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T61850Adenosine receptor inhibitor 1;化合物 Adenosine receptor inhibitor 1Adenosine receptor inhibitor 1
Adenosine receptor inhibitor 1 is a highly potent and selective antagonist of adenosine receptor (AR). It exhibits exceptional affinity for A1 AR, A2A AR, A2B AR, and A3 AR, with respective Ki values of >1000, 68.5, >1000, >1000 nM. This compound demonstrates notable antinociceptive, anti-inflammatory, and peripheral analgesic properties. Therefore, Adenosine receptor inhibitor 1 holds great promise for investigating cancer and neurodegenerative diseases [1].
价 格:¥电议型 号:T61850产 地:中国大陆
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T6185Gambogic Acid;藤黄酸Beta-Guttiferrin|||Guttatic Acid|||Guttic Acid;藤黄酸|||Beta-Guttiferrin|||藤黄酸 A|||Gut
Gambogic Acid (Guttic Acid) ( EC50=0.78-1.64 uM) activates caspases. Gambogic Acid competitively suppresses Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1. The IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively.
价 格:¥电议型 号:T6185产 地:中国大陆
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T61112SLF1081851;化合物SLF1081851SLF1081851
SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM.
价 格:¥电议型 号:T61112产 地:中国大陆
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T60537ARUK3001185;化合物 ARUK3001185ARUK3001185
ARUK3001185 (Compound 8l) is a potent, selective, orally active, and brain-penetrant Notum inhibitor(IC50 = 6.7 nM) that is suitable for oral dosing in rodent models of disease [1].
价 格:¥电议型 号:T60537产 地:中国大陆
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T60185FGFR2-IN-3;化合物FGFR2-IN-3FGFR2-IN-3
FGFR2-IN-3 is an orally active selective FGFR2 inhibitor[1].
价 格:¥电议型 号:T60185产 地:中国大陆
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T5211NSC 185058;化合物NSC 185058NSC185058;NSC185058
NSC 185058 is an inhibitor of ATG4B, a major cysteine protease. It also can attenuate the autophagic activity.
价 格:¥电议型 号:T5211产 地:中国大陆
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T5185PZ-2891;化合物PZ-2891PZ-2891
PZ-2891 is an orally bioavailable, brain penetrant pantothenate kinase (PANK) modulator(hPANK3,IC50:1.3 nM).
价 格:¥电议型 号:T5185产 地:中国大陆
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T4185lavendustin C;N-(2,5-二羟基苄基)-5-氨基水杨酸HDBA|||NSC 666251;HDBA|||NSC 666251|||N-(2,5-二羟基苄基)-5-氨基水杨酸
lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.
价 格:¥电议型 号:T4185产 地:中国大陆
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T41201cis-VZ 185;cis-VZ 185cis-VZ 185
cis-VZ 185 is a negative control for VZ 185.
价 格:¥电议型 号:T41201产 地:中国大陆
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T40185BTK inhibitor 19;BTK inhibitor 19BTK inhibitor 19
BTK inhibitor 19 is a highly selective, covalent BTK inhibitor ( IC 50 = 2.7 nM).
价 格:¥电议型 号:T40185产 地:中国大陆
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T3S1858Lutein;叶黄素Vegetable Lutein|||Xanthophyll|||Bo-Xan|||Xantofyl;Vegetable Lutein|||叶黄素|||Xanthophyll|||
1. Lutein (Xantofyl) has antitumour action. 2. Lutein has antimutagenic action. 3. Lutein has a wide range of antimicrobial action. 4. Lutein is potentially useful for treating macular degeneration.
价 格:¥电议型 号:T3S1858产 地:中国大陆
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T3S1852Cephaeline hydrochloride;吐根酚碱盐酸盐Cephaeline hydrochloride
Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.
价 格:¥电议型 号:T3S1852产 地:中国大陆
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T3S1850Bayogenin;贝萼皂苷元Bayogenin
Bayogenin is an alfalfa saponin, Bayogenin shows moderate potency of glycogen phosphorylase inhibition.
价 格:¥电议型 号:T3S1850产 地:中国大陆
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T39702RO7185876;化合物 RO7185876RO7185876;RO7185876
RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer´s disease.
价 格:¥电议型 号:T39702产 地:中国大陆
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T39229YNT-185;化合物YNT-185YNT-185
YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R, respectively. Furthermore, YNT-185 effectively alleviates symptoms of narcolepsy-cataplexy in mouse models.
价 格:¥电议型 号:T39229产 地:中国大陆
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T39185pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;pp60 (v-SRC) Autophosphorylation Site, Phospho
pp60 (v-SRC) Autophosphorylation Site, Phosphorylated is a phosphorylated peptide derived from an EGFR substrate. It serves as a valuable tool for quantifying phosphorylated substrates in screening EGFR Kinase inhibitors.
价 格:¥电议型 号:T39185产 地:中国大陆
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T37185D-(-)-3-Phosphoglyceric acid disodium;D-3-磷酸甘油酸二钠盐3-Phospho-D-glyceric acid disodium;3-Phospho-D-gly
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) is an intermediate in several biological pathways, most notably glycolysis/gluconeogenesis and the biosynthesis of serine, glycine, and threonine, which competitively inhibits yeast enolase. It also has numerous roles as an intermediate in biosynthetic pathways in plants, eukaryotes, and prokaryotes.
价 格:¥电议型 号:T37185产 地:中国大陆
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T37112YNT-185 dihydrochloride;YNT 185YNT-185 dihydrochloride
Potent and selective orexin OX2 receptor agonist (EC50 = 28 nM at human OX2 expressed in CHO cells). Displays approximately 100-fold selectivity for OX2 over OX1 (EC50 = 2.75 μM at human OX1 expressed in CHO cells). Depolarizes OX2-expressing histaminergic neurons in mouse brain slices. Increases wake time in wild type mice. Suppresses cataplexy-like symptoms in OX knockout mice.
价 格:¥电议型 号:T37112产 地:中国大陆
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T36405Pro-Adrenomedullin (153-185), human;Pro-Adrenomedullin (153-185), humanPro-Adrenomedullin (153-185),
Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaechromyctoma in 19931. AM was initially identified as a vasodilator, some have cited this as the most potent endogenous vasodilatory peptide found in the body2. Differences in opinion regarding the ability of AM to relax vascular tone arises from the differences in the model system
价 格:¥电议型 号:T36405产 地:中国大陆
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T36185Globotriaosylceramides (hydroxy) (porcine);Globotriaosylceramides (hydroxy) (porcine)Globotriaosylce
Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G
价 格:¥电议型 号:T36185产 地:中国大陆