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产品数:86101
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T741954′-Demethylnobiletin;化合物 4′-Demethylnobiletin4′-Demethylnobiletin
4′-Demethylnobiletin, a bioactive metabolite, activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and reverses memory impairment linked to NMDA receptor antagonism through ERK signaling stimulation [1].
价 格:¥电议型 号:T74195产 地:中国大陆
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T73195EAPB 02303;化合物 EAPB 02303EAPB 02303
EAPB 02303 is a microtubule-disrupting agent and inhibitor that induces mitosis arrest and spindle assembly impairment, leading to apoptosis (programed cell death) and demonstrating antitumor activity. Furthermore, it exhibits potent synergy with Paclitaxel at lower concentrations [1].
价 格:¥电议型 号:T73195产 地:中国大陆
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T72195KCa1.1 channel activator-2;化合物 KCa1.1 channel activator-2KCa1.1 channel activator-2
KCa1.1 channel activator-2, a hybrid derivative of Quercetin, selectively stimulates the vascular KCa1.1 channels. This compound demonstrates significant myorelaxant activity.
价 格:¥电议型 号:T72195产 地:中国大陆
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T71958BZX2;化合物 BZX2BZX2
BZX2 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.
价 格:¥电议型 号:T71958产 地:中国大陆
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T71957Cupferron;化合物 CupferronCupferron
Cupferron is a superoxide dismutase inhibitor.
价 格:¥电议型 号:T71957产 地:中国大陆
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T71956Pimprinine;化合物 PimprininePimprinine
Pimprinine is an alkaloid. It is a potent inhibitor of MAO (monoamine oxidase). More recently, pimprinine showed promising anticonvulsant activity in electric seizure threshold.
价 格:¥电议型 号:T71956产 地:中国大陆
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T71955C3001a;化合物 C3001aC3001a
C3001a is a selective activator for TREK, against other two-pore domain K+(K2P) channels. C3001a binds to the cryptic binding site formed by P1 and TM4 in TREK-1. C3001a targets TREK channels in the peripheral nervous system to reduce the excitability of nociceptive neurons. In neuropathic pain, C3001a alleviated spontaneous pain and cold hyperalgesia. In a mouse model of acute pancreatitis, C3001a alleviated mechanical allodynia and inflammation. C3001a represents a lead compound which could a
价 格:¥电议型 号:T71955产 地:中国大陆
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T71954MMG-0358;化合物 MMG-0358MMG-0358
MMG-0358 is a novel potent IDO1 inhibitor, showing low cytotoxicity and higher selectivity for IDO1 over TDO enzyme.
价 格:¥电议型 号:T71954产 地:中国大陆
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T71953Thiol-PEG2-acid;化合物 Thiol-PEG2-acidThiol-PEG2-acid
Thiol-PEG2-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
价 格:¥电议型 号:T71953产 地:中国大陆
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T71952DDD01035881;化合物 DDD01035881DDD01035881
DDD01035881 is a novel transmission blocker of antimalarials, targeting male gametes.
价 格:¥电议型 号:T71952产 地:中国大陆
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T71951AS-1940477 hydrobromide;化合物 AS-1940477 hydrobromideAS-1940477 hydrobromide
AS-1940477 hydrobromide is a p38 mitogen-activated protein kinase (MAPK) inhibitor.
价 格:¥电议型 号:T71951产 地:中国大陆
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T71950PSB-12054;化合物 PSB-12054PSB-12054
PSB-12054 is a potent P2X4 receptor inhibitor. PSB-12054 has IC(50) of 0.189 μM and good selectivity versus the other human P2X receptor subtypes.
价 格:¥电议型 号:T71950产 地:中国大陆
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T7195GSK369796 Dihydrochloride;化合物GSK369796 DihydrochlorideN-tert-butylisoquine;N-tert-butylisoquine
GSK369796 Dihydrochloride (N-tert-butylisoquine),is an anti-malaria drug candidate. is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization(IC50 of 7.5 μM)
价 格:¥电议型 号:T7195产 地:中国大陆
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T71685NEU-1953;化合物 NEU-1953NEU-1953
NEU-1953 is a potential candidate for sleeping sickness.
价 格:¥电议型 号:T71685产 地:中国大陆
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T71363ACT-281959;化合物 ACT-281959ACT-281959
ACT-281959, a prodrug of ACT-246475, is a novel potent and selective P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. ACT-281959 showed antithrombotic efficacy after oral administration in the rat ferric chloride model. ACT-281959 entered clinical studies in healthy volunteers.
价 格:¥电议型 号:T71363产 地:中国大陆
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T71195mPTP-IN-22;化合物 mPTP-IN-22mPTP-IN-22
mPTP-IN-22 is a novel mitochondrial permeability transition pore (mptp) inhibitor
价 格:¥电议型 号:T71195产 地:中国大陆
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T70734U46,195;化合物 U46,195U46,195
U46,195 stimulates the production of tissue-type plasminogen activator, and is a PAF antagonist.
价 格:¥电议型 号:T70734产 地:中国大陆
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T70680BMS-961955;化合物 BMS-961955BMS-961955
BMS-961955 is an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
价 格:¥电议型 号:T70680产 地:中国大陆
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T70402LAS195319;化合物 LAS195319LAS195319
LAS195319 is a potent and selective inhaled PI3Kδ Inhibitor (IC50 = 0.5 nM) for the Treatment of Respiratory Diseases.
价 格:¥电议型 号:T70402产 地:中国大陆