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T81543PARP1-IN-17;化合物 PARP1-IN-17PARP1-IN-17
PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity for PARP-2 (IC50=32.58 nM ) and induces apoptosis. It exhibits robust anti-proliferative activity [1].
价 格:¥电议型 号:T81543产 地:中国大陆
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T81542PARP7-IN-15;化合物 PARP7-IN-15PARP7-IN-15
PARP7-IN-15 (Compound 18) is a potent PARP7 inhibitor exhibiting an IC50 of 0.56 nM and demonstrates antitumor activity [1].
价 格:¥电议型 号:T81542产 地:中国大陆
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T81541PARP7-IN-16;化合物 PARP7-IN-16PARP7-IN-16
PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively. It has potential applications in breast and prostate cancer research [1].
价 格:¥电议型 号:T81541产 地:中国大陆
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T81540Parthenosin;化合物 ParthenosinQuercetin 3-O-β-D-glucuronide butyl ester;Quercetin 3-O-β-D-glucuronide b
Parthenosin (Quercetin 3-O-β-D-glucuronide butyl ester), a flavonoid derived from the aerial parts of Calligoum polygonoides, exhibits cytotoxic properties with IC50 values of 60.46 μg/mL for HepG2 and 61.4 μg/mL for MCF-7 cell lines [1].
价 格:¥电议型 号:T81540产 地:中国大陆
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T8154Fructo-oligosaccharide DP9/GF8;蔗果九糖Fructo-oligosaccharide DP9 / GF8;Fructo-oligosaccharide DP9 / GF8
Fructo-oligosaccharide DP9/GF8 (Fructo-oligosaccharide DP9 / GF8) belongs to fructooligosaccharides (FOS) with the degree of polymerization (DP=9).
价 格:¥电议型 号:T8154产 地:中国大陆
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T81154SIRT1 activator 1;化合物 SIRT1 activator 1SIRT1 activator 1
SIRT1 Activator 1 (Compound 3), a marine-derived xyloallenoide A derivative from the Xylaria sp. mangrove fungus, exhibits angiogenic effects in zebrafish and protects human endothelial progenitor cells (hEPCs) from AngII-induced senescence. It achieves this by elevating SIRT1 expression and modulating the AMPK/Akt signaling pathway [1].
价 格:¥电议型 号:T81154产 地:中国大陆
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T81101ST8154AA1;化合物 ST8154AA1ST8154AA1
ST8154AA1, an antibody-drug conjugate (ADC) component coupled with an HDAC inhibitor via a linker, exhibits antitumor activity [1].
价 格:¥电议型 号:T81101产 地:中国大陆
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T80154TAT-CIRP;化合物 TAT-CIRPTAT-CIRP
TAT-CIRP, a trans-activating (Tat) cold-inducible RNA-binding protein-derived peptide, functions as an inhibitor of myeloid differentiation protein 2 (MD2). It has demonstrated significant neuroprotective effects against ischemic and hemorrhagic stroke in mouse models [1].
价 格:¥电议型 号:T80154产 地:中国大陆
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T80099Ovalbumin (154-159);化合物 Ovalbumin (154-159)Ovalbumin (154-159)
Ovalbumin (154-159), a peptide fragment derived from ovalbumin, acts as a potent inhibitor of the angiotensin-converting enzyme (ACE) and is utilized in hypertension research [1] [2].
价 格:¥电议型 号:T80099产 地:中国大陆
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T79409Antibacterial agent 154;化合物 Antibacterial agent 154Antibacterial agent 154
Antibacterial Agent 154 (Compound 7), a Fluoroquinolone derivative, exhibits broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria when administered orally. It has been shown to be effective in vivo using a mouse model of staphylococcal sepsis [1].
价 格:¥电议型 号:T79409产 地:中国大陆
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T79388Anticancer agent 154;化合物 Anticancer agent 154Anticancer agent 154
Anticancer agent 154 (Compound 8h) enhances reactive oxygen species production, causing mitochondrial damage, and promotes cell apoptosis and DNA damage. It triggers ferroptosis by depleting GSH, diminishing GPX4 expression, and escalating lipid peroxidation. Furthermore, it effectively suppresses the proliferation of various cancer cells (HT29, H1975, A549, and MCF-7) with IC50 values ranging from 1.0 to 1.9 μM [1].
价 格:¥电议型 号:T79388产 地:中国大陆
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T79154Casein kinase 1δ-IN-5;化合物 Casein kinase 1δ-IN-5Casein kinase 1δ-IN-5
Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in vitro, with potential applications in neurodegenerative disease research.
价 格:¥电议型 号:T79154产 地:中国大陆
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T78327Domvanalimab;化合物 DomvanalimabAB154;AB154
Domvanalimab (AB154), a humanized monoclonal antibody targeting TIGIT, inhibits the TIGIT-CD155 interaction and is utilized in cancer research [1].
价 格:¥电议型 号:T78327产 地:中国大陆
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T78154CS640;化合物 CS640CS640
CS640 is a selective calmodulin-dependent kinase inhibitor, targeting multiple isoforms, namely CaMK1D, CaMK1B, CaMK1A, CaMK1G, PIP5K1C, MEK5, RIPK4, and MLK3, with respective IC50 values of 0.08, 0.03, 0.001, 0.001, 11.2, 0.025, 5.69, and 2.75 μM. Additionally, CS640 exhibits inhibitory properties toward CYP450 enzymes 2C9 and 2C19 with IC50 values of 6 and 10 μM, correspondingly [1].
价 格:¥电议型 号:T78154产 地:中国大陆
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T77154Etrolizumab;化合物 EtrolizumabEtrolizumab
Etrolizumab (rhuMAb Beta7), a gut-selective anti-β7 integrin monoclonal antibody, targets the β7 subunit of α4β7 and αEβ7 integrins specifically, demonstrating affinity with K i values of 18 nM for Human α4β7 and 1800 pM for Human αEβ7-293. It is utilized in the research of inflammatory bowel disease (IBD) [1] [2].
价 格:¥电议型 号:T77154产 地:中国大陆
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T76154Triosephosphate isomerase;化合物 Triosephosphate isomeraseTriosephosphate isomerase
Triosephosphate isomerase (TPI), a glycolytic enzyme, efficiently catalyzes the interconversion between dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The catalytic site of TPI is located at the dimer interface [1].
价 格:¥电议型 号:T76154产 地:中国大陆
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T75154ATU027;化合物 ATU027ATU027
ATU027, a small interfering RNA (siRNA), silences protein kinase N3 (PKN3) expression in the vascular endothelium. It has been demonstrated to thwart local tumor invasion, as well as lymph node and pulmonary metastasis, in mouse cancer models.
价 格:¥电议型 号:T75154产 地:中国大陆
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T74154ABP 25;化合物 ABP 25ABP 25
ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.
价 格:¥电议型 号:T74154产 地:中国大陆
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T74072R-BC154 acetate;化合物 R-BC154 acetateR-BC154 acetate
R-BC154 acetate, a selective fluorescent antagonist of α9β1 integrin, serves as a high-affinity, activation-dependent probe for investigating α9β1 and α4β1 integrin binding activity. This compound is particularly useful for detailed studies on integrin interactions [1].
价 格:¥电议型 号:T74072产 地:中国大陆
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T73339Anrikefon;化合物 AnrikefonHSK21542;HSK21542
Anrikefon (HSK21542) is a kappa opioid receptor agonist with analgesic effect [1] .
价 格:¥电议型 号:T73339产 地:中国大陆