a selective and highly potent inverse agonist of the epstein-barr virus-induced receptor 2 (EBI2) with an IC50 of 53.6 nM.?
价 格:¥电议型 号:T11498产 地:美洲
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T13089TAS-114TAS-114
TAS-114 is a dual inhibitor of dUTPase/dihydropyrimidine dehydrogenase (DPD), and can improving the therapeutic efficacy of fluoropyrimidine.
价 格:¥电议型 号:T13089产 地:美洲
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T13114CCR2 antagonist 4CCR2 antagonist 4,Teijin compound 1,
CCR2 antagonist 4 is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM).
价 格:¥电议型 号:T13114产 地:美洲
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T13325VU 0365114VU 0365114
VU 0365114 is an positive allosteric modulator of mAChR M5(EC50 of 2.7 μM).
价 格:¥电议型 号:T13325产 地:美洲
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T13583BIZ 114BIZ 114
BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.
价 格:¥电议型 号:T13583产 地:美洲
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T14114AcivicinAcivicin,AT-125,U-42126
Acivicin (AT-125), a natural product produced by Streptomyces sviceus, is a γ?glutamyl transpeptidase (GGT) inhibitor. Acivicin can across the blood-brain barrier and has anti-cancer, anti-parasitic properties[1][2].
价 格:¥电议型 号:T14114产 地:美洲
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T15375GDC-0077GDC-0077,RG6114,
GDC-0077 is an orally available and selective inhibitor of PI3Kα (IC50=0.038 nM). GDC-0077 is more selective for mutant versus wild-type PI3Kα. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylati
价 格:¥电议型 号:T15375产 地:美洲
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T1559Betamethasone dipropionateBetamethasone dipropionate,Betamethasone 17,21-dipropionate,SCH 11460
Betamethasone Dipropionate is the 17,21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors an
价 格:¥电议型 号:T1559产 地:美洲
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T16114PavinetantPavinetant,MLE-4901,AZD2624
Pavinetant is an antagonist of the neurokinin-3 receptor (NK3R).
价 格:¥电议型 号:T16114产 地:美洲
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T16752RimacalibRimacalib,SMP 114,
Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).
价 格:¥电议型 号:T16752产 地:美洲
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T16831(S)-SP5114(S)-SP5114,(S)-SNAP5114,
(S)-SNAP5114 is a selective GABA transport inhibitor (IC50: 5 μM and 21 μM for hGAT-3 and rGAT-2, respectively). (S)-SNAP5114 is an anticonvulsant drug.
价 格:¥电议型 号:T16831产 地:美洲
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T1756Ilaprazole sodiumIlaprazole sodium,IY-81149 sodium,
Ilaprazole, a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an act
价 格:¥电议型 号:T1756产 地:美洲
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T1849MomelotinibMomelotinib,CYT387,LM-1149
Momelotinib is an orally bioavailable small-molecule inhibitor of Janus kinases 1 and 2 (JAK1/2) with IC50 of 11 nM/18 nM. JAK1/2 inhibitor CYT387 competes with JAK1/2 for ATP binding, which may result in inhibition of JAK1/2 activation, inhibition of the
价 格:¥电议型 号:T1849产 地:美洲
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T18975DIDS sodium saltDIDS sodium salt,MDL101114ZA,
DIDS sodium salt is a dual inhibitor of ABCA1 and VDAC1.
价 格:¥电议型 号:T18975产 地:美洲
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T19018K114K114
K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).
价 格:¥电议型 号:T19018产 地:美洲
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T19114(2S,4S)-Sacubitril(2S,4S)-Sacubitril
(2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.
价 格:¥电议型 号:T19114产 地:美洲
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T2114NVP-BEP800NVP-BEP800,VER-82576,
NVP-BEP800, a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.
价 格:¥电议型 号:T2114产 地:美洲